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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LATS2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26524
Official gene symbolLATS2
Full nameLATS, large tumor suppressor, homolog 2 (Drosophila)
Aliases,FLJ13161,KPM,
Gene summaryThis gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q11-q12
Gene position21635722 - 21547175  Map Viewer
Gene orientationminus
Gene size88548 bp
Gene sequence
OMIM ID604861