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Gene information for MRPL22 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29093
Official gene symbolMRPL22
Full namemitochondrial ribosomal protein L22
Aliases,DKFZp781F1071,HSPC158,L22mt,MRP-L22,MRP-L25,RPML25,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q33.1-q33.3
Gene position154320633 - 154348971  Map Viewer
Gene orientationplus
Gene size28339 bp
Gene sequence
OMIM ID611835