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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL18 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 29074 Official gene symbol MRPL18 Full name mitochondrial ribosomal protein L18 Aliases ,HSPC071,L18mt,MRP-L18, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus. [provided by RefSeq] Location Chromosome: 6   Locus: 6q25.3 Gene position 160211492 - 160219461  Map Viewer Gene orientation plus Gene size 7970 bp Gene sequence >MRPL18:64380949..64388918:Length=7970 TGGCGTGGAGAGTTTGGGGATCTACAGCAGCCAAAGGCTTGTCCCTGACTTTATATGGCT GCTCCTGGCGAGCGACTGAGTCGTCCGTGAGGAAAAAGAGGCGAGGCTTTTCCGAGATCG TCTCAGCGATGGCGCTTCGGTCGCGGTTTTGGGGGTTGTTCTCGGTTTGCAGGAACCCTG GTAATTAGTCTTGCCCCCCTTCTCCCAGCTCACTCGCCTGGGCTTGCACAGTACATTGGA ACGTGCGGGTTCTATTTTGTATTCGACGTGCCGGATCGAAATAGAGCTCGCGGCACTGCG AAGACCACAGTAGGAAGTTAAGGACGGGGTCAGTGCTGACTCCACCCTGTGGGCATACGT ATTTTTCGTCCCCTCGGGCCTAAAGATTGGGGGTGTAAAAGCGGATAGACGTTAGAGCGG GTTCGTGCGCTGTCCATATCCGTCATTTTTAAGCCCTGTGCGGTTTTTCCCGTTGCCCAG GGTGCAGGTTCGCAGCCCTGTCAACCAGCTCCGAGCCGGCAGCGAAACCTGAAGTGGACC CTGTGGAAAATGAAGCTGTCGCCCCAGAATTCACCAACCGGAACCCCCGGAACCTGGAGC TTTTATCTGTAGCCAGGAAAGAGCGGGGCTGGCGGACGGTGTTTCCCTCCCGTGAGTTCT GGCACAGGTAATTAAATCTGCTTGTGATTGACAAGGGCAGTGCACCCTACAGACTATTTT CATTCATTCAACTCCAGGCACTCTCCCAGGTAGCTGCCATGCGGCGGGTAGAGGCAGGGT TCGCGGAGGGGCTGGAACAAACAACAAATAGGTGTGATGGGGGCTATTTAAAGAGGATGT TACAGTAGCGGACAGGATACCTGCCTGTCTGAGGTGACATTTAAGAAGGTGAGATCTGAA AGAGGAAGAAGCCTAGTCATCTGCCAGAAAGAGCAGTCCTAGCAAAGGAAACTGCTGGGG TGAGGAACTGAAGGGCTTGTGGATCTGAAGCTCAATGGGCAGAGGATGAATGGCCCAAGA TGAACATGGAGGGGTAAGGAGGCGACAGATGATTAGCTTTGTAAGTCAAGATGAGCACTT TAGACTTTCTTTTCATTATAGTGGGAAACTACGAGAGGATTTAAAGCTTGAGCCCGAATT GGTTTTTCAAGATCATTCTGGCTGGGCGCATTGTCTCATGCCTGTAATCCCAGCACTTTA GGGAGCCAGCCGAAGAAGCCGGATCATCTGAGGTCAGGAGTTTGAGACCAACCTGGCCAA CATGGTGAAACCCCGTCTCTACTAAAAATATAAAAATTAGAGGGGCGTGGTGGTGCACGC CTGTAATCCCAGCTACTCCAGTGGCTGAGGCACGAGAATCACTTGAACCCAGGAGGCGGA GGTTGCAGTGAGCTGAGCGCCTGGGCGACAGAGCAAAATTCTGTCTCAAAAAAAAAAAAA TCATTTTAGCTGCTTTTTGGAAGATTAAATTTTTGAGGGAGCAGGACTTGAAGAAAGACC AGTTAGGAGTCTAGTATGACTTGAGATACTTTGTTATAAAGGTGGTTGTTTAATGAACAC TTACATTTGCCAGGAATTATGCTACTTGCTTTATATGTTTTTTCTCATTTAATCCTTAAA ATTACATCATGAAGCAGTTATAATTTCCCCCATTTTACAGGATCAAAGAAATTGAGGTTT AGGGAGACATGATTAGTAAGTGCCAGAGCTAAGATTTACATATGTTTTAACTGACCTCAG AGCCAGGACGCTAGGTTATTACCACTATACTACAGCATGTAAGTGTTTATCAGGTTTATC TGCTGCTTATCTGCTTGGTGAGGATTTTTTAGAATTTCTTAAGGACTTCTTAAGTACTAT GTAAAGTTGTAAGAGTAAATTGGAAATCATTACTGTGTGATGTATTATTTATTTATTGAA CAAGCATCATACCTGTATCACTTGCTAGGCATTGCGTTAGAGGCAGGAGTTACAAAGATA AAGTAGATGTTATCCCTGTCATCAAAAGTCTTAAGTTTCATAGTGGAAAGTGGAATGGGG ATAATGATGTGTTACAGTTGCTGTAATACATTTTTACTCATAGAGGAGGGAGTCCAAGAA AGGGAGTAGGCAGTTCACTTTTTAAATAATCTGGATCTTAAGGCTAAAAATCTTTTGAAA CACCCAACCTATTACTTTCTTTTTTCTTTGTTTTTGAGACAGGGTCTGGGTCTGTTGCCC AGGCTAGAATGCAGTGGTATGATATCTGCTTACTGCATCCTTGACTTCCCTGGGCTCCAG CAATCTTCCCACCTCAGCCTCCTGAGTGGCTGGGACTAGAGGCGCATGCCATTACTCCCA GCTAATTTGTTTTGTTTTGTTTGAGACAAGCTCTGGCTCTATCACCCAGGCTGGAGTGCA GTGGTACAGTATCAGCTGGCTGCAACCTCTGCCTCCCAGGCTCAAACGATTCTCCCATCT CAGCTTCCTGAGCATCTGGGACTGCAGGCACACACTACCATGGCCGGCTAATTTTTTTCT TTTTCTTTTTTTTTTTTTCTGGTATTTTTTGTAGAGATGGGGTTTTGCTGCTGCCCAGGC TGGTCTCGAGCTCTTGAGCTCGAGAGATCTGCCTGATTCAGCCTCCCAAGGTGCTGGGAT TACAGACGTGAGCCACTGCACTCGGCCCCAACGCATTACTTTGATTTAATATTTGGATCA TTAAAAATAACTAAAGATGTATTTCCTCATTTTTTCTCTGTCTGCCTTACTCGCAATATT AAAAGTAGAGAATTTCAGAATATTATAGTAGGAAATGACCTTTGACATAATGAATCGGGC CCTTCATTGAACAAATGGTTCAAGTGTCAGCAAACTACGGCCCGTGGGCCAAAGGTAGAT TGTGAGCTAAAAACTTGTTTTTACTTTTTTTAAGTTAAAAAAAAAATCAAAAGAATATTT TGTGGCTTGGGAAAATTAAATGAAAATCAAATTTCGTTGCCCAGGTTCTTAGAACCTAGC TGTACCTACTCTCATTTGTTTACGCATCACCTGGCTGTTCTAGCACTACAATGGCTGAGT CGAACAGTTTCAACAGAAGCTATTGGACCTAGAAAGCCTAAAATATTTACTATCTGGCAC TTTGTGGAAAAAGATTGTTGACTCCTGGTTTAACAGATTGTGATTTTTGGCCGGGCGCGG TGGCTCACGTTTGTAATCCCAGCACTTTGGGAGGTCGAGGCGGGCGGATCACGAGGTCAG GAGATCAAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACACAAAA AAATTAGCCAGGCGTGGTGGCAGGCACCTGTAGTCCCAGCTACTAGGGAGGCTGAGACAG GAGAGTGGCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACT CCAGCCTGGGCAACAGACTGAGACTCCGTCTCAAAAAAAAAAAAAGAGATTGTGATTTTT TACTAGAGCCACCAGGAAAACCAGGAGTAGACTCCATATTTCCAAATCTAATGCCTCTTC TATTTCACATTGAGAATCCTAGTGAGAATCTAATGATTTGGGTGTGTTTTCTTTAACTTA AACTTGACTTTTTAAAGGGTAACATATACGTATGTTATAAAATCCAAAGGGAGTACAGTT TCTTGTGTGTCCTTCTAAAGATTGTCTATGCATATAAGCAAAAACTGTTAAAAACAATAA ATCTTAGCATACGATAAACACTTCCGCATCTTTCTTCACCACCACCCTCAACCACCCCAA GCACGCACTTAAAAATACATCTTGGAGATTCTTCATGGTAGTTAAGAGCATTGACTCTGG AGCCAGACACTGGGACTTAAACCATGGCTCCATTACTTACTAGTTTTAATCTTTTTCAAG TTACTTAACCTTTCTGTGTTAGTTTCTGCAGCTAAAAAAAAATATAGAAAAAATAATAGA ATTGAGACATAAGCTTTATCTATAAACCGTTAAGACAGGCCTGGCATATACTAAGTGCTC AGTAAATGTTAACTATTATCTTCATCATTATAAAGCATTATTTCATTCATTTCAGTAACT GTATGGAATACTATTGCATGGATTTTACTTAACTCGCTCCTAGAGGGTGATTATCTTTTA TGATTACAGTGTTGCATCGAATTGTCTTGTCCATGCATTTTGTTAGTGAGATTGAGCATA TTTTTGTGAATTTGAGTCATTAATATTTTTCTTTTCTGTGAACAGTCTGTTTGGATAATG CTTTGCCTATTAAGTTATGAAGGGGTGGGTTGCCCCTCCTCACCTGTGGGTGTTTCTTGT TAGGTGGAACGAGAGACTTGGAAAAGAAAAAGACACAAAGTATAGAGAAAGAAATAAGGG GACCCAGGGAACCAGCGTTCAGCATATGGAGGATCCCGCCAGCCTCTGAGTTCCCTTAGT ATTTATTGATCATTCGTGGGTGTTTCTCTGAGAGGGGGATGTGTCAGGGTCACAAGACAA TAGTGGGGAGAGGATTAGCAGACAAACATGTGAACAAAGGTCTTTGCATCATAGACAAAG TAAAGAATCAAGTGCTGTGCTTTTAGATATGCATACACATAAACATCTCAATGCTTTACA AAGCAGTATTGCTGCCCGCATGTCCCACCTCCAGCCCTAAGGCGGTTTTTCCCTAACTCA GTAGATGGAACGTACAATCGGGTTTTATACCGAGACAGTGCATTGCCCAGGGACAGGCAG GAGACAGATGCTTTCCTCTTGTCTCAAGTGCAAGAGGCATGCCTTCCTCTTATACTAATC CTCCTCAGCACAGACCCTTTACGGGTGTCAGGCTGGGGGACGGTCAGGTCTTTCCCTTCC CACGAGGCCATATTTCAGTCTATCACATGGGGAGAAACCTTGGACAATACCTGGCTTTCC TAGGCAGAGGTCCCTGCGGCCTTCCGCAGTGTTTGTGTCCCTGGGTACTTGAGATTAGGG AGTGGTGATGACTCTTAACGAGCATGCTGCCTTCAAGCATCTGTTTAACAAAGCACATCT TGCACAACCCTTAATCCATTTAACCCTGAGTTTGACACAGCACGTATTTCAGAGAGCAGG GGGTTGGGGGTAAGGTCATAGATTAACAGAATCTCAAGGCAGAAGAATTTTTCTTAGTAC AGAACAAAATGGAGTCTCCTATGTCTACTTCTTTCTACACAGACAGTAACAATCTGATCT CTTGCTTTTCCCCACAAGTTATTGATCATTTTCTTGTTAATTATAGGAGGCTTTTAACAT ATTGTGTAAATTAGCTCTTTGAACAATATATGAGTTTAAAATATTTTTTCTTTTTATATT TTTGTGACAGGGTTTCACTCTGTCACCCAGGCTGGAGTGCAGGGCATTATCACGGCTCAC TGCAGCCACAACCTCCTGGGCTCAAACAATCTTCCCACCTCAGCCTCCCAAGTAGCTGGG ACTACAGGTGCACACCATCACGCCTGGCTGATTTTTTCTATTTTTTGTAGAGACAGAGTG TCACTGTGTTGCCTGGGCTGGTCTTGAACTCCTTGGCTCTAGCAGTCCTCCTGCCTCAGC CTTCCAAAGTGCTGGGATTACAAGCTTGAGTCACATGCCCAGCCTAAAATATTTTTTGTT TCATTGCTTTTCTTTTGACTTCATTTTACTTTTTTTTTTTTTTTTTTTTTAACCATGCAG CAAATTTTGTCCATCATTTCTTTTTTATGCCATATGAGGGGCTGGGCATGGTGGCTCAGC CTGTAACCCCAGCACATTAGGAGGCTGAGGTGGGTAGACTGCTTGAGCTTAGGAGTTTGA GACGAGCCTGGGCAATATGGCAAACCCTGTCTCTACAAAAAAATACAAAAATTAGCTGGG TGCAGTGGCATGCGCCTGTAGTCCCAGCCACTTGGGAGGTTGAGGTGGAAGGATGACTTG ATCCCAGGAGGCAGAGGCTGCTGTGAGCCAAGTTCGTGCCTCTGTACTCTAGCCTGAGAG ACAGAGGCAGACCCTGTCTCAAAAAAAAAAAAAAATGGCCATATGAAGCTGGACACAGTG GCTCATGCCTGTAATCCCAGTGCTTTGGGAGGTTGAGAAGGGTGGGTCGCTTGAGGCCAG GAGTTTGACACCAGCCTTGGCAACATAGGGAGACCCTGTCTCTACAAAATAAAAATTATC TTGGTGCAGTGGCATGCACCTGTAATGCCAACTACTTGGGAGACTAAGGCAGGAGGGTTG CTTGAGCCTAGGGGTTTGAGGCTACAGTGAGCTGTGGTTGCACTGCTGTACTCCGAGCTG GGTGACAGTGAGACCCTGTTTCTGAAAAATAATAAAAGCCATATGACATGGTTTGATGTC ATATTTAAATATGCATACCTTGAGATTATAAAAAAATTTCTCATGTTTTCTTCTAGTACT GTTATGATTTCAGTTTTTGCATTTAAATTTTTGTTCCGTCTTATATTTATTTTGGTGCTA GCTATAAATAAAAGCAAAGAGTAAGTATATCCATGTCATGCATATGTTCAGTAACTTAGC TCTGTCTCTTCAAATCTCTTTTTGAAGTAGATCTGTAAATAAAACTCAGCTCTTCAGAAA CAAATTTCTTCATGATACTTGAACTATTTAGTTTGTTATTATTGAGGATATTCTCATAAA GGCGGAGGAAAAATACTTTTCCCAAGCAAAATCCAAGTTAAATATGTTGAAGTAAATGAA CCAAACACTGGATTGTTGAAAAATATTTAGTCATTTATTCACCTCAATTAATGTAACTTT AGGATACAGATTCTTCTGTGATTTTATTATCTTCTCACCCCATTTAGGTTGCGAGTTATA AGGACTCAGCATCATGTAGAAGCACTTGTGGAGCATCAGAATGGCAAGGTTGTGGTTTCG GCCTCCACTCGTGAGTGGGCTATTAAAAAGCACCTTTATAGTACCAGAAATGTGGTGGCT TGTGAGAGTATAGGACGAGTGCTGGCACAGAGATGCTTAGAGGCGGGAATCAACTTCATG GTCTACCAACCAACCCCGTGGGAGGCAGCCTCAGACTCGGTATTTTTGTTTTCATGTACT TATTGAAAAGGTATTGTGTTAATTCTTGGCATTAGATAACTTACATAATAATAACAGTTT TTACTTACCAAATACTTTCCATGTGTCAGACCCTTTGGTGAGTACTCAACAGTGTTACTT CATTTAATCCTCACATCAGTCCATAGGGTAGGGACTAGTACTCTCATTCTATACAGAAAT AAACTGAGGCTTACTTGCCCAGAGTCAGTGTATGGTGGATTTCAAACCCAGGGTGACTGA TTCTGTAGTCCATGATGTCAGCCACTGTATTTCCTGTTCATATATTGACATCTTGTCCAT ATAATATTTTGAAATGCTGCTGAACCTTGACATCTCTACATTTCCTTTTTACTTACATCA TTATTAAGATCACTTTCTGAAAAACCGTTGTAGGCTGGGAAGTTAGCAAGAACAAATCAA TTTATTTCTGTCTTTTGGAAGGTGAAAGTATTTTCAGCCTACTCGTGCTGCTGACTTAAT CTTTTCCTTTTTTTTCTGATTTTCAAAACCAGATGAAACGACTACAAAGTGCCATGACAG AAGGTGGTGTGGTTCTACGGGAACCTCAGAGAATCTATGAATAAATGGAAGCATTAATTG TTTTGAACATGTAAATATAAATCTGTCAGCCACTACAGCCATCAAAAGAGAGCATCTGGA AGAACAGCCAGCTTGGAAGTTTTACAGCAATAATGTTGCAGTGGAATATTATTTGTAGTT AAGGTCATCCTCCTCCCCTTTCTGTTTTTTTAAATCAAGAACTACGTTCTGCCCCTCTCT TGGGCTTCAGAAGCATCTAAGAAAAGCAGTCATCAATTATAATTAACTTTCAAAGGGCAA GTCAGAAGTTGTTTATAAATTACAAAATAAAGGCATATTATGAACTCTTA OMIM ID 611831