Entrez gene ID | | 26462 |
Official gene symbol | | Txnrd2 |
Full name | | thioredoxin reductase 2 |
Aliases | | AA118373,ESTM573010,TGR,Tr3,Trxr2,Trxrd2 |
Gene summary | | This gene product belongs to the family of pyridine nucleotide-disulfide oxidoreductases. It is a mitochondrial enzyme that catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. This protein contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16 A3|16 11.2 cM |
Gene position | | 18426510 - 18479166 Map Viewer |
Gene orientation | | plus |
Gene size | | 52657 bp |
Gene sequence |
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