Entrez gene ID | | 2852 |
Official gene symbol | | GPER1 |
Full name | | G protein-coupled estrogen receptor 1 |
Aliases | | ,CEPR,CMKRL2,DRY12,FEG-1,GPCR-Br,GPER,GPR30,LERGU,LERGU2,LyGPR, |
Gene summary | | This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7p22.3 |
Gene position | | 1126443 - 1133451 Map Viewer |
Gene orientation | | plus |
Gene size | | 7009 bp |
Gene sequence |
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OMIM ID | | 601805 |
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