Entrez gene ID | | 26270 |
Official gene symbol | | FBXO6 |
Full name | | F-box protein 6 |
Aliases | | ,FBG2,FBS2,FBX6,Fbx6b, |
Gene summary | | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p36.22 |
Gene position | | 11724150 - 11734411 Map Viewer |
Gene orientation | | plus |
Gene size | | 10262 bp |
Gene sequence |
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OMIM ID | | 605647 |
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