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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AMT (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 275 Official gene symbol AMT Full name aminomethyltransferase Aliases ,GCE,GCST,GCVT,NKH, Gene summary The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; GLDC, MIM 238300), H protein (a lipoic acid-containing protein; GCSH, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase; DLD, MIM 238331). Mutations in the T, P, and H proteins have been found to cause glycine encephalopathy (GCE; MIM 605899).[supplied by OMIM] Location Chromosome: 3   Locus: 3p21.2-p21.1 Gene position 49460111 - 49454211  Map Viewer Gene orientation minus Gene size 5901 bp Gene sequence >AMT:complement(49394211..49400111):Length=5901 GAGCTGCCCTGAAGAGTCAGCCGAAAGAGCTGGAGGCTTCTTCCCTGTGGTTGCGGGTTC CTGCATTCTCTGCTCTAAATCCCAGCCTGCCCTTGGGGCTGCCCACGCCCCCTTCAGATC CTTTGCTCCGGAGAGAGACCTGTCCGAGCAGAGGCCTGGACTACATCTCCCGGCGTGCCT GGCAGTGTGGTGGCCTCTGTGCGCCGTCTGCACTCGTTGCAGGCGACGATGCAGAGGGCT GTAAGTGTGGTGGCCCGTCTGGGCTTTCGCCTGCAGGCATTCCCCCCGGCCTTGTGTCGT CCACTTAGTTGCGCACAGGTGGGATAGAGGGTGCTGATCTTGGAGGGTGGGGGAGGGAAG CGGCTGGGGGCTAGGGCCCTGGTGGCACTAAGCCCAGCCGCCCACAGGAGGTGCTCCGCA GGACACCGCTCTATGACTTCCACCTGGCCCACGGCGGGAAAATGGTGGCGTTTGCGGGTT GGAGTCTGCCAGTGCAGTACCGGGACAGTCACACTGACTCGCACCTGCACACACGCCAGC ACTGCTCGCTCTTTGACGTGTCTCATATGCTGCAGGTGAGCCAGGGGAGCACACTGGCCA TCTGATCAGGCCTTCCTCCCTGTTTACAGTGGTCCACTCCTTGGCTTTGTTTGCTGTGAA CTGGATTCCAAGGACAGCCTTCTCAGAAGAGCTAGAGGTCATGGGGGTGTCATGGATAGG TCAATGGCCCCAAGGAAATGAGCTCAGAGGGTCTCATCATCTCATCCTTCTAGCTTGCCC CCATTAAATGGTGTGCCTTAATGTCCCGGGTTTTCCAGGGCTGACACCCACTCTCATGTA TTGGGCTGGATGTTGGTTTGAAAAGGGGTTATTTCAGGAAGGTGCTAGGTCCTGTCCAGT TCCCTGGCAGTCCCCCCACACAGAGTGACTGGGGGAGGTCAGGAAATCAGAAGGTGGTCC TTTGCCACGTGTAGAACCAAAAGACTGGTTAGTCACTTTGGGTGGGCTGGACTGCACTGT GGATGGCAGGGAGGATGCATCCTTGCTTAGTAGCCTTTTGGATTGTAGCTGTTGCAATGG CCTGAGGCTTTCAATCTCTTCCCCAGACCAAGATACTTGGTAGTGACCGGGTGAAGCTGA TGGAGAGTCTAGTGGTTGGAGACATTGCAGAGCTAAGACCAAACCAGGTGGGCCCTTTTA TTTCTGCTCTATGAGTTTTCTTAGTCATGAGCCAGCAAATGGGCTGAGTCCCTACCTCAG GCTTAGGGGCACAGAGATGAGTCAAACACAGCTTCTCAGGGCTTGCAGTCTTGGACAGAA TCCCTGAGTCATTTCCAGAGACACAGACATTTGTAGGGAGGGGAATATCCCAGTCTTACT ACATCAGGCTAGGAGGCCAGAAACCAAGGTTAATATGCTGCTCTCTGGCCATCCCTTCTG CTTAACCCCTCTCTATTCAACATGTGGTCCCTGGCCAGGCGACGTGACTCAAACACCTGT AATCCTGGCACTTGGGGAGGCCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACC AGCCTGGCCAACATGGCAAAACCTCGTTTCTACTAAAAACACAAAAATTAGCCGGGCGTG GTGGCGCGTGCTTGTAGTCCCAGCTACTCGGGAGGCTGAGGTTGCAGCAAGCTGAGGTTG CACCACTGCACTCTGGCCTGGGCAACAGAGTGAGACTCAGTCTAAAAAGAAAAATAACAA CAACAAAGTGTGGTCTCTAAACCAGCATCTTTGGAGCTTGTTAGGAATATAGTCTCAGGC ACTGCTGCAGACCTGCTGAATCAGAACCTTCATTTTAACAAGATCCCCAGGTGATTCATG TGACCCCCTCAACCTCAGGCTTTTTGTCCATCCAGTGGGGAGGCTAAGGAAGTTTTTTGG GGGCATTGCTATGGAGTACTTAGGAGAGCCTGCGATCATCAAGATGACCTTTGAAGCTTT TGTCCTGTGGGTTGCCACATGGGCTAAGTCGTCCCAGGTTTGGGTAGGTGAAGCAGCAGG TCCTAGGTGTCATAGATTAAGTGTCAGATGGGACTCTCAGTACAGAGTGGGGAGGGGTGC AGAGGTTGCACCAGATCAGGGAAGCACCCCAAGGTAGGGAGGGGATGAAAACTTACTTGA TGCATGAGGATCAAAGACCTTGGACTTGGGCCCAGACTTGTACCTTGCACACCCTGAGTC CTTCACATTAGGGTTCATAACCTTTTGGTAACTAAGTGGGTCCAGGGTTGTGTCTGGCTC ACCCTTGGCCTTGCCCTCCTGGACCTGGAAGCCAAAACGCTCCACTTTGGTCCTAGGGGA CACTGTCGCTGTTTACCAACGAGGCTGGAGGCATCTTAGATGACTTGATTGTAACCAATA CTTCTGAGGGCCACCTGTATGTGGTGTCCAACGCTGGCTGCTGGGAGAAAGATTTGGCCC TCATGCAGGTATACCCCCTCTGTGTTCTAGACACCTTGTCTTCCTTGTTCATAGAGCAGT ATCCTTGTTGTCCAAGACAGGGTTGGCACAGACAAGGGACCTGGAAAATGGCTCTTTCAG TGAATGAACAGCTATGAGACTCAAGAGCAGGCCCTCTCTGGAGCACGCCAGGGTTTGGTG GTGGGGGATTACCAGGCATGGGGAGGGGGTCTTGGCCCCTCTGGTGTGAGGTGGCAGAAC TGGGCTTGGGTCATCTCTATCACTTAGTAGCTATGTGACCTTGTAAGATGGGAACCAGCC TACTACCTTTTTTTTTCCTCCCTCCTCCTCCTCCTCTCCACTGTCCTACTACTGTCCAGC TCTGCAGCGTCCAGCCCATGGTAGCTGCTCAGTAAGTGGCCCCAGATGCTCTTGTGTTTC TGTCTTTTAGGACAAGGTCAGGGAGCTTCAGAACCAGGGCAGAGATGTGGGCCTGGAGGT GTTGGATAATGCCCTGCTAGCTCTGCAAGGTGAGAGGGCTGGGCTGGGGTTGGAGCCAAC CTTTGCCTTCCTGGCTTCATTGACTGCTTAGCACAGAGGCCATACCAAGAAGAATGTGTG GAAGGTGTGATATTTGTGTGCCATAATTTTAAGTTTTGTATCTTGCCCTCCTCCTACCTA CCACAAGGCTCCATGGGCTAGGGACAAGGGCATCTTCTCCCACTTGCAGAGTAAGACATG CTCAGGGCTTGTTCTGGTCCCTGAATAAGGCTTTAGTCCAGCTTTGAGGGATGCTGGGAC CTGGATACTTGGTCACTGGCTCCCTGGGCCCAGGCCCCACTGCAGCCCAGGTACTACAGG CCGGCGTGGCAGATGACCTGAGGAAACTGCCCTTCATGACCAGTGCTGTGATGGAGGTGT TTGGCGTGTCTGGCTGCCGCGTGACCCGCTGTGGCTACACAGGAGAGGATGGTGTGGAGG TGTGTCAAGAAGTGGTGTGGGGGCAGTACAGGGCACAGGATGCATGTGAGGGGTTGGGGG TATGTGGTACAGGGAGCTTCCCATCTGCCCTCTGGTGTTTCATACAGATCTCGGTGCCGG TAGCGGGGGCAGTTCACCTGGCAACAGCTATTCTGAAAAACCCAGAGGTGAAGCTGGCAG GGCTGGCAGCCAGGGACAGCCTGCGCCTGGAGGCAGGCCTCTGCCTGTATGGGAATGACA TTGATGAACACACTACACCTGTGGAGGGCAGCCTCAGTTGGACACTGGGTGAGCTGGGCC AGCACTAAAGGATAGGGTCCTGGAGGTCAGGGTGACCCTTGATAAGACTAGCCAGCCCAT GACTCATCCAAAGGTTATGTAGCCTGAAGCCTTCCTGAGCCTCCCTTCCCTGAAGGTGCC ACTGTGCCTTTGCCCATTAGAAACTGCAGATGTTGGCCGGATGCGGTGGCTCACATCTGT AATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGATCAAGACCAT CCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAAAAATTAGCTGGGC ATTGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGA ACCTGGGCGGCGGAGTTTGCAGTGAGCCGAGATTGCGCCACTGCACCTCCAGCCAGGGCG ATAGAGCGAGACCCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGAAACTGAAGATGCTG CCGGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATC ATGAGGTCAGGAATTCGAGAATAGCCTGGCCAACATGGTGAGACCCCGTCTCTACTGAAA ATATAAAAATTAGCCAGGCGTGGTGGCGGGTGCCTGTTATCCCAGCTACTCGGGAGACTG AGGCAGGTAAATTGCTTGAACCTGGGAGGCAGAGTTTGCAGTGAGCTGAGATCGTGCCAC TGCATTCTAGGCCTGGGCGACAGAGTGACTCCATCTCAAAAAAAAAAAAAAGAAACTGAA GACGCTCGGCAGGTGGGCAGCATGGCCTCCAGGGGATAGGAGGTGGTTGGTTGGCTGACG GCAGTGAAGGGAGGAATAGAGCCTGGAGTAGCCCAAGCAAAGGGGCCTTGATGCTAGATA GTGTGTTACTTGAGGACCTCATAAGGACCTCCTGTGGCCAGGGCTTCTATGGGCTGTGGC TTATGTCTCATGTGTCATTCTCCAGGGAAGCGCCGCCGAGCTGCTATGGACTTCCCTGGA GCCAAGGTCATTGTTCCCCAGCTGAAGGGCAGGGTGCAGCGGAGGCGTGTGGGGTTGATG TGTGAGGGGGCCCCCATGCGGGCACACAGTCCCATCCTGAACATGGAGGGTACCAAGATT GGTAGGTGGACCAGGGAAGCTGGGAAACCCTTGTCTCTTCCCAGGAGGGTGGGGGCACTG GCAGGGTGGTGCTGATGCGTGGCTTATGCTTGCTTGACAGGTACTGTGACTAGTGGCTGC CCCTCCCCCTCTCTGAAGAAGAATGTGGCGATGGGTTATGTGCCCTGCGAGTACAGTCGT CCAGGGACAATGCTGCTGGTAGAGGTGCGGCGGAAGCAGCAGATGGCTGTAGTCAGCAAG ATGCCCTTTGTGCCCACAAACTACTATACCCTCAAGTGAAGCTGGCTCAGGGTGGGGCTG TCCCTTCCAGGAGTTTTGCCCCTACAAGGGGTTAGTCAAGAAGCTGAGGCAGAACTCACT GGGGGTGGGCAGTTAAGGTGGAGGCTGATTCTAATTGTCTGGTTGAGGGGCCACACCACC TATTCCCCCCACCTAACTCATGCCATTCCAGCTTCCTTCAGGACCCTGCTTCTGAGTGAC GGACCAGCTCACACAATGTCTTGTTTCAGTCCATGATCCCACTGACCTACTCTTGCCTGC TGGAGGGTAATGAGAAGCTTTGGTTCTGCCATCTCTCCCACTCTGCCAGGTGCTGGCTGT GGAGCAAAGGCTCACCTTTGTGGAGAGGATAAAACCTGCCCAACCTACCTCACCATGGTT TTTCACATTGCAAAGGGTAATAACATGGGCAGTGCGGACTTAGGCTACCCCCTCCAGTTT GCTTTCCGTAAATGCAAATTGTCCTTACTGCAAGTCAGGAATGATTGCTGACTCACAGTA GGGCTGCTATGCCTGTGTGTAAACTTGGGGATGGCTGAGGGAACATAGACTCACTCTTCC ACATTCCCAAGTTGGTCTAGTGTGCTGCCCAGTAGCAAACCATGGCAGACTCACCACCTA TTCTGAGTTCCAGGGCTGCTGTAGGGCAGGGTGGGCTTCCTCCCAGACTTGCCTTACCCT GGGCTGATCTTTGCCCCTGGTATGCATTAATGGACTCCACTGAATCCTGAAAAAAAAATT AAACTTCCTTCTTACTTGCCA OMIM ID 238310