| Entrez gene ID | | 27 |
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| Official gene symbol | | ABL2 |
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| Full name | | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) |
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| Aliases | | ,ABLL,ARG,FLJ22224,FLJ31718,FLJ41441, |
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| Gene summary | | This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 1 Locus: 1q24-q25 |
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| Gene position | | 179198819 - 179068462 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 130358 bp |
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| Gene sequence |
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| OMIM ID | | 164690 |
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