Entrez gene ID | | 2950 |
Official gene symbol | | GSTP1 |
Full name | | glutathione S-transferase pi 1 |
Aliases | | ,DFN7,FAEES3,GST3,GSTP,PI, |
Gene summary | | Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13 |
Gene position | | 67351066 - 67354124 Map Viewer |
Gene orientation | | plus |
Gene size | | 3059 bp |
Gene sequence |
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OMIM ID | | 134660 |
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