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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for APPL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26060
Official gene symbolAPPL1
Full nameadaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Aliases,APPL,DIP13alpha,
Gene summaryThe protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21.1-p14.3
Gene position57261765 - 57307499  Map Viewer
Gene orientationplus
Gene size45735 bp
Gene sequence
OMIM ID604299