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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYTH4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27128
Official gene symbolCYTH4
Full namecytohesin 4
Aliases,CYT4,DJ63G5.1,PSCD4,
Gene summaryThe protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q12.3-q13.1
Gene position37678495 - 37711389  Map Viewer
Gene orientationplus
Gene size32895 bp
Gene sequence
OMIM ID606514