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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXL6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 26233 Official gene symbol FBXL6 Full name F-box and leucine-rich repeat protein 6 Aliases ,FBL6,FBL6A,PP14630, Gene summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq] Location Chromosome: 8   Locus: 8q24.3 Gene position 145582132 - 145579091  Map Viewer Gene orientation minus Gene size 3042 bp Gene sequence >FBXL6:complement(124690..127731):Length=3042 GCTTCCCCGAGCGCCGTCGGTGGTCATGGCTGCCCCAGCCTCCCGGCAGGTCCGACGCAG AGCCCGGGCAGCGCCGCGGCCCCGCTCGGCCGAGGACTGGTGGTGGGACCGGCTGGCGCC GAGGGGCTCGGGGTACCACCTGCTGCAGTCCGACAGCATGCTGCTGGTGCTGTCCGAACC CGGCCCCGCCCGGCCCCGCGCACAGCGGCGCGCTTCCCGCCGCACTCCCCGGCAGCCGCC CCGGGGCCCCAGCGCCGCGGCCAAGCCCAAGGCCGGGCTCAGGTCCGAGGCGGCGGCCGC GCCCGCACCCGCACCGGCACCCACGCCCACGCCCGAGGAAGGGCCCGACGCGGGCTGGGG AGACCGCATTCCCTTGGAAATCCTGGTGCAGATTTTCGGGTTGTTGGTGGCGGCGGACGG CCCCATGCCCTTCCTGGGCAGGTAACGCTGGTGCCGGGCCCGCCGCCGAGCGTAGCGGCT TGGGCCAGACGTGGTCCGAGCGGTGGCCCGGGCGGGGGCGGAGGGCGAAAGCATCGGAGC GCGCACCGCTCAGTCCGAGAGCGCAGCCCCTTAGGCGCCCAGTTGGAGTCCCAGGAGCCC GGCTTTGAGCCGGGGTGTCTACTGCGCTGCGAGAGGGGGGCATCGCCTACGGAGGGGCCG GCACCCTCAGCACGCTGTCCTCCCAGGGCTGCGCGCGTGTGCCGCCGCTGGCAGGAGGCC GCTTCCCAACCCGCGCTCTGGCACACCGTGACCCTGTCGTCCCCGCTGGTCGGCCGGCCT GCCAAGGGCGGGGTCAAGGCGGAGAAGAAGCTCCTTGCTTCCCTGGAGTGGCTTATGCCC AATCGGTGAGGGGTTCCCTCTCTTCCTTACCCCTGGCTCCAGGCTCCTTCCGTCTCCCTG CACCAAGGTGTTGGGTGGGAAGGACTCGTGTGGGAACATTAGTGCAGCTCTGCCTCCGCT GTCGGCCCAGGTTTTCACAGCTCCAGAGGCTGACCCTCATCCACTGGAAGTCTCAGGTAC ACCCCGTGTTGAAGGTGAGAGCTCCAGGCTGTCCTGCACATCAGCTGTGACACTCTGGGA CTGTTCAGTACTCTAGGAAGTGGGTCAGGCACCTTGGGGGCCCAACGCTGCTCCGTGGGG ATGTCTGCCTGCCTGCCTGGTTCTCTTTTCCTGCTGTTTCCTCCAGCAGGGAGGTATCAG AGGCGGGGACACCCAAGTAGGCCTGGCATGGGCAGAAAGGAGGTCACAGCTAAGGCGGTA GAGTGGGGTTGGCACCAGCCACTTGTCTGTTTCCCTTGTGGATCTTAGCCTGTCGTCTCC CAACCCCAGCTGCCCCTCTGTCTCCCCGCAGCTGGTAGGTGAGTGCTGTCCTCGGCTCAC TTTCCTCAAGCTCTCCGGCTGCCACGGTGTGACTGCTGACGCTCTGGTCATGCTAGCCAA AGCCTGCTGCCAGCTCCATAGCCTGGACCTACAGCACTCCATGGTGAGCCCTGTGTCCCA AGGGGCCCTGAAAAAACCCAGGCCGGGGTGACGGGTGCTCTTGTATTGGGGCCCCAGGTG GAGTCCACAGCTGTGGTGAGCTTCTTGGAGGAGGCAGGGTCCCGAATGCGCAAGTTGTGG CTGACCTACAGCTCCCAGACGACAGCCATCCTGGGCGCACTGCTGGTAAGTTGGCATTGG TGGGAGCAGAGGCAGATGCTGAGCTGGGGACTGCCAGGCCACTGACCCTGTGACCTACCC CCTCCCCCCATCTCTGCAGGGCAGCTGCTGCCCCCAGCTCCAGGTCCTGGAGGTGAGCAC CGGCATCAACCGTAATAGCATTCCCCTTCAGCTGCCTGTCGAGGCTCTGCAGAAAGGCTG CCCTCAGCTCCAGGTACCTGGCGCCCTGCCTCTCCCACCTGTCACACCCTCCCCCATCTA CAGCCTGGACCTTGCCCCCAGGTGCTGCGGCTGTTGAACCTGATGTGGCTGCCCAAGCCT CCGGGACGAGGGGTGGCTCCCGGACCAGGCTTCCCTAGCCTAGAGGAGCTCTGCCTGGCG AGCTCAACCTGCAACTTTGTGAGCAACGAGGTCCTGGGCCGCCTACTCCACGGCTCTCCC AACCTGCGCTTACTGGATCTTCGTGGCTGTGCGCGCATCACGCCGGCTGGCCTTCAGGAT CTGCCATGTCGGGGTCAGCAGTCCTGGGTGGTGGCCGGGCGGGTGAGGTGTGGGGGCCCT TGTCACCTTGTAGCTTATGCTCACTCCTTTCACTGCAGAGCTGGAGCAGCTTCATCTGGG CCTGTATGGCACGTCAGACCGGCTGACTCTAGCCAAGGAGGGCAGCCCCTTTTTGACCCA GAAGTGGTGCCATACACTGCGAGAACTGGACTTGAGTGGCCAGGGGTTCAGTGAGAAGGA CCTGGAGCAGGCCCTGGCTGCCTTCTTAAGCACCCCTGGGGGCTCACACCCAGCCCTGTG CTCTCTTAACCTCAGGGGCACCCGGGTCACACCAAGCACTGTCAGGTCAGCATCCCCTAC CCCAGTCCCTGGAGCCAGTGTGGCTGTCACTGTGTCTGCCTGGGGCCTGGAAGTTGTGTC CTGCCTGGCCTGAGACCTCCAGGGGTCAGAGGGGCATGCATACTGTCCAAGCCCCTGCGT GGGGTGGGCCTGAGGACACCAGGGGAACTGGGCTTGGCCTTGGTGGCTATGGGTGGCAGA GCCAGGTGTCGAACACCAGCAGGCACAGCTCCCTAGCCTGGCCCAGCCCTTCTGAGGCAA CAGCTCAACTTCCTGTGGTCTGCCCTCCCCACAGCTCTGTGATCAGCGGCTGCCCGGGCC TGCTCTACCTCAACCTGGAGTCCTGCCGCTGCCTTCCCCGGGGTCTGAAGCGGGCCTACC GGGGCCTGGAGGAAGTCCAGTGGTGTCTGGAGCAGCTGCTCACCAGCCCCTCACCCAGCT AGGCAGCCACAGACCTGGGACACCTCAGCCAGCTTGCCCACCCTCCACCTTTGCCCAATT TCAGATATTTGAGCATTTTGTTAAAATAAAACATTTTTAGGA OMIM ID 609076