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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL46 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 26589 Official gene symbol MRPL46 Full name mitochondrial ribosomal protein L46 Aliases ,C15orf4,LIECG2,MGC22762,P2ECSL, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq] Location Chromosome: 15   Locus: 15q24-q25 Gene position 89010633 - 89002709  Map Viewer Gene orientation minus Gene size 7925 bp Gene sequence >MRPL46:complement(3968236..3976160):Length=7925 GCGGTGCATTGTGGGAGAACGAAAGATGGCGGCGCCCGTAAGGCGGACGCTGTTAGGGGT GGCGGGGGGTTGGCGGCGGTTCGAGAGGCTCTGGGCCGGCAGTCTAAGCTCTCGCAGCCT GGCTCTTGCAGCCGCACCCTCAAGCAACGGATCCCCATGGCGCTTGTTGGGCGCGTTGTG CCTGCAGCGGCCACCTGTAGTCTCCAAGCCGTTGACCCCATTGCAGGAAGAGATGGCGTC TCTACTGCAGCAGGTGGGACTGAGATGCAGGGTTCAGAGTGACGTTTATTCTGCGTGACT TTGAGCGAGTAATTTCACCTCTCTGAACTTAAGTATACGGTACTTATCCGCAGAATGGTA CCTACCTTACTGACTTGGTTTGGTACATAGATGTTCAACAAAAAGTGGTTTCTTTTCATT GGCCGTGTTTATTGTCACCTTAGACAACTCTTTGGAGATACTCTACTTCTTGTTCATGCA ACACAATAGGGATCCTGTGGTGAACAAGAATCGGTCCGTGTCACTAGGAGCTTACAAGTC TGGAGGGAGAAAGTCTTTGTGATGTGATGAATGTTAAGAAGGAAATACAAGAGGCGGTGG GCACATCTGTCAGATGCCTATGATAAGCCTACTCTGTTTTATCTCATGGGGCTATCTGTG TGAGGGGCAAGTGAGGAAGCATGGGCAAAAACAGTGTAGTGGCTGTGAAGGTGTGAGGTC GCTACAGAAAGTGTTTGAAGGGTGATATGTTTCCTCAGAATCCGAGATGTTTTTGTCTTG GTCTGTTGAGAACTATAAACTTCTCTTCTGTGCTTTTTGCTTGATTTATTCATTTACTCG CTCGCTTGACAAATATTTGTTACTCAACCTACAGATGTTCATTGTGCCCATACTATGCAT CAGAGAGTATGTTAAGTGATAGAGATGCTGTAATGAATAAGGCAGAAGTAGCTCTGGTTC TCAGAGTACTTCAGTCTAGTTGAGTGAGGGGATCAGTCAGTAACCAAATAATCATACAAC TAAATGCAGACCCTGATAAGTGTTGTTAAGGAAAACACAAGGCACTATAAGAGTGTTTAA CAAATACATCACATTTTGATTTTATGGTGAGTGTCAAGGAATGCCTCAGACTTTCTGAAT ACAGGTTTTTCTCTTTATGAGAAATGTCTCTCTGAGACAGTCATATTTAAATTGAAATCA GAAAGATGAGTAGGACTCTCCCAGAAGAAAGAATGTGAGGAAAAACATTCTAGGAAGAAG GAACAACCTCTTGAAAGTCCCTGAACAGGAAAGTCCTTGGTGAGTGAGATTCTGATCAAA GACTGACATGACTGGATTGTGGTGAGTCAGCAGGCATTGCCCAACCCAGCTCTCTGTTTT TGTAGCACTCTTGACCCCCAGTGACATTGTAACATTTTTGGCAAATGTAACTCAAGCCCA AAGTTCAGAGGACCTTTTTTTCCCTCCATTTCCTTTCTGCATGGTGTTTTGACTGTGTAT CTGGTTATGTTGGGTGATAAACTTCTGAGCTTGCCAAGTGTGCCATGTCTCTGTTTTATT CTTCCTGTTTTTTTTTTCCTTTTAATTTTGCCAGATTAAGGTAGTTTTTTGCCCTTTGAA TTTTCCCAGATTGAGATAGAGAGAAGCCTGTATTCAGACCACGAGCTTCGTGCTCTGGAT GAAAACCAGCGACTGGCAAAGAAGAAAGCTGACCTTCATGATGAAGAAGATGAACAGGAT ATATTGCTGGCGCAAGATTTGGAAGATATGTGGGAGCAGAAATTTCTACAGTTCAAACTT GGAGCTCGCATAACAGGTTGTGATCCTTTTAGGCCAGCCAGAAGGAAGGGAAAAGGGGTA TTTGGATTCCCAAATAAAAGACAGTTGCTTGGCCCCTGCTTTGTGTTTTAAGTAACAAAT AATTTCATATTCTTTTCTTTGTTGCTCACATCTACCATAATACGACTTAAAAAGTCTGTC TTATTTTCGGGTGAGAGGTAAGGGTATTGGAATAGCCTTTTCTCTCAGTTAAACTTTGTG AATGTTATCTGTGTTTAACTCCAAGTTTGAGACTGAGAGTGGGGCAAATGAAGCCTTTTT CCACTAATTCCTGTGTTTTATGTGAAATCCCTCTTAAAGCGGGAGATTGAGTTCTGTTTT CCTTGTTTCACAGATGAAGACTGAAGAACAGAGAAAGTAGGGGCTAGTTAAGTCAGTAAT AGTATCAAAACCAATGAAGTAGTTGTGTTTGAATTAGTATGATCATTGTTTCTTTTTTGA AGACTCAAAATATGGTTTGCTGTTCAAAGAAGCTTACCTCTTGATTTCTTACCTTTTAGT TTCCTCAAGATTGTGAGACTCTTCCCTGGAAGAGGTCAGAGTTAGAGAGATGGGTCGAGG TGTAATTTGGTTCTAAGCTCTTTGAGGGCAAGGATTGTGGATCTTAAAGGAAGATTGTAA AACTCCAGGTTTCTTGGTTCTGGCAGATCACAGTCTTCTTACCTCCTCTGACCCCCTTTG CTGTAGAAGCTGATGAAAAGAATGACCGAACATCCCTGAACAGGAAGCTAGACAGGAACC TTGTCCTGTTAGTCAGAGAGAAGTTTGGAGACCAGGATGTTTGGATACTGCCCCAGGCAG AGTGGCAGCCTGGGGAGACCCTTCGAGGAACAGCTGAACGAACCCTGGCCACACTCTCAG GTGGGTTTTCTGCCTTCCTCTAAATTCCACAAAATTCACTTCAGACTCAGCCAGAGGATT TTTAGGCTGACTGGGGAATTGGATTAAGGGTGGGGGTGGGAAGGTTAATGGAAATTTTGA AGTTTATAAAAATTTCAGCCAGAAAAACCCAGGTAAGGATTTTTTTTATTTTTTTTTTAT TTTTATTTTTAGACCAGGTGAGAATCCTTTGTTCCACTGAGATTTTAAAATTTAGTACAT TCAAAATTGATATTTCTACCATTTTCTCAGCCTGCTTGTCTTCTTATCTTTGCAGCACTG CTTATTGCCATCACTGCTTATCTGTTCACTCAACTTGAAACCTCAGAATTGTCCTTGACC TCATTCCCACATCCATAAGTCCTTGAGTCCCTCGTGATCTGTTCTAAATAGTCCCCTCTT TGTTCTAACAGCTTTAGCTGTGACCCTCTTCACTTCTCACTAGACTAGGGTTTCCCATCT CTGGCATTATTGGTGTTTGGGGTCGGATAAGTGTGGGGAGCTATTCTTTGTGTTATAGGA TGTTTAGCAGTATCTCTGGCCTGTACCTACTAGATGCCAGTAGCACTACCTCATCCCCTG ACCCCACCCCCAGTGCAGTAACCAAAAATATCTCTAGACATGGCCAGATATTTCCCAGGG AGCAAATTACAGTGGTTGAGAAGTACTATACTGAGCTATTGAATTAGATGCCCAGTAAGT TTAACCTTGGTTTTGTGGAGTGCCCTTCAGTGCTGCCAAAATGAGCTTTCTGAAACACAC ATCCCTTGTCACTTCTCTGCATGGAATTCTTAAAAGGTTTCCAATAAAAATTCTAACTGT CAAGCATGGCCTGCAAATCTTATTTGCCCTGATCCCAGTCTCATCAGTCTGCCGTCTTGC TGTTCATTAATGTAAAATTCAAGTTCTAACTTAACAAACCTTTTGCATTCCTTGAATAGT ATGGTCTTTCATGTGTCTCTGCTTTGGGGCCTGCTGGTCCCTGATGAAATACTTTACTCC TTCCTGGCCTGACTGCTCAGTTTTTAAGACAGTTTATACATTATACCGTATGTGGTGAAA CCTTTCCTGAGCCTTCAGGAAGACAGAGCTACTCCTCTCTCTAGGCTCCCGTAGCACTGG TGTGTGTCCTTATTCCATTTATGCAACAGACATATAGGGTCTCAGTGATGAACAGGACAC TACCCTACTCCCTAGGAGCTTGTGTTCTAGTGGAGAATACATTCTTTCACTTATGCCATT GCACTATAATTGTTTACTAACACATTTTTCTCCCTAGTCAGAATTTTGACTTCCTTAAAC ATGTGGGCAGTATCTGTTCCTCTCTCTGATCCTAGCTTTCAGCAAAGTACCTGGCACATA GGCATTTGTTGAATGTTGACTAAATGGATTTGGTGGTGCACAGCCACTTTACCTGCCCTC CCATCAGCACAAGTACCTGCTAACGAAATGTCGGTAGCCAGTGTGTGTTCCCTTGACTCT CCCAAGGGGCCTGTGTGGCCTGCAGGAGAGACATCAAGACAGAATGGAATATGGTAGGAG AGGAGGTTGCTGCTTTCTCAGTCTCCTCAGCCATCACATAGGAGTCAGCAGCTGAGTTTC TTGCGAGGATCATTGTGTCCAGATGCTCAACGTCTCTTAACGTCAAACATTCACAACTGA TCCTTGCTCAGCTCCCCTTTCTGTTTGCAGTGAGGAAAGGGGTTCTACCCAAGCACTATG CTTTCCTTTAAACATTGCCATTGTAATAAGTAAATGTAAAAGGAAATATATCAAATATAT TAAAACACATATTTATGTTTAATAGATGCATATAAAATAGTGTATTGACTTATTACAAAT TTACTAAACTGACAAATAATATAAAATGGCAAAGAAAAACTCAAGCAATGTAAGAGTATA TACTGTATATTTAAAAAGTGAAAGTGCGCTCCTTTCCTCCCCTCTGGCTCCACACTGCCA GTATTTCTGCAAGATGGAATTTCTAGCGGTAGAATTAATGGGTCAAAGATGTGCACACTT CAGTTTTTGGTAAGTGCAGCCCAGTTGCCCTCCAGAATGTATATAACAATTGACGTTTTC CAGGAGTGGTGTCTGAGAGTGCCTCTTTGTCTAAACCTCACTGACACATGAAATAGTTGC TTTTAAAATTTTGCTCGTCTAGTGAGTCAGATGATCTCTTTCAGATTAGCATTTTCCTGT TTGCTAGTGAGATTCAGTATCTTCATGTGTTTATTGGCTGTTTGTACTTCTTCTTTTGTG AACTGCCTATTTAGATCGTTCGCTCATCTTTGTAATAAGCTGTTTTTTCTTTTTAATTTG TTTATATTTTTAATCCATCTTTTCCAGATTATAGAAAAGTAACATGCATTTATGGGATTA AGTTTAGAAAATTCAGGAAAGTGTAAAGAAATATGCCAATACAATTCCACCACTCACAGA TACCCACTGCTAACGTTTTTTACTTTATGTGAGCTCACACTATCTATAAATTTTTCATCT AATGCTAGGTAGTGTTTTTTTTTTTTAGTATGAGAAAAGCCATTCACGTATGTGGTAAAA AAATTATCGGTGTCTCGTAAATGTAGTGTAAGATGTAATTTTCCTTTTTCAGAAGCAACC TCTATTAATAGTGTTTTTCTGTATCTCTTCAGAAATTCTCTATGCATATACAGATGCATA AATGTTTTGTTTTCTTTTTTTGCATATAACGGGAACATGTTTATACACTGTTGTGTGCCT TCCTTTTTTCTCATATACGCTTTTAAACATCTTTTCAGGTCAGCCTATTAAGACCTATCT TAAGCTTTTTTTAACACCAGCATACTATTTTATAATATGTATGTACTGCAGTTTGTTTAG CCAGTCTGTTTTTACAAACAAAGCTGCAGTGAATATCCTTGTATGCTCATCTTTGCTCAC ATGGGCAAATTAGTATATCTGGTAGGATAAAAGTCTAGAACTGGAGTTGCTAGGTCAAAG GGCATGTGCAATTAAGTTGACACCTCTTGCCAATTAATAGCACTTATACTAATTTATAAC CCCTCCAAAATATGTGTGAAAGTACAGGTTTTTTCCTTATCCTTCATAAGCAGAGTACAG TTAAGTTTTTGAACTTCAATAATGATATATGTTGTTGTTTAACTTTATTTCTTTAAATTA TTAATAAGTTTGAACACCTTTTAATGTATTTATGGGCCAGTGATATTTATTTTCATGTGA GCTTAACTGTTCATGTGCTTGGTTCATTTTTCTTTTTAATTTGTTGTTTTTTTTCCTCAT TGATTTTTTTTCCTTTAGAGATGGAATCTTGCTATGTTGCCCAGGCTGGCCTTAAACTCC TATTCTCAAGCAGTACTCCTGCCTCAGCTTCCTGAGTATCTGCATTGATTTTTAAGTGCT TCTTATACCTTAAGATATTCCTTTGTTGAACGTGTTGAAAATATTTTTCCTAGTTTGTCA TTTTGTCTTTGACTTTTTTTGTGCTTCATTTTTCCTTGCAGAAAGATTTAATTTTTATGT AGACAAATATAAATCTTTTGTTTTTTGGGCTTAAAAATTTTGTTTCTTGCTTAGAAAGGC CTTGCCCTCTCAAATAATATCTTAAGGTTTAAGAAAGCATCCTGCATTTTCTTCTAATGC TCATGTGTTTTTATTGTAATTAGAAAATATGCCCTGCACTTTGGGAGGCCGAGGTAGGCG GATCACTTGAGGCCACAAGTTCAAGACCAGCCTGACCAACATGGCAAAACCCCGTCTGTA CTAAAAATACAGAAAAAAAATTAGCTGAGTGTGGTGGCACATGCCTGTAATCCCAGCTAC TCAGGAGGCTGAGGCATGAGAATCCTTTGAACCCAGGAGCCTGAGGTGGTAGTGAACCAA GATTGCACGACTGCACTCCAGCCTGGGTGACAAAGCGAGACTCTGTCTTGGGAAAAAAAA AATACAGAGAAGATTGGAAAATATTAAATGTCCATGAAACAACCATCCAGAATGAATAAA TTTTTTATGAAAAGTTAAAATGTCTATTGTTAAATCTTTGATCTATATGGTATCAATTTT ATTGTGAGGACTGAGTATGGAATCCAGCTTGGTTTTTCCCATCTGGCTAATCAGTTCTTC AGATGCCGTTTAGTAATTAGTCCATCATTTCCCCATCATTTGAAATGCTGAATTGGGGTT GTTAACCCTTAGTTATAGATTACAGATACTGTCTACTCATCTGTTTTTGTCTTTAACTTG GTTTATGCCTTTTTTCACTAGGTAGGAGTTAAAACTGGGGTCCTTTTTAATGCTTTCCAG GTGACACCCATTTTAAAGGTGGATGAACTTTGTTTTACAGACCAAATGTCCTCGTCCTTC ACCAGCAGATAGCGACTGGGCTGATTCACCAACAGTTAGCGACTGGGCTGATTCGCCAAC AGATAGCGACTGGGCTGATTCGCCAGCAGATAGCGACTGGGCTGATTCGCCAGCATAGCG ACTGGGCTGATTCGCCAGCAGATAGCGACTGGGCTGAATGTAGGAACTAGGTGCTCTGAC TCCCAGGTGTGATTGTAACTGTGTTGCTGACTTTCAGTCTAAAAACAGTAGCTTGGCACA TGGGAGTGAGCCTGGTGAATCTGGACTCCATGGGCCAGGAGGCATTTGGATTGAGAGGGG AGGAGCCTCTTTTCAGGAATGGCTCTAGTCCTATTCCTAGGGATTGATTTTACCTCAGGG CCAGATCTTGCAGGGACCCCCTATAATTTTGGGAGCCAGAGTAAACAGATGGCTGTATCC TTACCTTCCAATTGTGATTTTTCTTTCCTCCCTCTTCAGAAAACAACATGGAAGCCAAGT TCCTAGGAAATGCACCCTGTGGGCACTACACATTCAAGTTCCCCCAGGCAATGCGGACAG AGAGTAACCTCGGAGCCAAGGTGTTCTTCTTCAAAGCACTGCTATTAACTGGAGACTTTT CCCAGGCTGGGAATAAGGGCCATCATGTGTGGGTCACTAAGGATGAGCTGGGTGACTATT TGAAACCAAAATACCTGGCCCAAGTTAGGAGGTTTGTTTCAGACCTCTGATGGGCCGAGC TGCCTGTGGACGGTGCTCAGACAAGTCTGGGATTAGAGCCTCAAGGACATTGTGTGATTG CCTCACATTTGCAGGTAATATCAAGCAGCAAACTAAATTCTGAGAAATAAACGAGTCTAT TACTG OMIM ID 611851