Entrez gene ID | | 25920 |
Official gene symbol | | NELFB |
Full name | | cofactor of BRCA1 |
Aliases | | ,COBRA1,NELF-B, |
Gene summary | | NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM] |
Location | | Chromosome: 9 Locus: 9q34 |
Gene position | | 140149759 - 140168000 Map Viewer |
Gene orientation | | plus |
Gene size | | 18242 bp |
Gene sequence |
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OMIM ID | | 611180 |
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