Entrez gene ID | | 26234 |
Official gene symbol | | FBXL5 |
Full name | | F-box and leucine-rich repeat protein 5 |
Aliases | | ,FBL4,FBL5,FLR1, |
Gene summary | | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p15.32 |
Gene position | | 15657035 - 15606007 Map Viewer |
Gene orientation | | minus |
Gene size | | 51029 bp |
Gene sequence |
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OMIM ID | | 605655 |
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