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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRPM5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 29850 Official gene symbol TRPM5 Full name transient receptor potential cation channel, subfamily M, member 5 Aliases ,LTRPC5,MTR1, Gene summary This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.5 Gene position 2444275 - 2425745  Map Viewer Gene orientation minus Gene size 18531 bp Gene sequence >TRPM5:complement(2365745..2384275):Length=18531 GAGGCCACCATGCAGGATGTCCAAGGCCCCCGTCCCGGAAGCCCCGGGGATGCTGAAGAC CGGCGGGAGCTGGGCTTGCACAGGGGCGAGGTCAACTTTGGAGGGTCTGGGAAGAAGCGA GGCAAGGTAAGGGCAGGCCCCAGGCCTCAGGTGATGTCCGCCTTGACCTGGAACCCATGA GGCCCCATTTCCTTCCCTGGAAGCTGAGTGCCAGGGTCCTCCTCACCCCTGGGGTCTGCT CCCCTGGGGCCATATTCAGAGCCCCCAGACAGGCAGAGTTCCAGAGCTGGAAGGAGTGGC TCTGGCCGGCCTCCTACCTCCCTGCAATAACCGGGACCCCTGAAGTCCCCCCGAGAGATT TGGAGGTGCAAGGTCAAGTGCATCCAGGGCCCCACCTCTGTCCAGCGCCCTCGGCTCACT GAGGGGGATGCCAGCCCAGAGAGGGGTCAGGACTGCCCAGGTCACACAGCAGGTCAAGGG AGGACTGGCCCTGTCCCAGAAGGGATATTGGGGGCCACTCTCCTCCTGCTACCTGCCCCC AATGCCCAGCACCTCCCCGGTACCCCCTGTGTCCAGCCCCCTTGATGCCCAGCACCTCCC AGTGCCCAGTGTCCCCCCATGCTCAGCACCTCCCCAGTGCCCCCTTGTGTCCAGCCCCCC CCAATGCCCAGCAGCTCCCATGCCCCGTGCCCCGAAAGCCCTGAGCTGCAGACCTGCCTT GCAGTTTGTACGGGTGCCGAGCGGAGTGGCCCCGTCTGTGCTCTTTGACCTGCTGCTTGC TGAGTGGCACCTGCCGGCCCCCAACCTGGTGGTGTCCCTGGTGGGTGAGGAGCAGCCTTT CGCCATGAAGTCCTGGCTGCGGGATGTGCTGCGCAAGGGGCTGGTGAAGGCGGCTCAGAG CACAGGTGAGGCCCCACCCGGCACAGGCAGCGCTCCCACCCCACAGGGCAGCCCGACCCC CTGACTGTCCCCGCAACCCGGCACAGGCAGTGCTCCCACCCCACAGGGCAGCCAGACCCC CTGACTGTCCCCCCACCCGGCACAGGCAATGCTCCCACCCCACACGGCAGCCAGACCCCC TGACTCTCCAGGCCATCACGAGAACATTTCCCGAAACTCTCAGCCCGTCCTCTGCAGTAC CCACAGGTGCAGCAGTGCCTACGTACTGGACCAGGACCTCCCCCAGCTGGGCCTGGCCCT TCCTTAGAGCTGCCCCCTCCACTAGCAGGGCCCATGGGCCGCCATGAGATGTCCCTGCTC CCACTCACCTGGGACCAGAGCACCCGGGTGTATACAGGGTGGGACCCCTTGGGGAAGCAG TCGGGCCGCCAGCTGCAGGGGCCAGAGTCCAATGGCTGGGCTGTTTTTTGAGGCAGCTTG GCCTATACAACACCCAGGAGAAAAGGACTTGAGGTTTCAGGATCCCTCACTAAATGACTG TGGCAAACCCAAAGAGATCTTCCAGCCAGACAAGGGCCGAGGGCTTTGTCATTTGGGAAA ACATCCTGGGATTCTCACCCAGCAGAGGCAGCTGGACAGAGTTGTGTCGGATGTGTCCCG GAGGGAGCACGGTGGGGGGACTGGACCCCAGTTTGTGCGCTCCAGGTGGGGTGGGGGTGC CACTTCACAGGTTCTGGGCCCAGCCAGTTCTGCTGCTGAGCAGCCTTGGGTGGGTGCCTT GCCCTCTCTGGGCCTCGGCTTCCCCACCCCACCGTGAGGCATTCCCCAGCACCCACCCCT GGCTCCCAGGTAACTGGCTGCTGATTGGGCCTAGGGGTTAGGGCGTGGGGCCAGCTAGGG AAGACCTGGGGCGTGCGGCACAACGAGGCCCTCTTCCATCCCCACAGGAGCCTGGATCCT GACCAGTGCCCTCCGCGTGGGCCTGGCCAGGCATGTCGGGCAGGCCGTGCGCGACCACTC GCTGGCCAGCACGTCCACCAAGGTCCGTGTGGTTGCTGTCGGCATGGCCTCGCTGGGCCG CGTCCTGCACCGCCGCATTCTGGAGGAGGCCCAGGTGCACGTCCAGCTCCCAGCACCACG ACCGCTGGGGGCCTGGAGGCAGGGGCTCAGAAGGGTTTGGGCAGCGGGCAGAGCTCTGGG AGGACAGGACTCGAGCTGGAGGAAGAGCAGGGAGCGGGCAGAGCCAGCACACGGCCGGCA GGTGGCAGTACCGCATAGGGAACGGCCAGCGTAGACTGTGGCGCGGGCCCTCACCCCCTC CTGTACCACACGGGCCCAGGCCCCGAGCCCTTTCCAAGCCTGGGCAAGCAGCTTCCGTCC CCCATGCTGGGGTCTGTCTAAGGCACTACCGAGGGAGGCCCGGGCAGCCCCTGGTGGATG TTTGGACGCCAGCCCTAGAGTCGGGAAGGAGGTGCTCCCGGCAGCCTGGGCTGTCTCCAT GGTTCTGTCTAAAAGAACCCGCTCCCCACCGCCCCTGCCCCTGACTGTCGAAGGAGGGTC CCCGGGCCCCAGCTGTTCGTCCCTCCTTTTGTCTGAAGGGTGGGGAAACCAAGGCTCGGG CAGAAGCCTTGTGCGGGGCCCCATGGCGTGGTGTGCACGGCCTGGCAGGGAGGATCCCGC AGCGGGACCAGCCCAAGCTGCCTCTCGAGGGCTCAGCCTCGTCTCCCTGCATGGGCGCAG GAGGATTTTCCTGTCCACTACCCTGAGGATGACGGCGGCAGCCAGGGCCCCCTCTGTTCA CTGGACAGCAACCTCTCCCACTTCATCCTGGTGGAGCCAGGCCCCCCGGGGAAGGGCGAT GGGCTGACGGAGCTGCGGCTGAGGCTGGAGAAGCACATCTCGGAGCAGAGGGCGGGCTAC GGGGGTGAGACCCGCCCCAGCCACCCAGGGAAGCCTTGGGACCCAGTGGGGATCCAGGGA CCCGCCTGTGGGAGAGTGGGGGTGACCGCCAGGGAGAAGGGGGAGGGCTTCCCAGGCAGA ACGCACCCCGCATGCCTGAGCACCGAGACCTGGGCCGTGGGGGCCTGGGCCGTGGGGGCC TGGGAGGAGGAGCTGTCTGGGCAGAGTGGTGAAGGAGGCACAGCTGGACAGAGTGGCTCT GACTGGACAGTGACATTCCCACCAGAGCAGGTGCAGTTCTGTTTTCACTGGGCCTTGCCG TGGTCAGAGGCTCCGGGACTCTAAGAGGCAAAATGAGATCGTGAGTTGAAAGAGGGCTAC TTCCCGCCGCCAGGCGTGAGGTATGCTGCCGCCAGAGGGCAGCGTCACCCGAGAAATGGG CACCTCTGGCCAGTCGCACGTTCAAAAGCTGGACTTACTAAGAAAACGCTAGTGTGTAAA TAATATTCATAAACAAAGCATATAATTATTTATAACATCTATGAACAATATACAATATTT AGAAACAGAATTGTAATTTCTTGGCAAGGCCAACTGAGCCCTCTGTTTTTTTTTTTTTTT TTTGAGGCAGAATCTCACTCTGTCCCCCATCCCCCAGGCTGGAGTGCAGGAGTGCAATCT CGGCTCACTGCAGCCTCCACCTCCCAGGTTCCAACAATTCTCCTGCCTCAGCCTCCCGGG TAGCTGGGATTATAGGCATGTGCCACCATGCCCGGCTCTTTTTTTTTTTTTTTTTTTCCC AGTAGAGACGGGGTTGCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGATCTCAGGTGA TCTGCCTGCTTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCGGTC AACTGAGCACTCTTTAGAATTGAAAACACAAAGTCTCGTCAAACTCTAGGGACACAGGCG GAGGGTCTGGCTCTGCTCTGCGGAAGCCCTGCTGGCCCGGGCACCGTTTGGCCAGGCCTG ATTTATCCTCCAGATTCAATCAGGAGGCACCTTTCAAAGTCAGGGGCCCGCCTGCGAGCC CAGTTCCCTGTGGGTGATTCTAAGGCACCTCCAGGCAGTTCACTCCCTCACAGAAGACAG GGGCAGGTCCAGGCCTCTCTGGGGGCTTCACATATAGACATCTCATTTCCAGCTTCTGTT TGGGGGAGAAACCTGAAGACTCCCTCCTGTACCTCTTCAGTTTGCTGAGTGGTCAGGCGC AGCCCACCCAGCAGAGCTCCCTCGATGGTCGAGATGCTGCCTCTGCCATGCTCAGCATGA GCGCGTGCAGTGTGGCAGTGCACCTGTAGGGCTGGGTGCTCCGTTTCTTCCACGTCACTT TGTGTTTTAACAGCCATATGCCAGCTGTTGCCACAAAGTGCGCGTGCTGGGTAGTGTAGG TTAGCATTGGAGCCCTCGGCCCTCATATGGCAGGGGCTGTAATAAGCAGCCTGTGTCACG TGGCCCAGACGAAGCCCACACTTTATTCGGAAGAGCCAGCTTTTGGCCAGAAAATGTGGT GGCCTGAGAGCCTGAGATCCGGGTGGTCACCCCAGGCGGAGGGTCCTCAGGCCTCACGGG TGCCCTGTCCACAGGCACTGGCAGCATCGAGATCCCTGTCCTCTGCTTGCTGGTCAATGG TGATCCCAACACCTTGGAGGTAGGGGCCTGGCTGAGGCCCCCTGGCTGGCCGAAGCCTTG TGGAGGGGTGCGGTGGGTTCTGGGCACCCCTGGGACAGGGCTGAAGGGATGGGGGCACCC CTGACACCTGCATCCAGATGTCGTCGGGCTAATCTGGGGTCCGCTCTCCCCTCCCTCCCC GTCTCAGAGGATCTCCAGGGCCGTGGAGCAGGCTGCCCCGTGGCTGATCCTGGTAGGCTC GGGGGGCATCGCCGATGTGCTTGCTGCCCTAGTGAACCAGCCCCACCTCCTGGTGCCCAA GGTGGCCGAGAAGCAGTTTAAGGAGAAGTTCCCCAGCAAGCATTTCTCTTGGGAGGACAT CGTGCGCTGGACCAAGCTGGTATGTGCTGCCCCCTCCCCTGTCCTCCCGACCCCTCCTCC GGGGGTGGGGCTGGTCCTCTGGGAGAGTTCCTGCAATGCAGCCTCCAGCCCACTCCTCCC ACCTCAGGCTGCTGGGCCCCCCACCCACTCTCGCTTCAGGCCCACAGGGAGCAGAGAGAC CCAGGCAGCCCCTTGGTCTGCGGGTGGTCCCAGGCCGGGCCCGGTGGGCGGTGGGCATGC AGGCTGCAAGGCTCACCTGGGGACGCTGCCTGTGCCTACGCTGGTGTCTACCACGGCCTG CCTCTGCCCCCGTCCTGGCTGAGGCGGCCCCATGGGGGCTCTGTTCTGGTGCCCAGCTGC AGAACATCACCTCACACCAGCACCTGCTCACCGTGTATGACTTCGAGCAGGAGGGCTCCG AGGAGCTGGACACGGTCATCCTGAAGGCGCTGGTGAAAGGTGAGGGCGGGCAGGGTGGGC AAGGCAGGCGCCATTGGGGGGCTTCATGCTCAGAGCCGCTTTGGGGTTTGGCAGCCTGGC CAATGTTTGTGACGCTCGGCCGCCTGCCCCTTCCCAGGAAAGATGACACATGATTCATGA AGCTGTCTGTATTTGGCAAGTTTTATGACGTGTTTTTTACCACAACTTAAAACTATACTT AAAGCTCTCAATTCAGTGGTATTTTTTTGGTGGGGGGGTTGTTTTTTGTTTGTTTTGGTT TTCGGTTTTTTGAGACGGAGTCTCGCACTGTCGCCCAGGCTGGAGTGCAGTGCTGCGATC TCGGCTCACTGCAAGCTCCACCTCCCGAGTTGAAGTGATTCTCCTGCCTCAGCCTTCCAA GTAGCTGGGATTACAGGTGCACCCCACCATGCCCGGCTAATTTTGTTTTTGTATTTTTAG TAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCG CCTGCCTCGGCCTCCCAAAGTGCTGAGGTTACAGGCGTGAGCCACCGCACTAGCCAATTC AGTGGTTTTTAGTATATTCGTGAGGTGGGGCGACCATCACTTTTATCTAATTCCAGAAGC CTTCATCGCCCCAGAAAGAGCCCATACCCCTTGGCACTCACTCCCCATTTCCCCCAGCCC CTGGGAACCATCGATCTGCTTCCTGTCTCTATAGATTTGCTGACGGGCATTTCGTGTCCA TGGTTCCCTGCAGGCAGCGGGAGGGTTTGACGGTTCCTCCGTGTTGAAGCGTATGCCATT CCATGCTTCATTCCTTTTGTAAGGCGGAGTCAGGTTCCAGCCTGTGGACAGACCGTGGTT GATGCGTCTGTTCACCCGCTGATGGAAAATTTTGATGAGCATTTGATGTGCTTTTTGCTG GAGACGAACGCGTGCTGAAGGGCTGGACGCTGGCAGGCAGACACAGCCCCAGCAGGGAGA GGCACTGCTAAGCAGGGGCTGGGGACACCTTGAGGGGACGCTCTGGGAAGGGTGTCTGGA CTGCGGGTGGCTCTGGGTTTAGAAACCTCACCAGGACAAGGAGGTCAAAGAAACCTCCCC GTTTAGGAACTCCCCCGCCTCTTCTCACCAGTCTCAGTTTGGTCCCAGTGGCCTGAGAGA GGCACCGTAGTCTTACGGGGTCCATGGTTGTGGAGGCTGAGGCTGGTGAGCCTCACGTGC GAGTCTGGTGAGGACAGCGGTTTCCAGCAGGCGCACCCAGCCCAGGTGCTGCAGGCCCCC CTTGAGTGACCCTGGTGACCTCACCAAGTCATGGCCAAATGCCCTTGCCCGTGGAGGAAA CGTGGCCCAGCTTGCTCCCCCGACAACATCCAGGAAGGGTGTCCTGGACCTTCAGTGCCA GGAAGTGGCCTCGAGGCCCAGGTGTTAGCTGGGGTACCCCCGTTGCAGCCGAGGAAGTTG CCTCACATGGGAGCAGACGGGCCGTCCCGACGCAGACCAGGGCAGCACGCTTTCTCCTGC GGTTTGTACAAAGTCTCGTGCCTCCTGCTGGTGCTCAGAGGTGGCGCATGTGCCCCCTCA AGTCCCAGCGTGAAGTTCCCGTTTCCGCGTCTCTAGGCAGCGCACCTTTGGGGACCCTGT GCCCCGGCTCTGTGAGGCCCTCAGCTCCACCCTCACCAGTGCCTGCCTGCTCTGCCCACA GCCTGCAAGAGCCACAGCCAGGAGCCTCAGGACTATCTGGATGAGCTCAAGCTGGCCGTG GCCTGGGACCGCGTGGACATCGCCAAGAGTGAGATCTTCAATGGGGACGTGGAGTGGAAG GTGCCTCCCAGCCCTGCCTACCCACCTCCCCATCATGGCACTGCCCGAGCTGCCCACGCT GCCTGCTCCTGCACCCTGTGGGCTGCTTGGCTGAGCCCGTTCTGCCCAGCTGTCCCAAGG TCCGGGGCAAGACCAGGCCACGGTTCTGCCCGGGCTTCTGCCTCGCTCACTGGCCCAGGC AGAGCTGGCTGGGTGCCGGCTGTCCCCAAAGCCCAAGGGGGTTGTGACACCCTCAGCATT TGCTCACGACTGGCCCCTCTGTGCCCGCCCCAATGCAGGGGGCAGGCTGGGGTGCAGGAG AGCGAGAGGGTCTGCGTGACCTGGCCCTGGGGATGGATCCCCATGCTCCCTGCTCTCTCC TTCCTTGGACCCCCTCCTCCTGTCTCTCGCTCACTCTCTTGTCCCCCTTCCCTCGGGTGC CCATGGCCGCCAAGTCCTGTGACCTGGAGGAGGTGATGGTGGACGCCCTGGTCAGCAACA AGCCCGAGTTTGTGCGCCTCTTTGTGGACAACGGCGCAGACGTGGCCGACTTCCTGACGT ATGGGCGGCTGCAGGAGCTCTACCGCTCCGTGTCACGCAAGAGCCTGCTCTTCGACCTGC TGCAGCGGAAGCAGGAGGAGGCCCGGCTGACGCTGGCCGGCCTGGGCACCCAGCAGGCCC GGGAGCCACCCGCGGGGCCACCGGCCTTCTCCCTGCACGAGGTCTCCCGCGTACTCAAGG ACTTCCTGCAGGACGCCTGCCGAGGCTTCTACCAGGACGGCCGGCCAGGGGACCGCAGGA GGGCGGTGAGCGGGGGCTCCGTGGGGATGGAGGGCGAGGCTGGGGCCGCAGCAGGAGGCC GACGCCCGTGTCCTCCAGGAGAAGGGCCCGGCCAAGCGGCCCACGGGCCAGAAGTGGCTG CTGGACCTGAACCAGAAGAGCGAGAACCCCTGGCGGGACCTGTTCCTGTGGGCCGTGCTG CAGAACCGCCACGAGATGGCCACCTACTTCTGGGCCATGGTGAGCCCAGGCCGCGGGCCC AGCGCGGGGGCAGGGGAGGGGCGGCCTCCTGAGACCAGGTCTCGTAGGGCCAGGAAGGTG TGGCAGCCGCACTGGCCGCCTGCAAAATCCTCAAAGAGATGTCGCACCTGGAGACGGAGG CCGAGGCGGCCCGAGCCACGCGCGAGGCGAAATACGAGCGGCTGGCCCTTGGTGAGTGAC CGGCGGCTGGGGCCGGGCCCGCGCGCGGGGGAGGATGTGACGGAGGGGTCGGACGAAGGG TCCTGGGCCTCGCCAGGGCTGCCTGTTACCGCCGTGGGGCTCCAGGTGCCCTCAGGGGCC TCCTCCATAGGAGAGGACAGACGGCTCTGCCTGGGGTGGAGGCGGCCCCAGACCCTGAGT GTGGGACCGCTGTGCACGTGGTGAGGACGATACAGCCTCACACCCCGGGCATACACTGGG CCCTGCCGCAGGACGAGGGACATTTAGCGTGGCAGAGGTTCCCTTTGTCCTGCTGGGGGA GGGACAGAGCCGGAGAAGGACGGAGGTTCAGGAAGGGCCCGGAGCAGGCCGGAGGGGGCA GAAGGCCTGGCTGGGCCCTGCGTGTTGAACGCAGGGTGCGGCTGCAGAGCCCAGGTCTGG GCAGGGGATGGAGGAGGGGCGTCGGGGGCCGGGCCGGGCATCGGCGTCTCGTCCTAGCGG CCAGGGCCTCCGGGGGCAGACCTCTTCTCCGAGTGCTACAGCAACAGTGAGGCCCGCGCC TTCGCCCTGCTGGTGCGCCGGAACCGCTGCTGGAGCAAGACCACCTGCCTGCACCTGGCC ACCGAGGCTGACGCCAAGGCCTTCTTTGCCCACGACGGCGTTCAGGTGAGTGCCAGCTGT CCTCGAGGAGAGCTGCCAGGGGGTGGGGTGGGCGGGCGAGCTGGGCCCAGCTTGAGTTGA CTTCCCAGCCTGCAGCTGCCCTGTCACTCCCGTCCTCAGCACAGAGGGGGCGGGGTGGGG CTTCTGTTCCTGGAAGGCGCCCACCTGGCTTCCTCCACCAGGCACACTCCTCCTGCCTCT GGCCTCAGTGGAAGTGGCACTTCCTCCTCTCAGTCCTCCCCAACCCCCAAGCCCAATCTT TTCCCTAGTGAAGGGTACAGCAGCTCAACCCACACCCCTGGGATGAGTGGCCCAAGGAGC ACATGCCCACCAGGACGGGGGCTCCGGGAGGGAGGGCTGGGCTGGGCACCCCTTCAGCTC ACGTGGGCCAGGCACCTGGGGGAAGGGCATTCCTGGGGCAGGGCGCAGCCTGGGCAAAGG TGCAGAGTTGGAGCCGACAGTTTTGCCTTCACCTCAGGCCTTCCTGACCAGGATCTGGTG GGGGGACATGGCCGCAGGCACGCCCATCCTGCGGCTGCTAGGAGCCTTCCTCTGCCCCGC CCTCGTCTATACCAACCTCATCACCTTCAGGTGGGTGAGGCCTGTGAGCTGCCCGGCCAG GACAGGCAGCAGTGCGAGTGCCGGAGCTACGGGGAGGGCCTGGGCCTCGCAGGTGCTGGT GGTAGCCTGACTCTGTAGCCCCCAAGTCCAGCCTCCCTGCGGGTCCCACTCCCCACAGCC CCTGCATCCCAGTGGGCACTTTGATGGCCAAGCGCCTGGAGCCAGGCAGGCGCCTCTGGG AGCCCTTCCTGCGGGCCCTGAGCTCTCCTGTGCTCGCAGTGAGGAAGCTCCCCTGAGGAC AGGCCTGGAGGACCTGCAGGACCTGGACAGCCTGGACACGGAGAAGAGCCCGCTGTATGG CCTGCAGAGCCGGTGCGAGGCACAGGGCCAGGCAGGGTGGAGGGGACTGGCGGGTGGTGG CTGGGAGGCTGGACTCTGGTGGGGCACCCGGCTGGGCGCCAGCCTCACCACTGCGAACTT CTCTGCGGCACAGGGTGGAGGAGCTGGTGGAGGCGCCGAGGGCTCAGGGTGACCGAGGCC CACGTGCTGTCTTCCTGCTCACACGCTGGCGGAAATTCTGGGGCGCTCCCGTGACTGTGT TCCTGGGGAACGTGGTCATGTACTTCGCCTTCCTCTTCCTGTTCACCTACGTCCTGCTGG TGGACTTCAGGCCGCCCCCCCAGGGCCCCTCAGGGCCCGAGGTCACCCTCTACTTCTGGG TCTTTACGCTGGTGCTGGAGGAAATCCGGCAGGTCGGTGGCCACACTAGCCTAGGTCCCC TCCACTCTGCAGCTTCAGGTTGGGCAACCTAAGCTGGGTCCTGCCCTCGCAGGGTGGGGC TCCCCAACTGTAAAACAAGAACAGCATGGGGGCCTCCCATCTTCCCAGTCACCAGCGGCC ATGATCCTGGTCAAAGACCGAGCCCTGAGCCCTGCTCCAGACTGAGCATGACCATGGTCT CCCTCGTCAGAGTCTGAACCCTGACCTGTATCACGGACTGAGTCCAGACACTGCATAAAC TGATCCCTAGACCCTGGGCACAAAGAGGCCCTGGCCCCAAGTGGAGACTGACCTCACCTT CTGTCCCCAGACAGCCCTGGAATAGCTTCAGTGGACCCCTAGTCCCACTGGTAGCCTCGG CCCTGGTCATAGATGGAACCCTGATCCTTACAGATCCAAGCTTGTCCAGGTAGGGCTGTC CCCAGCGAGGGCGGCTGGACAGCTGTCAGTGGACTGCCCACCTCCCTCCCAGGGCTTCTT CACAGACGAGGACACACACCTGGTGAAGAAGTTCACACTGTATGTGGGGGACAACTGGAA CAAGTGTGACATGGTGGCCATCTTCCTGTTCATCGTGGGTGTCACCTGCAGGTCTGTGGG GCCCAGAGGCCGTGTGGCCTCAGGGCGGCTTGTGGGCAGGCTTCCAGATGAAGCCACTCA GGTTGGGTGTGGCGGTGGCACTTGTGGTCCCAGCTACTCAGGAGGCTGAGGTGGGTGGGT CACTTGAGCCAGGGAAGTTGAGGCAGCAGCAAGCCGTGATCATGCCACTGCACTCCAGCC TGAGTGACAGAGCAAGACCCTGTCTCTTAAAAATAAATAAACAAAAGATGAAGCCACTCA GGGCCCAAGGAGTCCTGGCCTGGCCCTGGCCCTGCCCGCAGCCAGCATGCTGTGTGCCCC TGGGGAAGCCTCTGCCCCTCTCTGGGCCCCGCAGCCGCATCAGCCTCCCATCCTCCAGGA TGCTGCCGTCGGCGTTTGAGGCTGGCCGCACAGTCCTCGCCATGGACTTCATGGTGTTCA CGCTGCGGCTGATCCATATCTTTGCCATACACAAGCAGCTGGGCCCCAAGATCATCGTGG TAGAGCGCATGGTGAGCCCCCGGGGGCCCTGGCCCTGGCCCTGGAGGGACAGCAATCCCC TGCCTGGGCCCCACCCGGCTGGCCGCTGACGTCCCTCTCTCTGCCCCTGCCCCGTGGAGA TGAAGGACGTCTTCTTCTTCCTCTTCTTTCTGAGCGTGTGGCTCGTGGCCTACGGTGTCA CCACCCAGGCGCTGCTGCACCCCCATGACGGCCGCCTGGAGTGGATCTTCCGCCGGGTGC TCTACCGGCCCTACCTGCAGATCTTCGGCCAGATCCCACTGGACGAGATTGATGGTTTGC ACACAGCCAGCGGGGGCAGGGGCAGGGAGAAATTGGAGCCCTGTGTGCACAAGCCCTGGG CATGAGGCTCTCCAGAGAGGTCTGTTGGGGCCATGGAGACCCCAGCCTGGAGCAGAGATG GGAGAAGTGGCTGAGGCCTGGTCCCCAGGCCCCCCACACCCCAAAGGGCCAGGCCTGGTT CCTGAGGTAGAGGCAGCTCCAGTCACGGAGCCCCGACCTGGGACCTGGGGCCTTGGGCTG GGAAGGAGACACAAGGAGACCCCAAGGCAGCCAGGGCTGCCTCCTGCTTGGGGAGGCCAA GCAGCAAGTCTTGCTCTGGGGGTGGTCTATCGGTGGGGAAGGGATAGGCAGGCACTAAGG GCACAGAGTGGGCCCAAAGGCTGTCCCAGCCATCATCCGGGGTCTGGGCCCTCCAGCTCT CCTCACAGCCCCTGGCCTCTGCCCTCCCACAGGGCCCTGCTTGGCCTAGGGCACCCACCA GAGCCCCTACGCCGTCCTGCTGGCAAGGCCCCTTCGCCATTTGGCCGCTCCTAAAGGCAC CCTGGCTGCTCCTGGGGACCCACCCCAATGTGTGTGTGTGGCCTGCCCATGCCTATGGGT GTCCCCAGGCCGACCCCTGTAGCTGGCTGGGGCTGGTGGAGGCTCTGGAAACTTTTTCAT AAGCCAGTGCAGTGGGGAGGGGGCGGGGGTCAGAGCCGCTTGGCCATGGGGGCCTCTGTA GTGATGGGTTGGTGGGGAGCTCTGGGGTGGGGCAGGGACCTGTGCAGGCCCCTGGGATGG CTGGGACTCAGTGAGGAGCCCCAACCTGGAAAGGGACGCACCCCTCTGGGAAGGTGGACC AGCAGCCAGCCCGCCCCTGGGGCCCTCGAGGGGTGCCGCAGACTTGGAGACCCGGCAGAG AAGGTGCAGGGAAACTGCTCAGGCGGTGTCAGGCGGCTGGGGCTGCCCGGCACGGGGCAG TCATGGCACAACGTGCTGCCCAGGCCTGACCCCGACCTCTGTGGAGTGGCGCTCAGGACC CTCGATAAATATTTGTTGAGGGGATGACGGCCAGACCGGAGCAAACACAGGCCTCCGGGG ACAGGCGGGGGCGACGCCGTGATGGAAACCGCCTCTCCCAGCGCGGCTCATTTCCTTGGG CTGTTTTCTCAGCCCCCGCAGCCCCTCCTGACATTTTGGTGTTTGCTCATCACAGGCATT CATTTTCCAGGCCATTAGTTTAACCAGACCCTGCCTGCCTGCGACCCCACCTCGCCCTCA CCATACGGCCTCCAGCACTGCCCGTCCGCAGGGCCCCTCGGGGCAGGAGGAGCTCTAGAC GGGCGCCTCCAGCCAGGGCAGGGTTGGGGGTCCCCTCTTTCTTGAGTGGCTGCATCTCTG GTGGGCCAGTCTCAGCGACTCGTATGAGGAGACAGGCCTGGCCATAGCCTCCTTCTCGAC GGGAGAAGGCAGGGAAACAGACTCCCGAGGGGCCCCTGCTCCGAGTGCTGCCTCAGGGAG GTCTGCGGTGCTGCGGGGATCTCAGAGCCCCGTGCTGAAACGCCTGCAACAGGGCCAGCC CCGGCCGCCCACTGAGAGTCTCAGACTTGTCACTTCCCCTCCCTGAGCTGCAATTCCTTG GGCTCCGTTCAGCTGCCGAGCAAGTATCTGGGCCCTTCAGGTTGAACCCCAGCCACTCAC TGTGACCCAGCCCCTCATGCTGCTAGGCAGGGAGTTATTCACTAACACATGCTGGGCTGA GAGGGAGACTGAGGCTCAGACAGTTCCTGTACAGCCTGCAGGTCTCCTCAGAGCCCAGAA CAGACCCCTGCCCCACTCTGCACTCGTGCCGAGCCGGAGCTGGGGTTGAGCTGTGGTGAC GAGCTTGTTCTCTGGGTCTCCAGGCCCCAGGGACAATTTAATTTCCAGCCCGGCCTGGTG GCGCCTTCCCAAATCACAGAGTCGGGGAGGGTGTGGGGGTCTCATTCCTCAGAGCTGCCT TTATCAGACAGATTTACGGCTTCACAAACAGGCTCTCCAGGCTGGCCCCGGCCCGCTCCT CCAGAGTGCAGGGAGGAGAGGGGGTCATCAGTCTGCCCAGGAACAGATTCATGGGCTGGA GGTGGCCAGGGCGGACAGAGGAGGGGCAGGCCTAGGGTGGGAGCGTGGGGAGGGCTGGCG CTCACTGACTGCCAGTGCACACACAGACACTCAATAACTCACACACGGGCCAACGCGTCA CACTAACTCACTCGGGAGAAACAAGGCAGGAATTCACCCTAGGAGGGAGAACGGACCCCT CCAGCTCAGGACCCAGGCACAGAGGCAGGAACCTGGGAACAAGGAGACCCCCCAGAACCC ACCGCAGGGCAACCTGGAGCTGGCAGGCACTAAGATACACTTGAATGTGCCCGTGTGTGC CAGTGTGCTCACACGCAGACTCACACATGAGCATGTGTGCCAGGCACATCCAATCACATG TACAGGCTCACACAGACACACGCCAGCGTGCAGGCTGGGGAGGGAGGAGAGAGCGGAGCT CCCATTCGGATATGGAGGGGATATGTGGTCCTGGACGGCCAGGGCACACTCTGGCCTCTG GCTGGGACCCTGAGCACCCTGACGCCCACTGCGGCTCCTTCCTCCCTCCTCCCTCCTCCT GCCCCGCAGGCTGGGGTGGGGTGAGGGTCCAGGGTTGAGCCCTACAAGGGAGAAGCAGGT GTGAGGGTCTGGTTTTAAGGGACTGGAGTGAGATCTGCCACCCCTCCAGGGTGTCCCTGC CCAGGGCCGAGGGAGCTCAGCCTGCAAGCTCCCAGAGTGTGCCGCCTGAAGAATGTTCTT GACTTGAGTGGCCCAGTGCGGGATCGGTGCCCTCAGAGCTTGCAGCAAGCCCAGTCTGGA GCCTGCTGGCTCAATACATTTTGGAAAGGTGGCGGAATTACTTGCCAGCTTGGGGTTTAA TCACAGGCATTAGTGCTGTAGAGGCTCTGAGAAGTCCTGGGCCCCATCTCCCTTTCCTCG GCAGCTCTCCCCAAACCTTCAACAGCAGAGGCTTTTTTCGGAGGAGGGGTGGAGGTTTTA ACACATCCAACAACCAGGAGAAACCTGGGTCCCGTGACCCCTCTGTCCCCCACCTTCCAT CCCTCCAGGGGTCTTGGCTCTACTTCCAGGGCCTGTGATCTTGGCTGACTCCAGCCCCTG GTGGAAGCTCAGCAGACATGGCAGAGGGGGCCCAGGGTGGGGCTCACCACCCGTCTGGTT CTGGTTTGCTGTGATGGGGCTTTCACTGCTAAAACCCAGGCCGCCCTGGGTGAACTGGGA CAGTGGGTCACCCAACCAGCACCCCGTCCCCTGGGTTCAACACCAGGACTCAGCGCTCTA TCTCGGGGCATTTGCCTAAGGCCGCCCTTGTGGCTGCCCCCGGTCTGGTCCCCACAGCAC CCTTGCTTTCCAGAAGCCCGTGTGAACTGCTCCACCCACCCACTGCTGCTGGAGGACTCA CCATCCTGCCCCAGCCTCTATGCCAACTGGCTGGTCATCCTCCTGCTGGTCACCTTCCTG TTGGTCACCAATGTGCTGCTCATGAACCTGCTCATCGCCATGTTCAGGTGACTCCACCCA ACCCCTGGAGGAGAGAGCCCTGGAGCGGAGGGAGCAGAGGGTCATTCCCCAACACCGCCT CCTTTGCAACCCACCTGGTGTGCTGCAGAGGGTGAGGCTTGGTGCCTCAGGGCAGATAGA AGGTGGCATAGCCTGGACTGCAGGGCTTTGCCTGCCCAAGACCGGGAACTCTGTGGGCCA CCCTCCCAGTCCCAGGAAGCAGGGCCTGGGTCTTTGGGGGACCGGTGCTGTGGCAAGAAC TCTGGGCTTGTCCAGGAGAGCAGAGTGGACAGGGGAAGACCCAAGGAGAGTGGACCCCTC GTGACACACCCCAGAGGCAACGCAGAAGCAGTGCTGGGCCTCAGTTTCAAAAAGGGCTCC CCAACAGCAATCAGGGTGCAGGGGGATGCGTCCCCCAAGTGGTCGTGGGGAGCCGGTAGG TGACGGCTCAGCTGTGCCCCTGCAGCTACACGTTCCAGGTGGTGCAGGGCAACGCAGACA TGTTCTGGAAGTTCCAGCGCTACAACCTGATTGTGGAGTACCACGAGCGCCCCGCCCTGG CCCCGCCCTTCATCCTGCTCAGCCACCTGAGCCTGACGCTCCGCCGGGTCTTCAAGAAGG AGGCTGAGCACAAGCGGGAGCACCTGGGTGAGGCCGAGCACAAGCGGGAGCACCTGGGTG AGGCCGAGGTGGCGGGTCCCAGGGCGGGGCTGTGCGCTGGAGGCAGGTCTGGAGAGACCT GGACCCCTCCTCAGCCCTGTGGGTCCTCAGCTGGGCTCTGTGCAGGCTGGCACAGCTGAG CCCGTCCACCCGCAGCTTGGCCGTCCTTGCACAGGGCCATGCTTGCCCTCCATCCCTGGC TGGGCCCCACTCACTCCTTCTGCCTGGCCCACCTCGCCCCGGGACCAGGCCTGGGCTCTG CCACTGACGCCCACATGCTCTAGTAATGCTGGCTGCCACCTGGCTTTCCCAGAGAGAGAC CTGCCAGACCCCCTGGACCAGAAGGTCGTCACCTGGGAGACAGTCCAGAAGGAGAACTTC CTGAGCAAGATGGAGAAGCGGAGGAGGGACAGCGAGGGGGAGGTGCTGCGGAAAACCGCC CACAGGTGCGGGGGCCTGTCCTGATCACTGGTGGGTATCGGGCTGTCTTTAAGCGGGGAT GTGCCATTGGCGCCAGTGACAGAGGATCTGAGCTGGCGAACTGAAGCTGAAGGGGTAGGG GCAGGGCTCTGGCCGAGCCCAGGGGCCTAGCTTTCCAGCCTGACCTGTGCAGGACCCTGC TGGGACGCCTGGCCAGGCAAAAAGGGAGCGTGCACAGTGACCGTGGCGCCCTCCCTGCTG TGGTCTCAGGGTTGGGACTACCCACCCCTGGCTTCCCTCCAGCCCTGGCTCCAGGGGCCT GTCCCCGACTGCCTGCCCTGCACCGTCTTTCTGGGTGGTGCGCCCAGGCAGGGATGGCAC CCTAGCCCTACTGGGAAGGCATAGAGCGCTCTGTACTGCACCAGGTGCACTTTGAGGGGT CCTGGTGCCACCAGATCTGGGCATGAGGGAGGAAGGGAAAGGGCCAGGGCACCCCAAACT CGGGCACACAGGGAGGCCTGGGGGGATGGGGAGGCTCCCCACACGCAGAGCACCGCGTGG CCATCCACAGCCTGACCACCTGCTCCTGCCGCAGAGTGGACTTCATTGCCAAGTACCTCG GGGGTCTGAGAGAGCAAGAAAAGCGCATCAAGTGTCTGGAGTCACAGGCAAGCGAGCCCC AGAGCTCCTCTCCCTGATGGGAGGCGGGTGGCTGCGTGGGGCTACTGGGATGGGTCCACA GCCCTGCCCGGTCACTCACAGAGATGAGGCAGGCCAGAGCCAGGACAGGAGCACCCCAGT GGGCAGAGGAGCGTTCTGGGGAAGACAGGCCGTCCCCACCTGTGCCTCCTCCCACCCTGC CACTTGGGAGGCTACAGCCTTAAATGAGGGGTCTCACATTGAAGACCCCTCGCCTTTCAC TCTACACGCCTCACGGGAGCCTCACTCACCCCTGCCTGTGAGCGGCAGCTCTCAGAGGGA GGAGTCACAGGGCAGCGGGGGCCCTGGCAGGAGAGGGGAGATGGGGAGGCTGCCTGTCCC CTGCTGTCCTGAGAGAGCCCTGGAGCTTCCCGGACGTGTTTCCCTTCTCCAGATCAACTA CTGCTCGGTGCTCGTGTCCTCCGTGGCTGACGTGCTGGCCCAGGGTGGCGGCCCCCGGAG TAAGCCTGTTTGGGGAGCGTGGGATGAGGGTGGGCATGGGCACCCACTCTGCAGCGGCTG GGGGGCCGTAGGCTGTGCTGTGTGCTCTGCCTTCCCTGCCTGGCCCGGGAGTCTCAGGAG GCCTTGGCTGGACGCGGCTCTTCAGGGTGGTGTGGGTGCCCTCTGACGGAGTCCCTGCCT TGGCCAGGGCCGAATGTGCTTCACTCAGACTCTTGAGGCTCTGCCTGGCGTGGGCCCTAT TGGACTGTCCTGCTCAGCAAGCAAACGGGCCCCTCGGCCTCAAGGGGGCTGCTTTCCTAG TCCCAGGAGTGCAGGCAGAGGCCTGGTTGTCTCTGGGCTCCCCATCTTCCCCAGGCTGGC CTGTGGGGACTCACTCTGAGAGCCACGGCGTCCTGGCCCTTGCCTCTGAGCCAGCTACCT CTCCCCTTCCTGGGCCTGCCTTGCTGGTTCCCACCGCTCAGGGGGGCCTTCCTTCCCAGC AGGCTCTCAGCACTGTGGCGAGGGAAGCCAGCTGGTGGCTGCTGACCACAGAGGTGGTTT AGATGGCTGGGAACAACCCGGGGCTGGCCAGCCTCCCTCGGACACCTGAGCTGCTTGGCC TGCCACGTGTGGGGCCACCTCTCCTCAGCTGGCCACCCTGCACGTTGTGCACTGACCTTT GCCGACCTCCAGCGGAACCCCCCAGGGGGCACCAGCCCCCCAGCAGACAATGGCCCTCCT GGTGCCTCACCACAGACCCTCACCCAAAGGAACCGCTCCTTGTCCCTCCTGGCCTCCCCG GAGGCACAGCAGTGTCATGGGGCTGTCTCCCCTGACAGGCACAACTCCCCGGGCAGAAAA CGTGCCCCACCGCATCCCTACCTGGAAACTGACCAGCCTGCACTGTGGAAAAGCTGGCCC TGTGGCGTGACGGGGGAGCACCCCCATCCAGACTGCGAAGCTGCTCTGGGGTCTGCACCC ACCCCTGCCCTGACTTGTGTTGCCTGACAAGAGACTCATCTTTTTTTGAAA OMIM ID 604600