Entrez gene ID | | 26986 |
Official gene symbol | | PABPC1 |
Full name | | poly(A) binding protein, cytoplasmic 1 |
Aliases | | ,PAB1,PABP,PABP1,PABPC2,PABPL1, |
Gene summary | | This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes. |
Location | | Chromosome: 8 Locus: 8q22.2-q23 |
Gene position | | 101734315 - 101715144 Map Viewer |
Gene orientation | | minus |
Gene size | | 19172 bp |
Gene sequence |
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OMIM ID | | 604679 |