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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GRP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2922 Official gene symbol GRP Full name gastrin-releasing peptide Aliases ,BN,GRP-10,preproGRP,proGRP, Gene summary This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] Location Chromosome: 18   Locus: 18q21.1-q21.32 Gene position 56887400 - 56898003  Map Viewer Gene orientation plus Gene size 10604 bp Gene sequence >GRP:4678264..4688867:Length=10604 CCAGCGGCTGCGGCGGCGGAGCTCCTCCGAGGTCCGGGTCACCAGTCTCTGCTCTTCCCA GCCTCTCCGGCGCGCTCCAAGGGCTTCCCGTCGGGACCATGCGCGGCCGTGAGCTCCCGC TGGTCCTGCTGGCGCTGGTCCTCTGCCTGGCGCCCCGGGGGCGAGCGGTCCCGCTGCCTG CGGGCGGAGGGACCGTGCTGACCAAGATGTACCCGCGCGGCAACCACTGGGCGGTGGGTG AGTGTCCTGGCCGCGGGAGCCGCGCGCTTGTCCTCCTCTGGATCAGCCAGCCGGAGGGGA CCTGTCTCCCCATTTCTTTGCGTTTCCCTGGCCCAGCTTTGGGAGCTGGGTTTGTTGTGA CCTTTCTATCGGCAAACACCTTCCCCGTTCTCCTAAAACTCCACCCCACCTTTCCCCATT CTAGGGAGCCCATGAGTCCCTAGTCAGCCGCAGGCTGGTCCGCTGATCCTTTCCCGCTCG CTTCCAGCCTGTCTTCCCCAGGGCACCCGAGCTCCCAACAGCCAACCCCGGTGCAGATCA CCTTCCCTCTGCGCCCATCCTACATCTCCTTTTGTCCGCCTAGTCTCAACCTGTCTGGCA CGGTACTCTCCTAGAATAATCTTGGGGAGCGTTGTCCCTTGAAAGCATCTCAGAACCCTG GTCCAGCTCGGTGGCCTCAACAGCGACTGGCATGGGCTGAAATCTAAGCTGCGCCTATGC TCCCCGCAAAGCCACAGGTGTGGGGACCTAGGGTGCAGCGCTCCCGCCCCGGGTTTCACA TCTGTTCAGTGCGCAGTGCCCTGAATCCCGCCTGTCTGTGACTCTCTGGAGTTTCCTCAG TCCTTCTCTTCGCTTTGCAGCGATATTCTTTTCCCTGCCCTTTTGCCCTCCCTCTTTCCA GCCAGCAGGCTCTGAGCTTGGGGAATCTCGCCTGCTCTCCAAGCTCATCCCGATCTCTCT GCCCCTCTGAGCTCCGCTCTTTCTCCGCCCTTCTTGACCCACGACTTCGCCCTTTCCCCT CGCTCCTTTCCCATTCCCTCTGCAACAGGTCCTGCTCTCTAGGCACCGGCTTGGAGGCTC CCTCGCCATGGCCCCTAGAACCCAGGCGGAGAGGACGGCCGCGCTGCGGGTGCGGAGGGC GCCTGCGGGTGGGGTCAGGATTCCGCCCTGCGCGCACTCGCTGCTTTCGCTCAGCTGGGA GGCAGGAAGCGCCTGGCAGCCTCGGCTCACCCAGCATCACCCCAGGGCTCTCGGCGTCGC CGAGCATAGCTTCCAGCAAACGCAGAGCGTCCAACTTCCTCACTCCCCCACCTACCCGCC CCACAAAAGCCAACTACAACAACCCCAACCAGCTTCTTGGGAAGCTGGTTAATCCCTGAA GAGATTTAAGAGTGTGTATGTGTGTGTGTCTCTGTGTGTGTGTGTCTCTGTGTGTGTGTG TGTGTGTGTATTTCCTTAGCCATCTACTTAGAACGGGCGCTGGGGAACGGTGTGTTGAAC AAGTACTTGCTAATTCATATATCGGCTGATTCACAAATCTTGATAGAAGATAAATAATTT GGGGGAAGGAGTGGGACTGGAACTGTTGCTTCCTCAGCTCGTCTGTGTCGTGTGTGCTTT TGTGAGGGAAGTCGAGATCTTTGGGCTGCAATAGAGTGGTTTCCACTGTTGCTAAAATAA TCATTTGCCAAGTCTTGACAGTTCCAGAGATGAGAGGATGTGTGATCGCTGAGGGACAGG AGGAACCCAGCAGTCTGGTGTGGAGAGGAGAGGTTGGAATGGGTGAAGCTGAAAAACCCT CCATTTCAAGAATGAAGGATGCTTAGCAGGTGTTGAAGAATCCAAACTTAGAATTGATGC TTCTTAAAGAGGGCTTCTGGGAGCTTAGATCAAGTGGCCATTATCTGGCCCAGCCACCAG CCAATGGGGCTGGAAAGATGGAATGAAAGTTCTGGATTCCCAATCTCTTTGTACTCATCT ATATTATTGCACTAATAAAGCTTATTATTAGGTAACGCTTGCAGGCCCAAAGGAGGACAA TAGAGTTAACTGGGGAGTGGCATCGTGTTATTTCTGGTGCAAGTCAAGCCAATCTTGATT TGCTGTAGTTCCGCAGAACATCTGTCTCCAGGTATTTAGGGTGTCTGCCGTTTAATTGCC CTTCATAGTGGTACTTGAGCATTCCTAACCCAAAAGAATACCAACCAGTGGTGACCCCAA ATACCATTTTCATATTTATTCTCAAATGCACTTTTTTCTCTCCCTTTGATAACTGTGCAG AGTTGAGGAGGAGCAAGGGAAAGAGGGAGGTGAAGTAGAAACTCACATTTTAGCCTAAAA TTACCTTGCGGTTGAGAAAACGTTTGCTTTGAGTAACATGCCCTCTGTTGGAATATGAGC ATTGACAAGGATGAATGATGTTACACTTCAAATTTAGCTTTCAGTTATCTCAAGAAAATG CTTATCCTCTTCAATCACCAAAGACATGTAGTTTAGTTTTAATTATATAAAACCAAAGCT ACATGCTGCTGTCCATGAGGATGCTGTCAGCACACATTTACAGGCTTGGTAAGTAAATTG CTTCTTCTAGCTGAGAGAAGCATGGTGCAGCAATGGAAAAAAGGTTAACAGCTTGAAAAC TTAACAAATTTTTATCTGGCTTGATGTTCGTGGAAATGTTTTGTTTGTGTGATGAAAATA TATGACAACACTTATACTGGCTACTATTCCCTGTGCACCCATGAAATGCTCCTAACTGTG GTTCTAACTTGGACGTGAGACATATCCCAGAAGGTTGAATTTGGAAATACCAGTATTCCA CTGCAGAATGGCTTGTTATGGCCCCAGAAACTGTGGAATAGAATTTAAGTGTGGGTCCAA AAATACTACTTCTTAGTAGTACTCAACACTTTCATCTATGTCTTATTCATTTCTGTTTCA AACCTTCCCTTTAGTAGTATCTTTAAATGATTAATAAAAAGAACAAAAGCTCTTTTTTTC TCTGATCAAGGTTTTATTTTTTCAAGTGCCTGTCTTTTGTCTATGGTGAGGTTTCCATTA TTATGATATGGGCACTTGACAGATGATGTTGGGAGAAGAGGTGGAAGTGGGCGTATCATC CATGTTGCCATGGAGATGACGATTTGGTTGACAGTCACTAGCTCAAAAGCAAAACTGGAC CCAGGGAATGTGTACTTCCCTGGGATGTTACAGATAGCGTGCTCTCCTTAGCAACCAGTC TATGGAACTAGAGATAAAGAACTGATCCCCACACATTCCCCATATATGCAAGTACTGAAA GTTAGTACAATCACAGAATGGAGAATAACTTTCTCCTCCCATTTTAGAAAAGTCCACAAA ATTATTCAGGCATGACAAAAATGAGGTTCTTATGTGTGATATCTGCATCACTTCTCTGTT TTACTGGCAATAACTCTTTCTCATTTCCAGCATTCTAACTAGATGATAGTCAGTTAGAAG GGCAAGGTGATCTAGGTCATCACTGGGAGTATCAGGATTCTAATCCTGCCTTCCAACCAT CATGATTTAATTTCCTCCATATAAATAAAGTCAAATGCATCACTACTTCCTGGGAAGTTG CACAACATAATCACCGTTATGGCTGAATGCAAGGTTATTGAGTGGCTATCTGAGCACCAT GTGACCAAGCTGATACGTGAGGAGCCAGTCATTCAGGATTCCAGGTCTTCACTTGGGACA GTATCCCCAGTTAGGATCCTGAAATTGTGTGAAGTCTCATGTCATAAGCAATTTGGCAAA TGCTCACACTGCAATGCAGTAAACCTGATTTTAATGCTCCTTAATACTCATAGAATTAAT TTTTCTCAATTACATAATGCATCATGATATATTGGCATATAATCCCTATTTTTATAACAT TAGAAAGCCTTTTGTAGACCTTATCCTTATTTCCAGATCCCAGAATGATTTTAGCTACCT TATATTCTTAGCAAGTTAGAAGACATTGCCAAGCAGTGTAATAATGTAGTCTAGATTGTG AACTGATTTTAATCCTAAAATAGTTGCTTACATCTATGTGACCTCTGGCAAGTCTCATTT TCACCAAACCAATTAGCATATGGATCAAATGAAATCCAGCACATTTAAACATCCCATAAA CTGCAAATCGCAATACACATAAAAGCAATAAAGTTAAAGTGAGGGCTTCTCTGTTGGTGG ATAGAACTTCTGGGAAGGGGCCTCTTTCCATTTTAAGACTGAAGATCTTTCAAATTTTAT GTTTGCCTTAAATACTTCTAATGCCAGTCAGTGTTGGAACCACAAAGACCTTTTTCCTTG CACACTTTAGATCAAAAGCACCATAGTTTTGTTGACGTTAGAAATTTCAAAGTGCTACAA AGTCCAACTACAGAGAGAGGAAAAATCAACTGTAAGAAATAGAGAACATGAGAATATTCA AGCAAGGGTCTAAAGTGTTAAGAATGCAGACCTTGAATTCTGTACCCACTTCTGACTCCA AGTTATCCTCTCTTGCATACATAAATTTTCATGTTTTTGATGGTTTGGCCTCCTTAACAG CAGCTTTTTAAAAAAATTATTTACAAGGCTAGTACACATTCCTGGAGCCACTGATAGACT TTCAGACACCCAAGAGAAAATTCTGCATTTATGCGGCTGTAAAGTGTTACTCAGGGCTTG TTTTCAACTTGTTTTTCACTACACTCTTAACAAACAGTAAATCTGGGTAGTTTTCTCAGT TCAGTCTCAACTAAAACTCTGAGAAAGTTTAAATGAAAAATTCCTTTGGTATTTTTTTTA TTACGATAAAAGGAAAGAAATATTTTTAAAAAACCACACAAAGAAAAGCATGGAGACTTT TATTTTCAGCAGCAATTCAAAATTGGCTGGGGAAGATGTTTAAACTCCATCTTTCAGCTG GAAATAGAATTTGGTGCACACAGAATTGATGATAGAATTTTAGATATGGAAGCCTCCTTA GATTTAATCTAGTCTACCCTGTTCATTTTATAGTTGAGAAAATTGAAGACTAGGGGTGCT AAACGACTTGGCAGAGGTGACCTAACTAGTTAGGAGAGGTGCTGGAACCAAACCCAGGGT TCCTGGGTTGCAGTTCTGAATGCTGTCTAGCTCATTGCACATTTTGAACAGAGAGCAAAA TCTATCTGTCGTTTATGAACTAACTCTTAATAAAACATGATTTATTCTGCATTTAGGAGG AAGCAGCACAAACACAATTAGCTTTAAATTTCTTTTAAATTTCTCATTCATTCCCTTTGG TTAAATTTGTGGCATTCTGAGTGTTTTTGTTTTTGTTTTTACAGGGCACTTAATGGGGAA AAAGAGCACAGGGGAGTCTTCTTCTGTTTCTGAGAGAGGGAGCCTGAAGCAGCAGCTGAG AGAGTACATCAGGTGGGAAGAAGCTGCAAGGAATTTGCTGGGTCTCATAGAAGCAAAGGA GAACAGAAACCACCAGCCACCTCAACCCAAGGCCCTGGGCAATCAGCAGCCTTCGTGGGA TTCAGAGGATAGCAGCAACTTCAAAGATGTAGGTTCAAAAGGCAAAGGTAAAAGAAACAT ACATGCAAGATGGGGTGGGAGGTATCTGGGGAGAGGTGGAAAGAGGGCAAGTTCAAAGGA GGAAGAATAGAATTGCTTATGATATAAACCTTCACAGTCACTACATTAGGCTAACACATG CTAAGCACATTGACAGACAATTTCTACATTCTCTTCTTTTTGACATATAGTCAAAAGGAT ATTGATTCCAAACTCCAATTTAGGAGTTTTTTTCAGCAATTTTGTCTATTTGCCATTACG CATTGATGGGATTTTTTTTTTAACACACAGGCCCTACAAGAATGTTTTGATAGTGAGTCT GCAAACTATTTGAGTAAATCCTTGTGGATCTACAGATTTTATTTTATTTCTGGTGAACAC TAGTGGAAGTTCCTGTTTTTAGAAGACAGCATTCTTGTTTGCTACCTTTGACACAAAGTA GCACTTCTTCATATTTGTTCCAGGAGTACCTAGTTCAGGTTTCATCCTAATATTTTAAAA CTCAGTGAACATGTCTGAGATCAACAAATCCATCCTGTATATGATTTTATAGAGGATAGG GGAAAATAATTATACTAAACTGGCAATGCTTAAAGACAGTGAGCAAGATAAGAGAGAATA AAATTTACAGGAAGAAAGCAAGGCAACTGAAAATGAGGTGATTATCACTAACTTTTAAGT TTCCATGAAATGTATAATAAAATACAAAATAATAATTACAATAACAACGGTGGCTAGTTT TACTGAATATTTACGATAATCCAAGTATTGGGCTAAGCAGTTTACCTCCATTTTCTCGGC TTATGCTCACAGAAGTCTTAGACGGAAGATTCTATTATTCTCTCCATTTTAGAGGTAAGG AAACTAGTCCCATAGCTTTTCACTGATAAAATCAGGGTAAGGGCCTGTGTTCAGTCGGCC TCAGACAGTCTGTACCATGCCAGACATCTTCCAGAAATGGTCCTCATTGATCTTAATATA AAGGATCCAGGCTGAAGGCCTTGCTACTTGCTGCTTCTGACAATAAATAATATTGCTTTC CACTCACAGTACTGGAGAGCTTCCTTCTTCACTCTTTCATGGTGAAGACTGATGGCCCCT TTAGGGGCTCAGAGCTGCCTTTGCCAAGCCTCGGCTGGCTTTCTGGAGGGAAGCTTTCTA TTTCACTGCCCTTTGGGTCTATTCTGGTCTTTCTCTTTCTTTTTTTTTCTTTTTTCTTTC TTCCTTCCTTTCTTACAAGTTCTGGCTATGTGGTTTCTTTTCTTCCTTTCTTTCTTTCTT TCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTCCTTTCTTTCTT TTCTTTCCTTTCTCTCTTGCTCTCTCTCTCTCTTTTTTTTTTTGACAAGGACTGGCTATG TTGCCCATGCTTGTCTCAAACTCCTGGGCTCAAGTGATTTCCCTCAGCCTTGGCCTCCCA AATGTGGGTTTCTATGCTAAATGGAAACTGAAGTTCACTTGTTGCACTAAGCACCTAGAG GGAAAGTCTTTGTAGCTTTTATTCAGAAAAAAAACAAAAACCAAAAACAATCCTAGATTA AATAAACCAATACAGAAATAAATACCAACTTTGTACAAAACCCCAAGCGATTGTCTGGTC CATACCTGTGTCATAGGTGTTATGTCATCAGCCCCCTTCTTTACTGATTGATCCCATACT CTGAGGGTTCTGTGAACTTGCAGGTGACTTCTCAGATTCTAGCTGCCATGCCTTTTTCAT GGTCAGGTGCTTTGCCAGAGTTCCTGTAGGTGGATATCCAACAGCAGTACCCTTCTCATT TGTCTGAACAGTAATAAAAATTGCCACCACAAAACCCTTGAAAATAATTTTTGCAAACAT TGAACTGGACTTGCCCTCATAGCTCGTTCATGAAATACTCCCCTCTACTAACACACAATC ATGTTACTATTCTATAGTGCCTCATTTTTGAAACAAACAGCAGTGTCCAGTTTGTTATTT TATTTCCTCAACCTGGCTCTGCATATCTTTGGAATCTTTTGGCAAATTCAACTCCTTCCT TAAGGATCAAAAATTTTCCACCACATTCAGAAGAATATTCTGTAAGCTTCAAAGGCAACA GCAAAAAGAATAGCTCCACAAAGGTGTCTGAGTAGCAGTATAATAGGATGGGTTGAGTGG GCAGCTGCCGAGAGTGACTGCTTAAAGGGGGCAGTCCTTATCCCAAGTGAACTGAAAAAG GTCATCAAAAAGATGATAAAAAAAATCAGGCTTTGCTTTTCTATTATTTTTATGCATTGT TTTTCTTTTTACAGGTTTAGAAAGCCCATCTCATTTAATTCCACCTCCAGTTGAATAATT AGTTATCGCACACATTGGTACTATTCTTTTGGCTATATTTCCTAGTAACACAAAAACAAG TTCCACAGTTAGTGTTTGCAGAGACCAAAATATTTTATTGCTTCTCTTGCACTGGAAATT CCACCTCAATGAAAGTATGCTGTTATGAAAATTGAAAACACCTTACAATGATCTTATTCA AAAAGAAGGGGTGCCAAGAGAGTAGTTCTATTAGAACCCATATATCTCCCATATCTTAGA GTTATGGGAGTGTTAGAGGGAAACTTAATAACTTAGCTAAGCATTGCCAGAATTAGCAGC AGGAGTTTTCAGAGGCTGAAGGACTGTTCTTAAAATTAAAAACTATCTACATATGCTCTC CTCTCTCATTTTAGTAATAAAACATCAAGTACTGTTGCCAACTCTCTTGGAGCTGTGGTT AGAAACTCCAAGCATTTCCTATGTTTTGATGACAAAGATATTTACTTAATTCATAAAGGA TGTGTGTAATGTGCACTGAAACTAGATTGCTCGACCATGGAAACAGCTCCAGAACTTTCA GAGCAATTATGCCCAGCAATGTTCAAGGTTAACCTTAATCCTTTTAACTGTGCCCTTCTC ACAAATCTTTTAATTCTATTCTGCAATTAATGGAACTTTTCCCCCATGGTTTCTGCAACA TGAAACTCTGTTCTGTTTCTGCAACATGAAACTCATCCCCATGGATGAAGCTCCAGGGCC TCATCCATGATCCTGGATGTGGTTGTTCACTGTCCTGGGTTTCAATGGAGGTTTTAGTTG GCCTTTGGTCTACCTTTATAATTTGGACTTAGTCCCTTATTCTTTGCAGCTTAGGTCTCT CCTTTTATTTAGTGGACATGAAGAGGGCAAGGAAGTGAGCTACAAAGGCTGTTATGGAAA GAAAGTAAATGTGTTCGTTCTTCACTTTTAAGGGACTGCTCTCACTGTCTCATCAAATCA GTACAGAGAATAGGAAGGTCTTTTTTCTGAATATTTGAAATGCTCCAAAGGAAGTGCCAA ATATAGAAAAAGCAACATAAAATCAAGAATCACTCATAACCTTCTGATTACCCTGGCACT TTCTATGAAGGAGTAGAGTAAAGTTGGCCCCCACCTGGAATATAGCTCCTCCCTACCCCC AACAATGGACCCTGCCCATTGCCTCCCAGTTCCTTGATCTTCCTAGGTTCCACAACTCTC TTTTTCCTTTTAGTTTTATTCCCTCCAGCCAAACCTCTCTTATTCAATATTTTGAGCCAA TGGGGGAGTTATGTAGATTTTTTTCCCTACACATTAGCTGGCCCCTTTTATGACCAATGA CTCATAAGGCAAGATGTGTGGTGGCATCTTCGGACAGGCAGCAGGCTTTAATAGGGCAGC CTGGGTTGGTGGAGGCAAGCAAAGCTAATTGGCATGCGTGGGAATCAAACCCCAGGCCCT GGGCTCATTAGCCCATGGTCAAAACAACTGAGCCAGAGGAGGTAATAATTTGCCCAAGAA TATCAGTAGTTCCTTTATTAGAAGAAAATGGCTGATATGGAAGTTGGGGAATCTGAATTG CCAGAGAATCTTGGGAAGAGTAATAAGCTCTTAGTCTCAACAAAAAGTGTTTTTTCATCT CAGCGCGTAAAGGGTGCTATATGGGAACAAAGAAGTATTTTAAAATTATAACTACTCATT CTTTCTTTAGCCTTAGTTAATTTGAGCAGAAGCCACAACAAGCAAACCACAATAAATTTA GAATTGGCAGAAATCCACATTAACTCCTCTTCCCAAGTTTCCACACTACTACCATTTACA GTTGTAGGTTTGTAATGTATAATTATGTAATGCAGAAACTAGCTTTGACTTGTGTAACGA TGCACTGTCAAAGTAAGCAAAGTAAGAATTGAAATTCCACATTCCCAGAATTTAACACTC AGCTGCTCCTCTAGTAATAAGTTCCTGGGGATAATACATTAACCAACATTGGTTGAAACA TACCTGAGTAATCATATCAGGATGCATGTTAAGCTGATAAAACAATAAGATCCCAAAATG CAGTAGCTCAAAAAAAAGTAGAAGTTAATTTATCTCCTGGGGGACAGCTCTGGTTCTCAA ATTTTACAGGCTCAGAATCACCTGCAGGGCTTGTGAAAGTACAGATTGCTGCGCTCCGCC CCCAGAGTTTCTGATTTAGTAGGTGTTAGGCTGAACCAAGAATTTGCCTTTCTAACAAGC TCCCAAGTGATGCTGATGACTTGTAGGAATGGATTTACTTCTAGGATTAGACTTCAGCTC ACTCTGTTTGCTGAACTCTTTCTAATATTTCTTAAGTTGGTAGACTCTCTGCTCCAGGTT CTCAACGTGAAGGAAGGAACCCCCAGCTGAACCAGCAATGATAATGATGGCCTCTCTCAA AAGAGAAAAACAAAACCCCTAAGAGACTGCGTTCTGCAAGCATCAGTTCTACGGATCATC AACAAGATTTCCTTGTGCAAAATATTTGACTATTCTGTATCTTTCATCCTTGACTAAATT CGTGATTTTCAAGCAGCATCTTCTGGTTTAAACTTGTTTGCTGTGAACAATTGTCGAAAA GAGTCTTCCAATTAATGCTTTTTTATATCTAGGCTACCTGTTGGTTAGATTCAAGGCCCC GAGCTGTTACCATTCACAATAAAAGCTTAAACACATTGTCCAAA OMIM ID 137260