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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AATF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26574
Official gene symbolAATF
Full nameapoptosis antagonizing transcription factor
Aliases,CHE-1,CHE1,DED,
Gene summaryThe protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q11.2-q12
Gene position35306175 - 35414171  Map Viewer
Gene orientationplus
Gene size107997 bp
Gene sequence
OMIM ID608463