Entrez gene ID | | 26088 |
Official gene symbol | | GGA1 |
Full name | | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
Aliases | | ,-, |
Gene summary | | This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.31 |
Gene position | | 38004481 - 38029571 Map Viewer |
Gene orientation | | plus |
Gene size | | 25091 bp |
Gene sequence |
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