Entrez gene ID | | 259197 |
Official gene symbol | | NCR3 |
Full name | | natural cytotoxicity triggering receptor 3 |
Aliases | | ,1C7,CD337,LY117,MALS,NKp30, |
Gene summary | | The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 31560762 - 31556660 Map Viewer |
Gene orientation | | minus |
Gene size | | 4103 bp |
Gene sequence |
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OMIM ID | | 611550 |