Entrez gene ID | | 29082 |
Official gene symbol | | CHMP4A |
Full name | | chromatin modifying protein 4A |
Aliases | | ,C14orf123,CHMP4,CHMP4B,FLJ61658,HSPC134,MGC142093,MGC142095,SNF7,SNF7-1,Shax2,VPS32A, |
Gene summary | | CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM] |
Location | | Chromosome: 14 Locus: 14q12 |
Gene position | | 24683185 - 24678787 Map Viewer |
Gene orientation | | minus |
Gene size | | 4399 bp |
Gene sequence |
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OMIM ID | | 610051 |
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