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Gene information for PABPC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26986
Official gene symbolPABPC1
Full namepoly(A) binding protein, cytoplasmic 1
Aliases,PAB1,PABP,PABP1,PABPC2,PABPL1,
Gene summaryThis gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
LocationChromosome: 8   Locus: 8q22.2-q23
Gene position101734315 - 101715144  Map Viewer
Gene orientationminus
Gene size19172 bp
Gene sequence
OMIM ID604679