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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL37 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 27178 Official gene symbol IL37 Full name interleukin 1 family, member 7 (zeta) Aliases ,FIL1,FIL1(ZETA),FIL1Z,IL-1F7,IL-1H,IL-1H4,IL-1RP1,IL-37,IL1F7,IL1H4,IL1RP1, Gene summary The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] Location Chromosome: 2   Locus: 2q12-q14.1 Gene position 113670548 - 113676459  Map Viewer Gene orientation plus Gene size 5912 bp Gene sequence >IL1F7:3419211..3425122:Length=5912 CTTCATTCCATTTTCTGTTGAGTAATAAACTCAACGTTGAAAATGTCCTTTGTGGGGGAG AACTCAGGAGTGAAAATGGGCTCTGAGGACTGGGAAAAAGATGAACCCCAGTGCTGCTTA GAAGGTAAGGTTCTTGTAGAAATCTACCTCAGGGCCAAAGTGTAATTCCTAGAGCAGAAC TTTGCTAGGTGCTGTGCACAGACCCAGTTGTTTCCTGCTGACTTGCACAGTAAGTGAGCT TTCAAATTTCCCTGGACAAATAACTAGACAAGAGAAATTCTGGAAGGGAAAAGGAAGCTT TGCTTCAGTGTCCAGGCACATCAGGTAGTAGATAAAAGGATCGTCCTCACCTACAGATTT GGGGCTTTAGCATCCTGTTTGCCAACTGGATGGTTGCATATGCTTCAAAATGCACCTCTT CCCTCCCAACATTCCCAAGTGGAAGAGAAGCCTCCGATGAGAAGCAGCTCTCTAAGGCTG GGCTGAACAAATGACCCAGGCACAGGGCATCTGAGTATTCCATGAGGAACACATTTGGGT GTTGCCCATGGGGGACAATAGGAGGAGGCTTTTGACCCAAATGATTGTCTACTGAGGTGT GACGGGAGAGGCCTGTGACATGCCAGAGGCCAAACCCGTGATCCAGTTCATCTCTATTCT ATGTTTCTGAAGAGGGAAGCTATGATTTAATGTCATTACTATCATGCTGCTCTAGTATTT CTCAGCACATACACAGAAGAGGGAATTAAATGGTCTTTGATACCCCTAAATCCTTGGAAA ATCCGAATTGCATATGCTAACCTCACTGCGTCTGACTGCAGACCCGGCTGGAAGCCCCCT GGAACCAGGCCCAAGCCTCCCCACCATGAATTTTGTTCACACAAGTAAGGCCTCGGGGTG AGGTGATGGGGGTGGCTGAGGTGCGAGGGTGGGGATGGGGGATGGAGCCATTGGGTCCTC TTACAGGGTGGGAGAATTGTAGAATGGGGACACCTAAGGGTGCTGGATGGGGCTGAAGTC TTTCCTTTGTGGAAGCAAATCCCATTAGGAGATAACTCTGGGAAAGATGAGCCCGGGGAG GGGCAGGTGATGCTCACCTGCTAAGAGGCACAGGGCAAGGAAGAGTTTGTGCCTGGGAAC CTTCCAGGTGCCTCTTCTGACCATAGCCAAGAGACTGGAGACACAGACCTCCTCCCAGCA CTGAGGACAAACAGCCATGGGGCCAGTGGGGGTGCAGGGACACCCACACCACTAAGGGCT CAGGGCGGCGCCTTCAGAGCCTGAACCTTCCTCTCATGCTGCCATTTGAACACCACAACA CCCTAATAGGAAACTGTTAACATTGCCACTGTTCAGGTGTGGAAACCGAGACAGACAGTG GAGATTCCCTGCCCTAGGTGACACAGGTAATAAGTGACAGATGTGGAAATTTAAAGGTAC TATAACGTCTGTCTGCCTGACTCAGGCTTAAGGCTCCCATCACCTCCTCTTCTCAGGACA GAGTCAGGAGGCCTCAGCCTGAGCCCCAGCTCTAGTGCAGGTTCATGTGGGAATACTGAG CCTCACTAGTACAATGGCAGAGAGGACCAAATGGGACCAGGTGTGTAAGGGTGCCTGGCA CAGTTGGGGGAGGCTGCTGTCACTTCTCCACCGCTGCTGCTGCAGTTACCTTTGATGTTT TAGTTTTGTTGTAGTTACACCATTGCTGGCTTTGGATCTGCACTGTGTCCACTCCAGGTG GAACCACGCACACAAGCCTCTCTGTCGGGCCTGTCCTGACTTCTCCTTGTCAGGGCTGGG ATCTCCTTCAAATCTGGCGGAAGTGGTTCTCCAAGTCTGGTCCTCAAACGTCAGCAGCAT CAGCGCCTAGAAGTGTTAGGAATACACATTCCCAGGCCCCACCACAGACCTCCTGCCTCA GAAACTCAGGGCGCTGAGGCTCTAGGGGCTGCTTTAACAAGACTTCCAGGTTATCGTGAC GCACCTTGAAAGTCTGAGAGCTACTGCCCTACAGAAAGTTACTAGTGCCCTAAAGCTGGC GCTGGCACTGATGTTACTGCTGCTGTTGGAGTACAACTTCCCTATAGAAAACAACTGCCA GCACCTTAAGACCACTCACACCTTCAGAGTGGCCTTGAGAAAGATTTGGGGTCAAGGATC ATGAGCGAGAACACCACTTAAGAGGATAGTGAACTAGTCTGCATGTGAGACGCTGAGATC CTATGTCAGGCTGTGATAGGAGGGAAACAGAAACCAAAGGAAAGAACAGCTTTAAGAAGC GCTTAAGAGGTACAAAGTAAAATGATGGTGCTAGAAAAGTAGCTTCTTAAAAAGAGCATT TTCCAGTCTCACCCTGGACTAACTGAATGAGAATCTCAGGAGTGTGAGGCCCAGGTATCC ATGGTCTTAAAATGCCACCCACCAGGTGATTCCCAGTGTGCACCAGGGGTGAGAGTCACA GCCTTAGGCCATGCCACTCAAAGGGTGTCTTCAGACCAGCAGCACCCACAGCTCTGGGAG TGCATCAGAAAGACAGAGGCTTGGCACCACCCACACCTACTGAACCATAGTTTGCAGGTG ATTTCTTGCACATTAAAGTGTGGGAAATGGAAAAGCTTAGAGTTCAGCTAGCTCGGTGAC TCTCAGTCAACCTGCACCTGCTCCATGAACTCAGACTGCCTGGGATGGGCCCAGAAAAGC TCCTGAGGAGATTCTGATGTAAGGCAGGGCTGATAACCATGGATCTCATCTGACCCCATA TCACTGGGGAGTTACTTAGGATCTTGCCTGGGGCCAGTCATCTCTTCCATAGACACTGAG AGTGTCCACGATGCTTGGGGCACTACAGGGTGGGAGGTGGAGGATCACGGGTGAGTCAGA TAGGAAGCCTGCTCCTGGGGAGCTTACAGTGCTATAGGGCAGCGAGCCAAGGATGCCAAT ACCTGTGTGCAGGTACCACTGACGAGTGCAGAGCGCTGCAGCACCAGAGAGGAAGCTACC CTGTGCAGAGGGGGCTGAGGAGGGCTGCAGGGAGATGACAGGAAAGCCGGTGTTACAGGA GGAGTCCTCCCCACTCTTTGGGCATGAGGAGACCAGGAGGACATTCTACAGTGAGAAACC CAGGCAGAGGCCATGTGCTTATGGCATGGGAAAAGAATGACACCTTAGACTTATTCTCTA CATTAGAATTGCCTACCACAGATACCCATATTATAGCTTCACATAGTGTGGTGGTTACTG TGTTTTCATATTGTCACATTTGCCATTTTCCAGCCACCCACCCATTCTTGACAGTCACTG GCCCAGCCTGGGGGCCCCTGTTCTTTATCAAACAAGTGCCTGAGCTCTTTGCAGAGGTGA GGGTCACCTGTCCAATCAGAGGCCAGGAGGGAACGTTCCCTTTTAAGACCCTACTCTAGG CAGGCCTGGCCCAAATGAGTTGCTAGGAGCCCACGCCCTAAGAACCCTCTGAGCACTGTT GTGGCTGGTCCTGCTGCTAGAAGTTGTTCCTCCAGGGCCAGGTGCAAGATTTGTGGCTTT TCAAAGGAGCCACTAAAGCTCCAGCTCAGCCTTGCACCGTGCTGGGCTCCTGGGGGCTTC CTGCCTCCAACCCTCCCAACTCTTCCATCACCGCTCCCTTAGCCTGGCCAGTGCAGGGAT CTGTTCCACTCTAGGCACTGCTGAGGGAATGATGCCTCCAGTCAGAGGGTGCAAAAAAGA GAGTTAAGAAAAACAATGATTATAAAAAGTCCTTTTTATACGCCAGACATTTTCTTTGCT CAGGCTAAGTGCTACTTATTTGAGTAAGCATTTTAGTTCTCATAACTCCTCTCTCAAGTA GGTGCTGCTATTACTTTCATTTCACAGATGAGGACATTGAGGTTTGGAGAGACTTAGTAA CTTGTCCTCTGTCCTACAGCAGAGCTGGGATTTGAATCTATCTGTCCAAATCTGGAACCC ATTTGCTTGCACAGAAAGCTTAATTGCTTGTCCCAGCAAGATAGAAAGCCTGGGAGTGGA AGAAATATTCAGTGGCTGTGATGTCTGAGCCCACAGGCAGGGTGGAGAGCTAGGGCTGGG GCCCTTGGACGTGGGGAAGAAAGGGCTGAGTCTTCCATTTTCAATGTGAAGTGTTGATAT CTGGTGATATTGATCTAGGTCCAAAGGTGAAGAACTTAAACCCGAAGAAATTCAGCATTC ATGACCAGGATCACAAAGTACTGGTCCTGGACTCTGGGAATCTCATAGCAGTTCCAGATA AAAACTACATACGCCCAGGTGACTCTCAGTTTTGGCTGTGTTTTCTGCCTCCACCTAGCA GGGGTAAGGCCTCCTGCTAGGTGGGCTCAACTCCATGCTATACCATGCCCCATCTCCAGC AGGTGGTGGAAGCGAGGAGGAGAGGCCCCAGGGACTAGGGCATCAGATGAAGGGTCTCTA GCAATGACCAGATCTGAAAGTAGTCTTTCTGGAAGGGCTGGAGAAAAAGAAGGAGGCAGA CACTTAGACTGGAAGAAGAGGAGGCTTAAACCAGTGTGATGGAGGGAGAAGTGGACCACA GAGTCAAGGGAGAGGGACTGTGCATCAGGCCTGAAACCCCAGCAGACAGGAGAGACCTTT CCCTGCTCTCAGAACCCACACATGTTCTGACTGTCTTTTTCCAGAGATCTTCTTTGCATT AGCCTCATCCTTGAGCTCAGCCTCTGCGGAGAAAGGAAGTCCGATTCTCCTGGGGGTCTC TAAAGGGGAGTTTTGTCTCTACTGTGACAAGGATAAAGGACAAAGTCATCCATCCCTTCA GCTGAAGGTGAGAGTTCTAGCTCAGTTTCCTGGGCCTTTGGCTACCCCAAAGTAAAAGGC CAAGATCCTCAATGCCTCTCGCTTTCCTGCAAATTCTTATCTTGGCCAATATAACAGGGA CATCCACCTTTCTGGAAGCACCAGGCAGAAGAGCCCCATAACTTCTTCTCTGGTTCCTTG CCCCTTCTAGGGAAGGAGGAGAGACTCCTCACAGCGGGGAGACAGCAAGGAGCTGAGCAC CTGTTCTCCTCTCCTGGGCTCACTGGTCCTGGCCCTGGGCGGGTGGCGGTCCCCTCCTGC TGTGGCCCTCCATGTGGCAAGCAACACAATTGGGCCAGGACCCTGGCGTGCTGCTGTAGG GTAGGAGGGTGTGAGGGAGCACTCGGAGGGCAGTGTGTCTGCCCTGCAAATTTAGTCCTG GATGGAGCACCTTTCACTTGAGGGGAGAAATCTTAGGAAGCTGAATTAGATACAGATCTA AGCCATATTCTCTAATTTTAAAAACTATAGAGCTGAGATTTTGGTATCCATCTGACTCTT ACGTCTCTCTCTCTCTCTCTCTCTCAGTTTATTTTTAATCTGGGGGACAAGAAGGCCTGG AAAAGAGGGCAGGATTGCTTATCATCCCTTAAATACCAGTACCAAGGCTGACACGTCATC TTTCCCAAGGACCATCTGCCTTCTCTCTTTTCCTCCTCTCCTGTGTAAAGGCCTGGAGGA TGAGCACATGTGCTGTGTTTTCCTCCCTCTCAAAGCCTGTGCTATCTAATTAATCCCTTT TACCTCACAGAAGGAGAAACTGATGAAGCTGGCTGCCCAAAAGGAATCAGCACGCCGGCC CTTCATCTTTTATAGGGCTCAGGTGGGCTCCTGGAACATGCTGGAGTCGGCGGCTCACCC CGGATGGTTCATCTGCACCTCCTGCAATTGTAATGAGCCTGTTGGGGTGACAGATAAATT TGAGAACAGGAAACACATTGAATTTTCATTTCAACCAGTTTGCAAAGCTGAAATGAGCCC CAGTGAGGTCAGCGATTAGGAAACTGCCCCATTGAACGCCTTCCTCGCTAATTTGAACTA ATTGTATAAAAACACCAAACCTGCTCACTAAA OMIM ID 605510