Entrez gene ID | | 26035 |
Official gene symbol | | GLCE |
Full name | | glucuronic acid epimerase |
Aliases | | ,HSEPI,KIAA0836, |
Gene summary | | Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM] |
Location | | Chromosome: 15 Locus: 15q23 |
Gene position | | 69452973 - 69564544 Map Viewer |
Gene orientation | | plus |
Gene size | | 111572 bp |
Gene sequence |
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OMIM ID | | 612134 |
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