Entrez gene ID | | 27242 |
Official gene symbol | | TNFRSF21 |
Full name | | tumor necrosis factor receptor superfamily, member 21 |
Aliases | | ,BM-018,DR6,MGC31965, |
Gene summary | | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.1-p12.2 |
Gene position | | 47277680 - 47199268 Map Viewer |
Gene orientation | | minus |
Gene size | | 78413 bp |
Gene sequence |
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OMIM ID | | 605732 |
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