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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DKK2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27123
Official gene symbolDKK2
Full namedickkopf homolog 2 (Xenopus laevis)
Aliases,DKK-2,
Gene summaryThis gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq]
LocationChromosome: 4   Locus: 4q25
Gene position107957453 - 107842959  Map Viewer
Gene orientationminus
Gene size114495 bp
Gene sequence
OMIM ID605415