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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26270
Official gene symbolFBXO6
Full nameF-box protein 6
Aliases,FBG2,FBS2,FBX6,Fbx6b,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.22
Gene position11724150 - 11734411  Map Viewer
Gene orientationplus
Gene size10262 bp
Gene sequence
OMIM ID605647