Entrez gene ID | | 2892 |
Official gene symbol | | GRIA3 |
Full name | | glutamate receptor, ionotrophic, AMPA 3 |
Aliases | | ,GLUR-C,GLUR-K3,GLUR3,GLURC,MRX94, |
Gene summary | | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq25-q26 |
Gene position | | 122318096 - 122624766 Map Viewer |
Gene orientation | | plus |
Gene size | | 306671 bp |
Gene sequence |
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OMIM ID | | 305915 |
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