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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SPAG8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26206
Official gene symbolSPAG8
Full namesperm associated antigen 8
Aliases,BS-84,HSD-1,MGC26201,SMP1,SPAG3,hSMP-1,
Gene summaryThe correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq]
LocationChromosome: 9   Locus: 9p13.3
Gene position35812259 - 35807782  Map Viewer
Gene orientationminus
Gene size4478 bp
Gene sequence
OMIM ID605731