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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GP5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2814 Official gene symbol GP5 Full name glycoprotein V (platelet) Aliases ,CD42d, Gene summary Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM] Location Chromosome: 3   Locus: 3q29 Gene position 194119995 - 194115550  Map Viewer Gene orientation minus Gene size 4446 bp Gene sequence >GP5:complement(68299..72744):Length=4446 AGTTACTTTGGAGTGCAGAACCATTTCAGGTAAGGCCAAATATTTTAAACATTAGTATAG GAAATTAGAGGGCTCTTTAGTCTGTGTGTGCATGAGAAGTAAAATTGCACGAGAAGCAAT TTATGTAAAATTTCGCTTAGGAAACATTGTTTTGGCAGGTTAGTAGTATGGTGTGCATTT CCCAGAAAATTCAGTGCCGTGAGTATTACCTTTAGTTAAGCATCTTAGAAATAGTAGCTC TTTATGGCTAAGTCAGAAATACTACCCTCAAATTCTATGTGACCCTAGTTATACTGTTGA GCCTTTCTGTGCCTCTGTGCCTTCATCCTTGAATCGGGGATAATATACTTACCTCCTAAG GTTATTGTAAGGATTAAATGCATGTAGTATAAATAAAGAGCTGAGAACAATGCATGGCGT AAAGTGATAGGTATTATTATATGCTTTTGTTGGCTGTTGATTGAAGGTGTTCGCTGTTTT GGGGGTGTCCTTTAATAGAGTAACTTGGTACTGTGGAAATAGCATGATTGTGAGCAAAAG AATCAGATGGTGGTGGCTGCAGACTTTGCTGTTCCCTTCTTGACTGTTGGTTATAGCCAA TGCAGGGTAAGTTATAAAGTCAAGAGCAGAGCCGTTTTCACAATGGACATTGCTTTGTGA TGTCTGTGAGCTTGAATGTGAGAATGATTATTTTAATTCTCTATGTAAGGACTTTAAAGT ATTGGCTATTCGGTAGCTTGAAAACTCTGTAATCTCAATGCTTTAAACTGAGAGTGGAAA ATCAATAAAGCAAAAGCATGAGGCCACGCAGTGTAGAATGAGTGTCTTTTCACCACGTAG GGAAATCTGTAGTCCTAAGAAAAGAGGGAGTGAGAATTCTGGCGAAAGGATTGTGCCTCT GCACAAAGTGCAGGATCCCAGGGTTCAGTACAGGCGCGAACGCTCCTGTGTGTTGACCAC ACTCCCACGGTTGCTTTTTCAGACATGCTGAGGGGGACTCTACTGTGCGCGGTGCTCGGG CTTCTGCGCGCCCAGCCCTTCCCCTGTCCGCCAGCTTGCAAGTGTGTCTTCCGGGACGCC GCGCAGTGCTCGGGGGGCGACGTGGCGCGCATCTCCGCGCTAGGCCTGCCCACCAACCTC ACGCACATCCTGCTCTTCGGAATGGGCCGCGGCGTCCTGCAGAGCCAGAGCTTCAGCGGC ATGACCGTCCTGCAGCGCCTCATGATCTCCGACAGCCACATTTCCGCCGTTGCCCCCGGC ACCTTCAGTGACCTGATAAAACTGAAAACCCTGAGGCTGTCGCGCAACAAAATCACGCAT CTTCCAGGTGCGCTGCTGGATAAGATGGTGCTCCTGGAGCAGTTGTTTTTGGACCACAAT GCGCTAAGGGGCATTGACCAAAACATGTTTCAGAAACTGGTTAACCTGCAGGAGCTCGCT CTGAACCAGAATCAGCTCGATTTCCTTCCTGCCAGTCTCTTCACGAATCTGGAGAACCTG AAGTTGTTGGATTTATCGGGAAACAACCTGACCCACCTGCCCAAGGGGTTGCTTGGAGCA CAGGCTAAGCTCGAGAGACTTCTGCTCCACTCGAACCGCCTTGTGTCTCTGGATTCGGGG CTGTTGAACAGCCTGGGCGCCCTGACGGAGCTGCAGTTCCACCGAAATCACATCCGTTCC ATCGCACCCGGGGCCTTCGACCGGCTCCCAAACCTCAGTTCTTTGACGCTTTCGAGAAAC CACCTTGCGTTTCTCCCCTCTGCGCTCTTTCTTCATTCGCACAATCTGACTCTGTTGACT CTGTTCGAGAACCCGCTGGCAGAGCTCCCGGGGGTGCTCTTCGGGGAGATGGGGGGCCTG CAGGAGCTGTGGCTGAACCGCACCCAGCTGCGCACCCTGCCCGCCGCCGCCTTCCGCAAC CTGAGCCGCCTGCGGTACTTAGGGGTGACTCTGAGCCCGCGGCTGAGCGCGCTTCCGCAG GGCGCCTTCCAGGGCCTTGGCGAGCTCCAGGTGCTCGCCCTGCACTCCAACGGCCTGACC GCCCTCCCCGACGGCTTGCTGCGCGGCCTCGGCAAGCTGCGCCAGGTGTCCCTGCGCCGC AACAGGCTGCGCGCCCTGCCCCGTGCCCTCTTCCGCAATCTCAGCAGCCTGGAGAGCGTC CAGCTCGACCACAACCAGCTGGAGACCCTGCCTGGCGACGTGTTTGGGGCTCTGCCCCGG CTGACGGAGGTCCTGTTGGGGCACAACTCCTGGCGCTGCGACTGTGGCCTGGGGCCCTTC CTGGGGTGGCTGCGGCAGCACCTAGGCCTCGTGGGCGGGGAAGAGCCCCCACGGTGCGCA GGCCCTGGGGCGCACGCCGGCCTGCCGCTCTGGGCCCTGCCGGGGGGTGACGCGGAGTGC CCGGGCCCCCGGGGCCCGCCTCCCCGCCCCGCTGCGGACAGCTCCTCGGAAGCCCCTGTC CACCCAGCCTTGGCTCCCAACAGCTCAGAACCCTGGGTGTGGGCCCAGCCGGTGACCACG GGCAAAGGTCAAGATCATAGTCCGTTCTGGGGGTTTTATTTTCTGCTTTTAGCTGTTCAG GCCATGATCACCGTGATCATCGTGTTTGCTATGATTAAAATTGGCCAACTCTTTCGAAAA TTAATCAGAGAGAGAGCCCTTGGGTAAACCAATGGGAAAATCTTCTAATTACTTAGAACC TGACCAGATGTGGCTCGGAGGGGAATCCAGACCCGCTGCTGTCTTGCTCTCCCTCCCCTC CCCACTCCTCCTCTCTTCTTCCTCTTCTCTCTCACTGCCACGCCTTCCTTTCCCTCCTCC TCCCCCTCTCCGCTCTGTGCTCTTCATTCTCACAGGCCCGCAACCCCTCCTCTCTGTGTC CCCCGCCCGTTCCTGGAAACTGAGCTTGACGTTTGTAAACTGTGGTTGCCTGCCTTCCCC AGCTCCCACGCGGGTGTGCGCTGACACTGCCGGGGGCGCTGGACTGTGTTGGACCCATCC GTGCTCCGCTGTGCCTGGCTTGGCGTCTGGTGGAGAGAGGGGCCTCTTCAGTGTCTACTG AGTAAGGGGACAGCTCCAGGCCGGGGCCTGTCTCCTGCACAGAGTAAGCCGGTAAATGTT TGTGAAATCAATGCGTGGATAAAGGAACACATGCCATCCAAGTGATGATGGCTTTTCCTG GAGGGAAAGGATAGGCTGTTGCTCTATCTAATTTTTTGTTTTTGTTTTTGGACAGTCTAG CTCTGTGGCCCAGGCTGGCGTGCAGTGGGCCGTCTCAGTTCACTGCAGCCTCCGCCTCCC AGGTTCAAGTGATTCTCATGCCTCAGCGTTCTGAGTAGCTGGGATTAGAGGCGTGTGCCA CTACACCCGGCTAATTTTTGTACTTTTTAAAGTAGAGACGGGGCTTTGCCATATTGGCCT GGCTGATCTCAAACTCCTGGTCTTGAACTCCTGGCCACAAGTGATCTGCCCGCCTTGGCC TCCCAAAGTGCTGGGATTACAGGCGTAAGCCACTACACCTGGCCCTCTTCATCGAATTTT ATTTGAGAAGTAGAGCTCTTGCCATTTTTTCCCTTGCTCCATTTTTCTCACTTTATGTCT CTCTGACCTATGGGCTACTTGGGAGAGCACTGGACTCCATTCATGCATGAGCATTTTCAG GATAAGCGACTTCTGTGAGGCTGAGAGAGGAAGAAAACACGGAGCCTTCCCTCCAGGTGC CCAGTGTAGGTCCAGCGTGTTTCCTGAGCCTCCTGTGAGTTTCCACTTGCTTTACATCCA TGCAACATGTCATTTTGAAACTGGATTGATTTGCATTTCCTGGAACTCTGCCACCTCATT TCACAAGCATTTATGGAGCAGTTAACATGTGACTGGTATTCATGAATATAATGATAAGCT TGATTCTAGTTCAGCTGCTGTCACAGTCTCATTTGTTCTTCCAACTGAAAGCCGTAAAAC CTTTGTTGCTTTAATTGAATGTCTGTGCTTATGAGAGGCAGTGGTTAAAACAGGGGCTGG CGAGTTGACAACTGTGGGTTCAAATCCCAGCTCTACCACTTACTAACTGCATGGGACTTT GGGTAAGACACCTGCTTACATTCTCTAAGCCTTGGTTTCCTGAACCTTAAAACAGGATAA CATAGTACCTGCTTCGTAGAGTTTTTGTGAGAATTAAAGGCAATAAAGCATATAATGACT TAGCCCAGCGGCCTGCAGGCAATACATGTTAATGAATGTTAGCTATTATTACTAAAGGAT GAGCAATTATTATTGGCATCATGATTTCTAAAGAAGAGCTTTGAGTTGGTATTTTTCTCT GTGTATAAGGGTAAGTCCGAACTTTCTCAGACTGGAGGTTACATTCACATCAGTCTGTCT TCCCCTGCGGATGGCCTCAGCCCTGGGTGGCCAGACTCTGTGCTCACAATCCAGAGCAAT GGATCC OMIM ID 173511