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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GLE1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2733
Official gene symbolGLE1
Full nameGLE1 RNA export mediator homolog (yeast)
Aliases,GLE1L,LCCS,LCCS1,hGLE1,
Gene summaryThis gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.11
Gene position131266971 - 131304580  Map Viewer
Gene orientationplus
Gene size37610 bp
Gene sequence
OMIM ID603371