Entrez gene ID | | 259266 |
Official gene symbol | | ASPM |
Full name | | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
Aliases | | ,ASP,Calmbp1,DKFZp686N06184,FLJ10517,FLJ10549,FLJ43117,MCPH5, |
Gene summary | | This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. |
Location | | Chromosome: 1 Locus: 1q31 |
Gene position | | 197115824 - 197053257 Map Viewer |
Gene orientation | | minus |
Gene size | | 62568 bp |
Gene sequence |
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OMIM ID | | 605481 |
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