| Entrez gene ID | | 29627 |
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| Official gene symbol | | Gria2 |
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| Full name | | glutamate receptor, ionotropic, AMPA 2 |
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| Aliases | | GluA2,GluR-K2,GluR2,gluR-B |
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| Gene summary | | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 2 Locus: 2q33 |
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| Gene position | | 172265154 - 172385284 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 120131 bp |
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| Gene sequence |
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