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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARFGAP3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26286
Official gene symbolARFGAP3
Full nameADP-ribosylation factor GTPase activating protein 3
Aliases,ARFGAP1,FLJ45618,
Gene summaryThe protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q13.2-q13.3
Gene position43253408 - 43192532  Map Viewer
Gene orientationminus
Gene size60877 bp
Gene sequence
OMIM ID612439