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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26232
Official gene symbolFBXO2
Full nameF-box protein 2
Aliases,FBG1,FBX2,Fbs1,NFB42,OCP1,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.22
Gene position11714739 - 11708448  Map Viewer
Gene orientationminus
Gene size6292 bp
Gene sequence
OMIM ID607112