Entrez gene ID | | 2880 |
Official gene symbol | | GPX5 |
Full name | | glutathione peroxidase 5 (epididymal androgen-related protein) |
Aliases | | ,-, |
Gene summary | | This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p22.1 |
Gene position | | 28493789 - 28502728 Map Viewer |
Gene orientation | | plus |
Gene size | | 8940 bp |
Gene sequence |
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