Entrez gene ID | | 2971 |
Official gene symbol | | GTF3A |
Full name | | general transcription factor IIIA |
Aliases | | ,AP2,TFIIIA, |
Gene summary | | The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq] |
Location | | Chromosome: 13 Locus: 13q12.3-q13.1 |
Gene position | | 27998681 - 28009846 Map Viewer |
Gene orientation | | plus |
Gene size | | 11166 bp |
Gene sequence |
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OMIM ID | | 600860 |
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