Entrez gene ID | | 282617 |
Official gene symbol | | IFNL3 |
Full name | | interleukin 28B (interferon, lambda 3) |
Aliases | | ,IL-28B,IL28B,IL28C, |
Gene summary | | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.13 |
Gene position | | 39735611 - 39734272 Map Viewer |
Gene orientation | | minus |
Gene size | | 1340 bp |
Gene sequence |
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OMIM ID | | 607402 |
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