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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SENP3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26168
Official gene symbolSENP3
Full nameSUMO1/sentrin/SMT3 specific peptidase 3
Aliases,DKFZp586K0919,DKFZp762A152,SMT3IP1,SSP3,
Gene summaryThe reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM]
LocationChromosome: 17   Locus: 17p13
Gene position7465319 - 7475287  Map Viewer
Gene orientationplus
Gene size9969 bp
Gene sequence
OMIM ID612844