Entrez gene ID | | 26575 |
Official gene symbol | | RGS17 |
Full name | | regulator of G-protein signaling 17 |
Aliases | | ,RGS-17,RGSZ2,hRGS17, |
Gene summary | | This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q25.3 |
Gene position | | 153452389 - 153332026 Map Viewer |
Gene orientation | | minus |
Gene size | | 120364 bp |
Gene sequence |
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OMIM ID | | 607191 |
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