Entrez gene ID | | 26091 |
Official gene symbol | | HERC4 |
Full name | | hect domain and RLD 4 |
Aliases | | ,DKFZp564G092,KIAA1593, |
Gene summary | | HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM] |
Location | | Chromosome: 10 Locus: 10q21.3 |
Gene position | | 69835103 - 69681656 Map Viewer |
Gene orientation | | minus |
Gene size | | 153448 bp |
Gene sequence |
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OMIM ID | | 609248 |
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