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Gene information for GLRB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2743
Official gene symbolGLRB
Full nameglycine receptor, beta
Aliases,-,
Gene summaryThis gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q31.3
Gene position157997277 - 158093242  Map Viewer
Gene orientationplus
Gene size95966 bp
Gene sequence