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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Gpx2 (Rattus norvegicus) (Information is obtained from NCBI Gene database)

Entrez gene ID 29326 Official gene symbol Gpx2 Full name glutathione peroxidase 2 Aliases GPX-GI,GSHPx-2,GSHPx-GI Gene summary This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Knockout studies in mice indicate that mRNA expression and activity of this enzyme are induced by luminal microflora, suggesting a role for this peroxidase in preventing inflammation in the GI tract. [provided by RefSeq] Location Chromosome: 6   Locus: 6q24 Gene position 99372417 - 99376229  Map Viewer Gene orientation minus Gene size 3813 bp Gene sequence >Gpx2:complement(719661..723473):Length=3813 GGGAATGCTCAAAGGCCCTTTGTGAAATTCTTTCTGTCCTTCCTGGCTCCTCCTTCCTCC CCACCCAGTCAAGGAACTTAAGGAGGCTCCCACAGCCGGGCAGGACTCACAGCACTCCAG CATGGCTTACATCGCCAAGTCTTTTTACGATCTCAGTGCCATCGGCCTGGATGGGGAGAA GATAGACTTCAACACGTTCCGAGGCAGGGCCGTGCTGATTGAGAATGTGGCCTCGCTCTG AGGAACAACTACCCGGGACTACACCCAGCTCAATGAGTTGCAGTGCCGCTTTCCCAGGCG CCTAGTGGTTCTCGGCTTCCCTTGCAACCAGTTCGGACATCAGGTGAGGCGTCCCTTGGG TCCTACCCAAGGAGCCGATTGGCGGAGCCTGAGTGGGATAAAGAAAGGATTGAGTGTGTC TTGGAGTATCTGGACTTGAAGGGCACGCTTCATCAATCTAGGTCTAGGTGAACGTAAAAC AGCACAGGGAAGTAGAGATGGTCTGAGATTAAATATCAAGGGTGTGACTTTTATTACTGT CTTTCCAGAACAGTTCATGAGGGTTGCTACCAGGTCTCTCCATTGTGTCTTGGAGTACTT CATTATTTGTTGAATGAATGAGTGGAGACAATAGAAGGTTAAGAATCACTAAATTGGCAT GGTTGAGTGTCCTTGCAATCCTAGGAAGACGTGTGAGGTGGAGGCTGGGGATTGATGTGA GTTTGACTGACAGCGAACCTGGGCTTATCAGCAAGATCTCAAACATCAGCCCGTGAATAT AGCTCAGTTGCTAGATTCCTTGCCTAGCCTACACAAAACGTGGGTTTGATCCCAAGCACT GCAGAAGGCAGCGCTGATCGCTAGCCTGTAATCCCAGCATTTGGGAGATGGAGACAGAAA GATCAGAAATTCAAGGCGATCCCTTGACTACAGCAAGTTTGAAGCCAGCCTGGCCTGAGC AATTTGTCTCAGAAAAACAAACAATTGGAATTAAGCTGACCGGTTCCTTGGGCGTCCTTA GTCCCTGTTGCCTTGGTTCTATGCTTTGATGGCTCTGAGACCATTGTTTTCTGTTTGAAT TTCCCCGTGTGTTGATTTAATAGAAGTTGACTTAGCTCATAAGTTTATTGTGAGGCTTAT GGAATAAGACATATGAAAAATAAGGAGGGGTTGGGGATTTAGCTCAGTGGTAGAGCGCTT GCCTAGGAAGCGCAAGGCCCTGGGTTCAGTCCTCAGCTCCGAAAAAAAAAAAAGAAAAAA GAAAAAGAAGGAGAAAGATGTGGAAATAGTGTGCGAATATAAACAGTTTTATTATTTAAA GACTTGTTTCTAATCGGCAAGTTGGAAAGGGAACATGAGAGAAGGGAAAGGTCAGCAGCG TGCACACCTCCTCTGGACATCACATGCTCCTCAGTCTCTGAAGAACGGGTCACATTATTA CAGAGCTTCAGCGTGTACGCCTCCAGCTATCTTTTAGGGATTCTGGTTCTACTTAGGCTT TAACTGCACAAGCAAGCCAGGTGTCCCTAAGTGGACTCTCTAATTAGAGTCCCCACAGTT CAAATCACAGTGGCAGGAAGGATGGCTGAGATATACACAGGAAAGATGGCTGTGATATAC ACAGGAAGGGTGACTGTGGCATACACAGGAAGGGTGGCTGTGATAAACCAGAGATCCAGC CATCACTGTGCTCACAGATCCCTTCCCCTCAAGCCTCATTTTAGACTTTTCCAGGGAGAG ATAGGAAAGCCTAAACCTCATTGCAGCCGTTTCTCAACCCAGGAGGCACCTCTGGCCTTA CACCTCACTTGCGGCTGGCTAACTGCTGGAAGACGTCAAAACTCAGTATCCACAGAGCCA GAAAGGAGCACAGTCAGAGCAGAGGAAAGGAAAAATGGGAGGGANNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGAGATGAGTAAATCTGCAGCCGT TCCCCCAGTCTGCATAATAATTCTGGATAATAAAAATAGGAGGGCTGGAGAGGTGGCTCA GCAGGTAAGAACACTGACTGTTCTTCCAGAGGTCCTGAGTTCAATTCCCAGCAACCACAT GGTGGCTCACAACCATCTGTAATGGGATCCGACGCCCTCTTTTGGTGTGTTTAAAGACAG CTACAGTGTACTCATATCCAAAATAAATAAATAAATCTAAAAAAAAAAAAAAAGAAAAGA AAAAGACAAAAAGTTGCTTTCAGAATGGGTCACAGAAGTAGCTGAGTAATGTAAGTTTAA ATTATTTTTTAACAAAATAAGAACTAAGTATATTTAATATAATTTTAAAACATTTTTAAA AAATAACGTATTTTGTGTGTGTGCTATGGATGGGAGTATGTAAGGGCAGTGCCTGTAGAA AGGCCAAAAGAGGGCACTGGATAATATAAAATATAAACATAAATTTAATATAAAATTTCA ATGAGGGAGGGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGCGGTGTGTACATAGAGTACATAGATGTAGAAGCACCTCCTTTCCCTC TCTTCCCTGGCCTCAAGGTTCCTTAAAGCACCAAACACCAGATTAGGGTCTGAAGCAAGT GTTAAAAACTGCTGAATCTCTAATTATGTGTATTAATTTATTTTAATGTGCGTGAGGCTG TGCACCTGCCACAGTGCACAGGTAGAGATTCGAGGACAATTTATGAGAGTAGACTCTTTT AAATCATATGGTACTCCCTGGCCTCCAGAGTTTTGGATGTAGCCTATCATGCCGCCACCA AAGGCCACTCAACCCCGATGACCTGAATTCAGTCCTCAGAACCCATGTGATGGAAGGAAA GAAGTGATTTCCACAGGTTGTTCTCTGACTTCTACATGTACAATGGTGACACTCAGTATA AAATAAATGTAAAAATAAGAAAACAACAACAACACAATGGCAGGGGAGGGCAGAGTAAAT GGAGAAGAGACACACATGAGCAACACACTCATACACACACAAAGGAAAGCGTGATCGTGG GAGAGAGTGTTGGAGAAGGAATGGTTTGCACTGGTGCATCCTTGGTTTCCTCTTCCTTTC TCCATGCTCTTTGTCTTCTCATCCAGGAGAACTGTCAGAATGAGGAGATCCTGAACAGCC TCAAGTATGTCCGCCCTGGGGGTGGGTTCCAGCCCACCTTCAGTCTTACCCAAAAGTGTG ATGTCAATGGGCAGAATCAGCATCCTGTCTTTGCCTACCTGAAAGACAAGCTGCCCTACC CTTATGACGACCCATTCTCCCTCATGACCGATCCCAAGCTCATCATATGGAGTCCGGTGC GCCGCTCAGATGTGTCCTGGAACTTTGAGAAGTTCCTCATAGGGCCAGAAGGGGAGCCTT TCCGTCGCTACAGCCGCACCTTCCAGACCATCAACATCGAGCCTGACATCAAACGTCTCC TCAAAGTTGCCATCTAAATGAGGGCTGCTCAGCCTAGGAATCTCCGACTGTTTCTCCAAG TAGTCCTCTTCAGAGCTCAGTGTACCCTCAGGAGACACTGGGAAACCGAAGCATTTCCTC AATATTGTCCCCTTGCCTTCCTGCCACCCATTTCCTTTAGCTCCCTAAAGGCTCTTGGGG AGTCCACTGGGGGCTCTAAGTCTGGGGTAGGTGCTAGGCCTTCTTCACAGAATGATGGCA TCTTCCTAAACCCTTCTGGGGGATGTCTGAGACGTTGTGAAGGGCCCAGAGCCAGCTCGG TTTAGAGTCCAATAAAGGGTAGGAATGACCTGG