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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for INVS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27130
Official gene symbolINVS
Full nameinversin
Aliases,INV,KIAA0573,MGC133080,MGC133081,NPH2,NPHP2,
Gene summaryThis gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q31
Gene position102861511 - 103063426  Map Viewer
Gene orientationplus
Gene size201916 bp
Gene sequence
OMIM ID243305