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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for C5AR2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27202
Official gene symbolC5AR2
Full nameG protein-coupled receptor 77
Aliases,C5L2,GPF77,GPR77,
Gene summaryThe anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM]
LocationChromosome: 19   Locus: 19q13.33
Gene position47840371 - 47845272  Map Viewer
Gene orientationplus
Gene size4902 bp
Gene sequence
OMIM ID609949