Entrez gene ID | | 28513 |
Official gene symbol | | CDH19 |
Full name | | cadherin 19, type 2 |
Aliases | | ,CDH7,CDH7L2, |
Gene summary | | This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq] |
Location | | Chromosome: 18 Locus: 18q22-q23 |
Gene position | | 64271216 - 64171321 Map Viewer |
Gene orientation | | minus |
Gene size | | 99896 bp |
Gene sequence |
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OMIM ID | | 603016 |
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