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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPN18 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 26469 Official gene symbol PTPN18 Full name protein tyrosine phosphatase, non-receptor type 18 (brain-derived) Aliases ,BDP1,PTP-HSCF, Gene summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 2   Locus: 2q21.1 Gene position 131113580 - 131132982  Map Viewer Gene orientation plus Gene size 19403 bp Gene sequence >PTPN18:20862243..20881645:Length=19403 GAGGCAAGGGCGGGGACTCAGTCACCGGCCTCCGCCTCCCGCGGCGTCCACACTCGCCGC GCGCGCGGCGGCCGGGCTGGACCTTGCTGGCCCGCGGCGCCATGAGCCGCAGCCTGGACT CGGCGCGGAGCTTCCTGGAGCGGCTGGAAGCGCGGGGCGGCCGGGAGGGGGCAGTCCTCG CCGGCGAGTTCAGCGTGAGTGGCACACGGGGTCCGCGAGCGGCGCGCCCCGGCCCTGGCC CTGCGTACGCCTGTCCTCCGCGCACGGCGGGCTCTGCCTTTCTGTCTCGGTGTCCCCGGT GTCTCCCCGCCTCGGGGGGTCTCTCCGTGTTTCTCTCCCCAGCACTTCTCTGTCGCTCTT GCTGTCTCCGTCTTCACTCTCTGCCCCCCGGCCCCGGAGCGCGACGTCCACGGCCAGGCC GGGACGGACCGTGCACACCCTCGTTCCCGGTGTCCTCGTCGCGCTCCCGGAACAACCTGG CTGCGGGCGGGACAGGTGGGGCGGGCGCCGCAGGGGAGGGCGGGCGGCCCTGCTGCGCTG GACAGCCCCGGCCCCGCCGCTTCTGGCGACCTGACTGTCCCCTGTGACCACAGGAAGGAA GGGGCTGCAGCAGGGCGAAGAGGAACACGGAGGCTGTGGCGTGGTGAGGGTGTGAACGCC GGGCTCGAATCCGCGTCCGGGCCCGAATCCGCTTCCCGTCCCGAATCCGCGTCCCGGCCA TCCGCGTGTGGTCCAGGCGGTCTACCTGGCCCCTCTGACCTCGGCTTCTCCCTTGGTGAA ATGGGGACATGAATGACCAAACTGGTCTAAGGATTAAATGATGTGGGTGAAAAGCACTTA GTACATATTGGGCGCACACTTCGTAGGGGCGTTCGTCACTGCCTATAAAGATTCTAAACG TGGGCCAGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGAG GATCGCTTGAGCTCAGGAGTTCGAGACCAGCCTGGGCAACACAGCGAAACCCCGTCTCTA CTAAAAATACAAAAATCAACTGGGCATGGGCGCATGCCTGTAATCCCAGCTACTAGGGAG CAGAGACAGGGGACTCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATGGTTC CACTGCACAGCTGAGATGGTGCCACTGCACTCCAGCCTGGGCCACAGAGTGAGATCCCAT CTCAAACAAAACAAAACCAAACAAAAAATCTAAACGTTACAATACAGGTAGTGCAAGCCC AGCATTAGGAAGGCTCACGCAGAATGCTAGGCACTGTACATTACAGTTGATGACGTGTTT AAAGTGTAATCGCTTATGTACCAGACATAGAAACATACCATACAAACGCATAAACTGATA TATGGTGACATGTATCAAGTTTAGAAATATGACAAATATATAAAAGTATTATAAATGACC GTTTATACAATAAACATTGCATAACTGCATAAAACAATACAACAAATGAATATAACAAAG ATTATAATTTATAAAATGACCAAAGTTATTTGATAAATTCATAAGTAGATATAAAATATG TAACAGATGGCCGGGCACGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCGAGG CGGGCGGATCACGAGGTCAGGAGATCCACACCATCCTGGCTAACACGGTGAAACCCCGTC TCTACTAAACACACAAAAAATTAGCTGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTAC TCGGGTGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGA GATCGCGCCACTGCAGTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCAAAAAAAAAAA AAAAAAAAGTAACAGATAATTATAAACCTAAGTAATTTACACACATGTAGAAACATTGTA TATAAGAAACTAAGAAATGCATAATAAATGTAAAATATATAATTATACAATATAAGAATG TGTGTAACAAATGTAAACATAATACCCATGTGATATATGACATCATGCGACTGGGTGGGT TCTGAACCGTGTACAGTGCGGAGGGCCTCACATGCGGAAGGCTGGGTGGCGAGGGCACCC CTGCTCCCCAAGCCTGCCTCCCGCATGTGCAGGAATCACTGCGCTCTTCTAGGTGTTCCC ACTACACAAGGGCATCATGAGGGCTTAAATGACCCAATGGACACAAGTAAAGCACTTAGA ATAGTGGCTGGCACACAGTGGTGGCATGGGTGTTACTTATTATCATTGAGATTACGAATA CCTGACGATGATGGTAATACACGATTCACTAATTATTATTATAATCTCCCAGTAACACAG TGCCTATAGTATCTTGTACATAATATGTTATCCATTATAATGCCTATGCATTCATTGTAC ATTGTCTTATATGTTTAGCTACATAGCCCATAATATATTTCATTACAGTTATTGCTTACA AGACAATGTCACAGATTGAGTGTGCAGGGGGTGGGTGCCGAGAGGGTCTGAGTTCAACCC TCACCGTGTGACTTCCTGGTTGGGACCTTCCACAAGTCGCTGAACCACGTGGTGCATAAA CTTTCCCGCCTGCACAATGGGGACGTCAATAATAGTACCCACGTCGTAGGAACCTGTGAT GATTACATGCCCTTAGCACAGAGAGTGGCACAGAGAAGGTGCCCTGGGTCACTATTTCGG TATCATTATTATTAGGCAGGCCCAGTGCCATCAGGGTCTGCACTCACCTCCCCAGGCCAC TGGCTTTGTATCCTGCAAGCGTGCCTAGGTGGCCTGGGACTCTGACCTGGCTCCTCTCCT GTCTTCTCCCCTCCCTGACCCACTCATAATGCTCTACCAGGACATCCAGGCCTGCTCGGC CGCCTGGAAGGCTGACGGCGTGTGCTCCACCGTGGCCGGCAGTCGGCCAGAGAACGTGAG GAAGAACCGCTACAAAGACGTGCTGCCTTGTAAGTCGGGGCTTCCGTAGGGAGTCGGTGC AGCCTTGCACGCCCTGCCACGTCCAGGCGTCAGTGTGCACTGGAGTCACCCACTGTGCTC TCCTCCCAGAGCCTCACCCTCTGCACTGCTCAGCAGCCCACAAGGGCACCTTGGTGGGAT CTCTGCATGTGTGTGGTCCCCTGCTGGCTTTCAGCTAGGGGGCTGTCAGAGGCTCCGTCA CCCTATCCTACCCAAACTCCACGTTTCTCACCTTATCTGCTGACAGATGATCAGACGCGA GTAATCCTCTCCCTGCTCCAGGAAGAGGGACACAGCGACTACATTAATGGCAACTTCATC CGGGTGAGGGTTGGGGTCACGGAAGGAGGTGGACTGGGAGTGGCCAGGGGTGGGCCGCAG AATCTCAGTCGTGAATTCGGCCTTCACCAGGGCGTGGATGGAAGCCTGGCCTACATTGCC ACGCAAGGACCCTTGCCTCACACCCTGCTAGACTTCTGGAGACTGGTCTGGGAGTTTGGG GTCAAGGTCAGCACTTGGGGGTGCGGCACAATGGTGGGGTCAACATCTAAGTACCCCCTC GGCAGTTTCCCTGGCCCCCTCACCCAAATCACCTTCCTCTCCCCTGACCCTCCTTGTCTA GGTGATCCTGATGGCCTGTCGAGAGATAGAGAATGGGCGGGTAGGTGCCCTCTGCCCCCA GGTTTCATGTCCTTGTGGGAGGAGGGAGGAGGGATCTTGCTAGCTCCTCCTTGACCCCAG GACCCGAGGGTCCAGCTCTTGGAGTGACCTTATTGTAGCTCTGTGGGAAGCCCCATTGTT CCTCTAAGTTTTTGTTGATATGTTATTCATCCCCCAGTGTTGGCAACCCCTCTCCTGCTG GGCTTCCCAGCCATTTCACACCTTAGACCATAAGGCCCTATTCTGACTGCTTCCCCTGTA GGCTCTGATCTCTCTTTCCACCTCTCTTCCCTTTATTCACTCCACTCTAACAACTCTGGT CTCTGCTGTTCCCATGTTCCAGGGATGGCTCTGCCTCAGGGTCTGTGCCTTGGCTATTCC TTCAGCCTAGGACATCCTTCCCTGTGGCTTGCTCTATCACCTCCTTCAGGTCTTTGCTCA AATGGTAATTCCTCAATGAGACCTTCCGGGGTGGGTCTTCACACCATTTTAAACTCTCAG CACTTCCATTCTCCCTCCCTTGTCCTACTTTTCCTTCTTTCTTCACAGTTCTTATGAACT CCTAACACACTGGATAATCTACAAATGTATTATGTACATTGTTTATGCTTAATCTCCCTG ATTTAGAAGGTAAGATCCACAAGGCCAGGGATTTTTGTTTTGCCTGTTAACATAAATTAG TTACTAAATAAATAAATGCATGTCAATATTGAAGGCTGAAGGCACATAGCTTCATGTGGT TTCTACATTCTTGCCTACTCCATGGATGGGGTAGGGGTTCCCTGGGGTGACTAGCTGATG GTGGAGGCTGTATGATCTGTAGTCTTGTCTCTTTCTCATTCCTGATTTTGGTAATTTGTG TTCTCTCTCTCTCTCTGTCTCATCTCTCTATTTCGCTATCTCTTTTTTCATGCTCCTGCC TGTTTTTTGTAAACAGTGTATTAGAACACAGCCACACTCATTTATTTACATATTGTGTAT GCCTGCTTTTATGCTACAGTGGCAGAGTTGAGTAGTTGCAAGTTGAATAAATTATATGGC CTGTAAATTCTAAAGTATTTATCTGACCCTTTATAAAAATGTCAGCCAATCTTTGGACTA GAAGTTTATCATTTTATTATTTTTTCAAAGAACCTGCTTTGGTTGTATTCATTTGTATTC ATTTTCTCTATTGATTTTTTCATTTTCCACTTTTTTTTTTTTTGAGACAGAGTCTTGCTC TGTTGCCCAGACTGGAGTGCAGTGGTGCAATCTTAGCTCACTGCAACCTCTGCCTCCCAA GTTCAAGCAATTCTCCTGCCCCAGACTCCTGAGTAGCTAGGAATACAGACACATGCCACC ACGCCCAACTAATTCATTTTCTACTTTAATTTCAAGTGTACTTGAAAACAATGTGTATTC TGCTTTGGTTGGCTGGAGTGTCCTGTAAATACCAATTAGGTCAACTGACAGACTTTTTAA AAAGACACTTTTATATCTTTACTGTATATTTTATATCTTTACTGATTTATTTTCTCTAAA TGTATGGATTGCTTAGAGAGGAGTGTTGAAATTACCAACTGTTCAATAAGTATTAATTAG GTCAAGTTTGTCAACAGCACTATTCAAGTCTTATTTCTGACAATTTTTTTTGTCTGCTTG CCCTATTATTTGCTGAAAGAGGAATGTTGAAATCTGCTTTAACTATTCTTTCAGTTTTAC TTTTCATGTTTTAAAACTTTATGATTGAGTACATATACATTTAGGATTATGTCTTCCTAA TGATTGGATCCCTTTCTAATATGTAATGACTCTTTATTTGTTAATATTTTTTTCTGAAGT GTACTTTGATATTAATACAGCCATTTAAATTTCTTTCTTTTCTTTCTCTTTCTTTCTTTC TTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCCTTTCTTTCCTTTCTTTCCT TTCTTTCTTTCTGTTTTTTTGAGATGCAGTTTCCCTCGTCACCCAGGCTGGAGTTCAATG GCGCGATCTTGGCTCACTGCAACCTTTGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAG CCTCTCGAGTAGCTGGGATTGCAGGTGCCTGCCACCACGCCCAGCTAATTTTTGTATTTT TAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGCCCTCAGGTG ATCCACCCGCCTCAGCCTCCCAAAGTCCTGAGATTACAGGCATGAGCCACCGCCCTCGGC CTTAAATTTCTTTAGAGTTTGCATATGTCTTTTCCCATTCTTTTACTTTGTATCTATGTT CATCTTTATTTTTTAGTGTGTTTCTTGTAGGTGGTGTATTGTAGGGACTTTTTTTTTTTA AGACAGAGGGGAATGGAGTGGTGCAATCATAGTTCACTGTAACCTCAAAATCCTGGGCTC AAATGATCATGCTAGCGCAGCCTCCCTGAGGAGTTGGGACTACAGGCATACACCACCGTG CCTGATTAATTGTTTTTTATTTCTTGTAGAGATTAAGTCTCACGTATAATCCAGGCTGGT CTCGAACTCCTGGCCTCAAGCTGTCCTTCCACCTCGGCCTCCCAAAGTGCTAAGATTACA GGCATGAGCCACTGCATCTAGCCAGGACTTACTTTTAAATCTAATCTGACAGTCTCTGCC TTTAATTGGAATATTCAGCCTTTAATGTAATTATCAATAATGTTGGGTTTAAACCTACCA TCTTGCTATTTGTTTTCTATTTGCTCTGTTTGTTCTTTTCTTCTTTTTTTCTCTTTCAGA GTGAGAATTTTTTATTAATCTATTGCATAGTAATTATTCCCTTATTAGCTATACATCTTT ATTTTAAATATTTAGTTGTGGCTTTAGGGTTTACAATATATATCTTTAACTTATAGTCTA TAGTCAAATAATATTCTACATTTCATGTAAAATGTCAGAACTTTACTGTAGTATATTTCG ATTACCCCTTTCCATGCTTTGTGCTATTGTTACTATATATTATAGTTCTATATATAAAAT ATACTCCACAGTACACTGCTATTATAGTTGTTTTAGAATATCTTTTTAAACAGCTTTATT GATATACAATTCAGTCATTTAAAGTGTACAGTTCCATCATTTTTCTATATTCCTGAGCTA TGCAACTATTACCACAGTAAGATTTTTGTTTTTGTTTTTGTTTTTGTTTTTGAGACGGAG CCTCGCTCTGTCCTCCAGGCTGGAGTGCAATGGCGCGATCTCAGCTCGCTGCAACCTCCG CCTCCCGGGTCCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTAGGACTACAGGCGC CTGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTA GCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAGTGCT GGGATTACAGGCATGAGCCACCGTGCCCGGCCTACCACAATAAGTTTTTGAACATTTTCA TCATTCCATAAAAAAATCCAGGCCAGACATGGTGGCTCATGCCTGTAATCCCAGCACTTT GGGAGGCTGAGACTGGTGGATCACGAGGTCAGGAGATCAAGACCATCCTGGCCAACATAG TGAAACCCCGTCTCTACTAAAAATACAAACATTAGCTGGGCATGGTGGCATGTGCCTGTA ATCCCAGCAACTCGGGAGGCTGAGGCAGAAGAATAGCTTGAACCAGGGAGTTGGAGGTTG CAGTGAGCTGAGATTGTGCCACTACACTGCAGCCTGGCCACAGAGCAAGACTGTCTCTCA AAAAAAAAGAAAAAGAAAAGAAATCCTATATCCATTAGCAGTCACTCCCCATTTCCCAGC AACCTCTACAGCCCCAGACAATCCCTAATCTATTTTTGCCTTTATACATTTGCTTACTTT GGACATTTCATATAATTGAATCACATAATATGTAGCCTTTTTTTGCTTAGCATTTTTGTT TTGTTTTGTTTTGTTTGCTGAATACTATTCCATTGAATGGATCTACCACATTTTACTTAT TGGTTGACAGAAATTGGGTTCTTTCTACTTTTTGGCTATTATGAACAGTGCTGCTATCAA CACTGATATACAAGTCTCTGTGTAGATGTGGGTTTTCATGTCTCTTGGGTATTGCTGGGA ATTGCTGGGCTATATGGAAACTCTATTTTTAACATTTTGAGGAAGTGCCAAACTGTTTTC CACAGTGGCAGCATCATTTTACATTTCCACGGCAATGTTTGAGGGTCCCCATTTCTTCTC CCTGATGCTTGTTACTGTCTTTTTTTTTTTTTTAATTATAGCCATCCTAGGGGTTGTGAA GTGGTATGCCATTGTGTCTTTCTTTAAATTATGTGGTAAAATATACATAACATAAAATTT GCCAGTTTATAGGTGCTGTGAGGAATGTTAAAAATAATTTTGCCATTTAAACCATTTCAA GTGTACAATTCAATTGAATTAAGTACATTCACAATGGATTAACCATTCCTACTGTCTATT TTCAGAACATGTTCATCATCCCAAACAGAAATTCTGTATTCATTAAACAATAACTCCCCA TTCCCCCATTTCCAGGTAACCTCTATTCTCCTTTCTGTCCCTATGAATTTGCCTATTCTA GGTACCTCATGCAAGTGGAATCAGGAATACACTAATATACAATACTTGTCCTTTTTTCAA GGTTCATCCATGTTGCAGTGTGTATCAGAATTTCACTGTTTTCAAGGCCAAATAATATTT CATTGTATGTATATATCACATTTTGTTTATCCATTCGCCTGTTGGACATCTGGGTTGTTT GTACCTTTTGACTATTGTAAATAAGGCGGCTACAAACATTGGTATACAGGCTGGACACAG TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCAGGCAGATCACGAGGTCAG GAGATCGAGACCAGCCTGGCTAACACGATGAAATCCCACCTCTACTAAAAATACAAAAAA TTAGCCAGGCGTGGTGGCAGCCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAAGAG AATGGTGTGAACCCATGAGGCGGAGCTTGCAGTGAGCCGAGATCGCACCACCGCACTCCA GCCTGGGCGACAGAGCGAGACTCCGTCTCAAAACAACAACAACAACAACAACAAAAAATT GGTATACTAGTATCTGTTTGAATCCCTGTTTTCAGTTCCCTGGGTATACACCTAGCATGG AATTGCTGGATCATATGATAACGCTATGTTCAACATTTTGTTTTCCACAGTGGCTGTACC ATTTTACGTTCCCATCAGCAGAGAGAGAGAGAGGGAGGGAGGGACATGTGTAGTTTAATG ACAGGGATATGGTCTGCATTGTTAAGACTATCTTGTCATTGTGTAAACATCATAGAGTAT ACTTACACAAACATAGATAGTATATACATTTTTTATTTATATATTTTTCATATGGAAAAC CAAATGTCCCAGCACCATTACTGAGTATCAATCATTTCCCCAACTTAATATGCAGTGTCA ATATCAAGTGCCATGTATCAGGTTTCTACATATGCTCCATTATAATCTATGGCACCACCA TTGTATATGTGGTCTGTTGTTAACCAAAACATCATTATGTGGCATATGACAATGACATAT ATGCCATCCTAATGAGTGGGAAGTGGTACCTCATTGTGGTTTTGGTTTTCATGTGCTTAT TCGTCCATTTGTATATCTTCTCTGGCCAAATGTCTATTCATGTCATTTATTCATTTTAAA ATTGGGCTATTTGGGGTTGTCTTTTTATTATTGAGTTGTAAGCGTTATTCTGTATATAAG TCCCTTATCAGTACATGATTTAAAATGTCTTTCCCATTCTGTGGGTTGTCATTCCACTTT CTTGATGGTGTGTTTTGAAGCACAAACATTTTGTGAAACTTTAATTCCAATCTATTGTGT TGCTGTGCTTTTGGTGTATCTGAGAAGTCATTGTCTAATCAGAGGTCATAAAGACTTACT CCTGTTCTTCCTTCTAAGTGTTTTATAGTTTTCTTGCTTACAGTTAGGTCTCAGATTTAC TTTGAATGAACTTTTGTATGTGATGTGAGATAGGGGTCCACATTCACTCTTTTGCATGTG ACTATCCAGTTGTTCCAGCACCATTTGTTGAAAAGACTATGCTTTGCCCATTGAACCGTC TTGGCCCCTTTGTTGAAAATTAATTGGCCATAAATATAAGGGTTTATTTCTGAACTCTCA ATTTTATTAAGCTGATTGATGTGTTTATCCTTGTGCCAGTGTAACATAGTTTTGATTATT ATACCTTTGTAGAAGTTCTGAAATCAGGAAGTATGAGTCTTCCAAATTTGTTCTTTTTTC CAAGATTGTTTTGGCTATTTTGGGTAGGTCCCCTGCTGTGCAGAAGAGTTAAACATGGCA AGCATAAATGTTTATGCTTAGAAAGGCCTTCCTGTAAGGTTGACTCTTGGGTGGCCTCTA GAAACCTAGGTTTCTGATAACAGTGGCTCACTATGCCTGAACTGTTAATACAAACAATAT GCTTTATGCAGAACACCTGTTCTCCTGCTGGTAGTCTGACATTTTGGTACAGGCTAGGCA GAGTGTGCCTACATTCTGTGCAGACGGTGCCCCAATAAAAATCCTGGGCACTGAGTTTCT AATGAACTTTTTTATGAAACGCTGTTGAGTTTTGTCAAATTTTGTTCTTTGCATCTATTC AGATGATCGTGTGTTTTGTATTCTACTAATATGGTGTATGACATTGACTTTCATATGTTG AACCAATCTTGCATTCCTGGAATTAATCCCACTTAGTCATGGTGTTTAATACTTTGCTAG TACTTCATTGAGAATTTTTGTGTCTATGTTTGTGAGATATTGGTTAGTAGTTTTCTTTTC TTGTGATGTCTTTGGTTTTGGTGCCAGGGTAATACTAGCCTCATACAATATGTTGGGAAA TGGTTCCTCTCAGTTTTTTGCAAGAGTTTGTGAAAGGCTGGTATTAATTCCTCTTTGTTT GATAAAATTCACTAGATTATCTTTTAAAGATGTTTAAAATGAAATATCTTTTACATTTAG CCACTTACTTTTCTCCCTGTTATTTTGTGTAGATCTGTATTTCCATTTGTATCACGTTCC TTTTGTATGCAGAGCTTACTTATTCTATTTATTTAAGAGATAGGGTCTCACTCTGTCATA CAGGCTGGAGTGCAGTGTGCAGTCACCACTCACTGCAGCCTCAAACTCCTGGGCTTAAGC AATCCTCCCACCTCAGCCTGCCAAGTAGTTGGGAGTACAGGTGTGCCACTGCACTCAGCT AACTAAAAAAGATTTTTTTTAGATACAGGCTAGCTATGTTGCCAACACACCTAGCTAATT TTAATTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGATACAGGCTATGTTGCTCAGGCTGG TGTTGAAGTGGCCTCAAGCAATCCTCCTGCCTTAGCCTCTCAAATAGCTGGAGCAGCCAC TGTCTGTAAGCATCTGAAGAGCTTACTCTAATATTTCTCATAATGCAGATTTGTTTGTGA TGAATTCCCTCAGCTTTCATTTGTCTGAAAAGGTTTTCAGCATTTTTAGGATATCATAGC ATTGACTTGCCGTTTCTGACAAAATGTTGCTATAATTCTTAACTTTGTTCCTCAGTATGT GATGTGTCCTTTTGTGCATAATGCTTTTAAGATTTTCTCTTCTGGGGCCTGGTGTGGTGG CTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTAGGTGTATCACTTGAGGTCAGG AGTTCGAGACCAGCCCGGCCAACCTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAA GGTTGGACATGGTGGTGTGTGTCTGTAATCCCAGCTACTCAGGAGCCTGAGGCAGGAGAA TCGCTTGAACCTGGGAGTTGCAGGTTGCAGTGAGCCGAGATTGAGCCACTGCACGCCAAG CCTGGGTGACAGAGCAAGGGTCTCAAAAAAAAATTTTTTTTTCTCTTCTTCATTCTTTTT CAGTAATTTGATCATGATCTGCCTTGGCGTGACTTTCTTTAGGTTTAGGTTTATTCTCCC TCTGGTTCATTGACTTTCTTGGATTTGTGGGTTCATAGTTTCATCGAATTTGGGAAAATT TTCACCTATTATTTCTTTACATAAAGTTTCTGTTATCCCCCTTTCTCCTTTCCTTCTGGA CTCCACGTGCACATACACTAGACTGGTATATTTCTACAGAGAACTGATTCTTTTTCATTT TTTTCATTTCATTTTGAATTATTTATATTGCTATGTTTTCATGTCTATTGATCCTTTCTT CTAGTGTCTACCCTGCTATTAGTGGATTTTTCATTTCATATATTTTATTTTTCCTCTTTA TAAATTCCATTCAGGTTATTTTTTGTATCTTTCATTCCACTCTGCATCATGTTCATGTTT TCCTTTTCATCTTTGAGTGTATTTGTAATAGCCATTTTAAGATTTTTGCTTCTTTCCTGA ACTGTTATTTCTGGGCCCTTTCCTATTGACTAATTTTTCTCCTGGTTATGGGTCACACTT TCCTGCTTCTTTGTATGTCCAGCAAAATTTTATTGGATGCTTGATATTTTGAATTTTGCA CAGGTAAGTGTTGGATTGTTTTCTTTAGAGTGTTTTGCCTTTTCAGGAACTTTTGGATGG TTGATCAAGTAGCCTTTGTTCTAGAATTAATTTAGCCGTACTTCTAATGTGTGGTCATTC TAGGTTCCCTACTAAATGCCCCTTATAGTTGATAATGCCTCTACACTCTAGCTAGAGGGA ATGTGAATTCTTTCTCATCATGAGCTCAAGGAAATGTTCATCCTACAGATCCCTACTATT CTTTCATGGTAAGTTATTCTTGCCTGGCCTCATGGGGTTTCATGTTGTATATATTCAGAT TATTCAACCAAAGAATCAAGGAGGGGACTTCTATGCAAGTTATTGTTTTGTTTTTATTTG CATACCTCTGTTCCTTCCAGGACTCTGCCCTGCAAATTCTAGCTGCTTTTGCCTCCTTGA GCCATGGTCTCTGGCTCAACTCAGTGGGATCATTAGACTCATGTCTTACAGCCTGGTGAC ACTTCCATGCAATAAGCCGGAGTGGTCTGTTCAGTGACCACAGTACTGCAACACCTGCCA ACCAGTGTCTGAAAATAGTGGCTCATGTATTTTGTCCAGTTTCTAGTTGCTTACAGTGGG AGGGTATCCTGGACTGTATTTCCCCTGCATGGTCAGCAGCGCACCTCCATTGAGTCTGCA TGTGTTTAATCTGATGGCTCTGTTGGCTGGCGTCTGTTATAGGTTATAAGTATAGCTGCC TGTGCTTCCACCACGAGCACCTGGGGTGTCTTGTGGCATGATTGAGCTAGCTCTGAAGCT GACTCCCTCTTCTCACTCCCTGCCTTTTCTCCCTTACCTTTTGCAGAAAAGGTGTGAGCG GTACTGGGCCCAGGAGCAGGAGCCACTGCAGACTGGGCTTTTCTGCATCACTCTGGTGAG CTGTGGGAGTTTTCAAGGAAGATTCCCAGGGTGGAAAGGCTTTGGGTTGGGCCTAAAAGG TTGAATGATTTAACCCACAGTCCACTCATACTGCAGGAAACCCTCTGGTGTTAGCCTGCA AATAGTTAGAACTTACTATAGGGATAGCCTTTGCATTTTTATTTTGGCTACAATCAGTTA ATCTCTGTCATGTAAATGTGCCTGGTTAGGTTGTTGAAATTCTTACTTCTCTTACCATTT CAAAAGAGCTTGGGGAACTCTCTCAAGTCATACATACAGTTAGTACTTAATAAATGCAAT AAAAGTTTCATTTTAGAACAAAAGACATCTCTTTTCATTGCAAAAGGGCTTGTGTTTTTA TAATAGTTCCTCTTTTGCTCCTGTGTCAAATGTTTCCTTAATGAAAGCTTTGGGGAAAGT TTGGGCTATATGAATTTTTAAAATGTTTTCTGTATTTGATTTTTTAATCAGGAATGCTTT GCTTTCTATAAATGTCTTCTGGTACCTATGATCTTTGTTCTCCTCCCTCTTCTTACTTGC CCCACCCCCCTTACTCAGATAAAGGAGAAGTGGCTGAATGAGGACATCATGCTCAGGACC CTCAAGGTCACATTCCAGAAGGTACTGTGACAGGGGAGGAGGAGGTAAAGGGGCTCCTGA AAGGGGAGAGGTTTCCTCTCCTGTAAAAATGGGCATCATACTAGTACCCACTTCCTCAGT TATTGTCTGGTAGACATAAATGGAAGATGCCTAGAAGTGGGCCTGGTGTATAGTAGATGG CCAATTAATGCTTTTTTCTTTTTTTTCCTAAGTCTTTTGCTCATCTTTTTCTGTGTTTCA GGAGTCCCGTTCTGTGTACCAGCTACAGTATATGTCCTGGCCAGACCGTGGGGTCCCCAG CAGTCCTGACCACATGCTCGCCATGGTGGAGGAAGCCCGTCGCCTCCAGGGATCTGGCCC TGAACCCCTCTGTGTCCACTGCAGGTTTTGGAAATGGGCTTCAGGAGGGTCTGGTGAGGC AGAGGGGACAGAGCATGGAGGGGAGTACAGGGCATGGGGCTAGTCTTGTAGTCTGAGTGC CTATTTTGAGAACCCTTGCTCACCCTCCATGGACTGTAATTGTGAGCACTTGTTCAGCAC AGACTCAGCTGGGGAATAAGCACACAGCTCTTGCTCAACAAAATGTAAGTGATTAAAAAG GTTTTCCTTGTTCAGATATAATCTGAAGATTCTGGGAATCAAGAGGCTCTGCAGGGGATC CATCAGGACCCTCACCCCCATCCCCAAATGCCCCATCTAAAAGGGGTTGTGGTCAGGACC TGACCAGGCACACTCTGATTCTCTTGTCAGTGCGGGTTGTGGGCGAACAGGCGTCCTGTG CACCGTGGATTATGTGAGGCAGCTGCTCCTGACCCAGGTACGATACAGGCATCCTGTGTG TGCAGTGTGCTGCCCATGACCACGTGTCCTGCTCAAGTGCCTTGTCTGTCTGCCCCAGAT GATCCCACCTGACTTCAGTCTCTTTGATGTGGTCCTTAAGATGAGGAAGCAGCGGCCTGC GGCCGTGCAGACAGAGGTGAACCCTGGGTCTCCTAATCTTCAGGGACAGTGGCCCACTGC TGTCATTTGCCCCTGCCTTCCCTTCTTGATGGTCCCTCACCCCAACAGGAGCAGTACAGG TTCCTGTACCACACGGTGGCTCAGATGTTCTGCTCCACACTCCAGAATGCCAGCCCCCAC TACCAGAACATCAAAGAGGTACAGAGGCTCCTTTCCCACTCTCCTGTCCACCATCAGCAC CCTCAGAGACCAGGACCCCGAGCAGGGTCCAGCCCCCGGGACTACTGGGAGCAGGCACTG ACTATGACATCCACCTGTGCCCTCCTCCAGGCATCCTTATCAGGCTCTCCCATCTTAAGC TTTCTCCCAGAGCCCCTTGAGAGGCCTGGCCAGCTTCCTCCCTCAGGAGCCTCCCCTCCT GTTTTTCTTCAGAATTGTGCCCCACTCTACGACGATGCCCTCTTCCTCCGGACTCCCCAG GCACTTCTCGCCATACCCCGCCCACCAGGAGGGGTCCTCAGGTACCCGGCTCCATCCCCG GATTCTTCCCTGCCCAATTTCTCAGGCTAACCCCTTCTTCATCCTTGGAACACCAGTCCG TTCCTTGTTCACTTCGCCAAGTGTTCGCTGGCCCTTTCTTCGAATTGAGCTCTGGGAACC CACCCCAAGATGATTCAATTATCCCAAGATGATTCATTTACCCCTTGCCTCTGCCTCTAA GGCTTGCCCTGCCTTCTGAGTTAGGCCTTTCCTGGATCCTCTAATCAAACCTTAATTCAG GTGGCTCACCCCTGTAATCCCAGCACTTCGGGAGGCCAAGGAGGGCGGATCACTTGAGCC CAGCTGGAGACCAGCCTGGTTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAT TAGCCAGGCGTGCTGGTGAGAGCCTGTAATCCCAGCTACTCCGGAGGCTGAGGCAGGAGA GTCGCTTGAGCCCGGGAGGTGGAGGTTGCAGTAAGCCGAGATCGCACCACGGCAGTCCAG CCTGGGCGACAGAGCGAGATCCTGTCTCAAAAAAACAACAAAAAAAATTCAGCAAATAAT TCTAGACGCCGCCTTCTTGTCAGGCCGCACGTTGGGTGCTGCGGACATGGGATTGAGCCG CCTTCGCAGCGGAGACTTAAGGCCCTTGTCCTTGCGGCCATCCCTTCCTGTCTTCTATGC CACTTCCGCATTCTTTTGTTCAGTAGACGTTGACACAGAAATGACCACCCCTCAAACCAA CACTCTGCCCCAAATTACCCTCCAGGCTGACCCCGTTCCTCCTTCATCCCCCTAACTTGC AGGGCGCTAGGGACACAGAAGCGAGGCCTCCAACCCAAGGAGCCCTCCCTCCCATCTAGC GCACCGCCTCGGCGGGAAGGAAGCCCGTGGTTTGCGCGCTGAGCAGCCTCCCCACTCCCG CCCTGCCCAGCGCCGCCGTTTCACTTCCTCCCGGCCCTCCCTGCCTGCAGGAGCATCTCT GTGCCCGGGTCCCCGGGCCACGCCATGGCTGACACCTACGCGGTGGTGCAGAAGCGCGGG GCTCCAGCGGGCGCCGGGAGTGGGACGCAGACGGGGACGGGGACGGGGACGGGGGCGCGC AGCGCGGAGGAGGCGCCGCTCTACAGCAAGGTGACGCCGCGCGCCCAGCGACCCGGGGCG CACGCGGAGGACGCGAGGGGGACGCTGCCTGGCCGCGGTGAGTCGAGGCTTGCTCCTTCT CAGGGCATCATCCTGCTGTGATCCGCAGGGCGGAACCATCCTGCAGTGGTCCGTCAGGCC CTGGCGGCCGCGGGGACCCCAGCCGCTAGCCTGGCCACGCCCCGACGCTGATGTCCAGGC GTCCCTGGCCACGCCCCGGAAGCGCCCCCTGGCGGTCGCAGTCGCGGTCCAGGGGCAGGG TTCCTGGCAATACTTGTCTTGGCCGCGCCCAAAGGCTGGAGGCCACGTCCGGGGTGTGTG CCTTCTCCCGCCCGGCGCCCTCGGCTCTCCCCTTCGGGCCTCCGGGGAAGCGTCCCCGCT AGGGGTGGGGTCTTGGGACTCCCTGGGGCTTCCGGAGCTGACCCGTGGGGGGTCTGCTGC CCTCAGTTCCTGCTGACCAAAGTCCTGCCGGATCTGGCGCCTACGAGGACGTGGCGGGTG GAGCTCAGACCGGTGGGCTAGGTAAGTCAGGTAGAGCCTGGGTTGCTGGGACTTTGCTGC TTTGAGTGAACCCAGGAGTCTGGGGTTGATGGGGCATGGAGCTTAGTCCTGTGGATGTGG CTGCAGTGAACCAGGAGGACCTGGAGGCGGGGGGATGGCCTTCTTCATGTCTGCCAGCTT CCACACACCTCAGCTTCTCCATGAGACCCACGGCACCCTTCTTCTCCCAGGTTTCAACCT GCGCATTGGGAGGCCGAAGGGTCCCCGGGACCCGCCTGCTGAGTGGACCCGGGTGTAAGT CTAACGCCAGTTCCTGCCTGTTGCCTCTTGTGAGCTCGGACTGCTGATGCCCCGGTGCTG CTGAGCGCCGTGCGCAGAATGGAAACAGTGGGCCTGGATCAAAGTTAAAGTTTCTCAGGG TGGGAAATGTGGGGGCTTTGCCCCAATGACTGTAGCATTCAAGGCTTGAGGCTGGAGGAG GTAGCTAGGGTATAGTGGCTGGTGAGGCTGCACAGAGCAGATTCAAGAAAGAAGATCAGG AAGGGGCATGACCCCTGAGTTATGAAGGGGAGAAGGGACAGATGAGCTTCCGGAGACTGC TCTCCTCACCACACAGCACTAGTCCATCCTCAGCACCTGAGCCTCCCTCACTTGGACACT CAGGGGACCACACAGAGAAGTGGATGGACACTTCGCCATCCAGGCAGAACTAAGCCAGGC ATAACCACAGCCAAGCAGATTAACCCCAGGCAGACCGATAAAAAGACCTCCAGATAGGCA GACAGACAGATGGACCACCAACCTGGACAGACAGCCAAAGCTTCAGAGATACAGTCCACA GGTGGACAAAGGGATCCCCAGCCAGAGAGAGAGAGACCAGCCAACAGCTTGATAGACCAG TGCAGCCAGAGAGACCACCAAACAGAGCCCCCAAAAGACAGACATCTCTGCTAGCTGGAC AGCCAGGTGGACCCCCTAAGTTAGATTACTAGACAGATATAAACAGATCCCCTGCTGAAC AGATACACAGAGTTCTCAGACCCCACCCCCACCCTCAGGTGGGCTGGCTGGCTGACAGAC CTTCTGGCCAGACAGACTCCTAACCAACCAGATGGACTGCCAGACAGGCAGACATCAGCC ACATGGAATCCTGACATCCCAGCCAGCCGGCCAGACTCTCATCTTGATGTCTTGATGGAT GGACCCCAGCTAGTCAGACATGATCCTCCAGATTGACAGACAAGTCCCCCAAATGAGTAC ACATCTCCAGCTATTCAGACAGATGGACCCCCAGCAAATCAGGACCTATCTAGGCAGACC CCAGCCAGACCCCCGCCAGACAGACTCCCAACCAGACTGACCCCTTACTATTCACACAGC CTGCCGAGTAGCTGGGACTACAGGTCTAATTTTTTTTTTTTTTAAGAAATGAGTTTTTGC CATGTTGCCCAGACTGGTCTTGAACTCCCAACCTCAAGCAATCCTCCTGCCTCAGCCTCC CAAAGTGCTGAGATTACAGGTGTGAGCCACCAGGCTCAGCCCCCTAAGATTTGAAACACT TTAAATGGCCCATGGTAGGGTTCCTGCTAGGATAAAACATTAAGCGGCTGTTAAAAGAAA TAAAAGGAGGACACGTCTCTGTGCACTGGTGTGGACAAATCTCCAAGTCACTGCAAAATG GAAAAAGTATAAGATGCTCTTTCCCTGAACCTCAAGGGTCCCGCCCCTCTCACTTTCAGG TCTCTGGACCTCTGACTGACACTGTGCCTGCCCAGGTCCCTGTATGCACTGCCACAGTGC CCTGGGCCCCATGTCCACCCCTGTCCTGCCCTTCTCTGGGATAGGGCTGGCCTTCCTCTG CCTCTGCCTGGCTGCATCCATGGTCGATCTCAAGTGCCTTGGCATGAACTCCACTCTCCT GCAGCCTTCAATCAAGGAATGATGGGGATGTGTACATACCCCACCCCACCCCTTGGCAGG GTGATGCTGAGGTGTGGATTTTTAACAGTTCCCAGACTTTCCCAGGAGGCTTGGGTTTGG GTGCCCACAGTGGGAGCTGGTGTGATATCATACCTTCGCCGGCCGCCTTTCCTTCCTGTT CTCTGTGCCCCTACTCCCACTCTAGAGCTGCCCCGTTTCTCTGTTTTCGTGAAAGAGCTG ACCCTGTGCTGCCTCCCACTCTCCCAATGCCCCTGCCACTCCTGTGAGCCTGCTGCTGGT GAGGTCGGTGCTGACCTCTGTGTTGCTGGATAATGAGTCATCTATCTCTGGAGGAGAAGA AAGGCAGGTCCTCCACAGCCCTGATAAAATCTCCAAGTCTCCCAGTTTCGGGTCCCTCTC CTGGGATGCAGACCCACTGCCTGCCCAGCTGGTACGATCCACATGCCCTCTTCTTGGGAA TAGGGGCATGGGAAAGTGACTAAAGATACTGTTCTGGCTGCTGTGTTCACTGTGAGTAAT AAACTGTCCATTTCTCCGATTCA OMIM ID 606587