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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAPGEF1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2889
Official gene symbolRAPGEF1
Full nameRap guanine nucleotide exchange factor (GEF) 1
Aliases,C3G,DKFZp781P1719,GRF2,
Gene summaryThis gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.3
Gene position134612925 - 134452157  Map Viewer
Gene orientationminus
Gene size160769 bp
Gene sequence
OMIM ID600303