Entrez gene ID | | 2829 |
Official gene symbol | | XCR1 |
Full name | | chemokine (C motif) receptor 1 |
Aliases | | ,CCXCR1,GPR5, |
Gene summary | | The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21.3-p21.1|3p21.3 |
Gene position | | 46068979 - 46062291 Map Viewer |
Gene orientation | | minus |
Gene size | | 6689 bp |
Gene sequence |
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OMIM ID | | 600552 |