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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HERC4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26091
Official gene symbolHERC4
Full namehect domain and RLD 4
Aliases,DKFZp564G092,KIAA1593,
Gene summaryHERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM]
LocationChromosome: 10   Locus: 10q21.3
Gene position69835103 - 69681656  Map Viewer
Gene orientationminus
Gene size153448 bp
Gene sequence
OMIM ID609248