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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GLCE (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26035
Official gene symbolGLCE
Full nameglucuronic acid epimerase
Aliases,HSEPI,KIAA0836,
Gene summaryHeparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM]
LocationChromosome: 15   Locus: 15q23
Gene position69452973 - 69564544  Map Viewer
Gene orientationplus
Gene size111572 bp
Gene sequence
OMIM ID612134