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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GLS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2744
Official gene symbolGLS
Full nameglutaminase
Aliases,AAD20,DKFZp686O15119,FLJ10358,GLS1,KIAA0838,
Gene summarySahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]
LocationChromosome: 2   Locus: 2q32-q34
Gene position191745547 - 191829776  Map Viewer
Gene orientationplus
Gene size84230 bp
Gene sequence
OMIM ID138280