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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXL5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26234
Official gene symbolFBXL5
Full nameF-box and leucine-rich repeat protein 5
Aliases,FBL4,FBL5,FLR1,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq]
LocationChromosome: 4   Locus: 4p15.32
Gene position15657035 - 15606007  Map Viewer
Gene orientationminus
Gene size51029 bp
Gene sequence
OMIM ID605655