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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NXT1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID29107
Official gene symbolNXT1
Full nameNTF2-like export factor 1
Aliases,MTR2,P15,
Gene summaryThe protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p12-p11.2
Gene position23331373 - 23335408  Map Viewer
Gene orientationplus
Gene size4036 bp
Gene sequence
OMIM ID605811